Predicted complex interactions
CCL22_HUMAN + CCR3
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR3 View partner entry
- Partner description
- UniProt: P51677; Gene: ccr3_human; Family: Chemokine
- Interactions detected
- 91
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | TRP 90 | 2.60x60 | VdWContact |
| GLY 1 | NTc.Cm35 | SER 110 | 3.29x29 | HBDonor |
| GLY 1 | NTc.Cm35 | SER 110 | 3.29x29 | VdWContact |
| GLY 1 | NTc.Cm35 | TYR 172 | 4.64x65 | HBDonor |
| GLY 1 | NTc.Cm35 | TYR 172 | 4.64x65 | VdWContact |
| PRO 2 | NTc.Cm34 | TYR 41 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 41 | 1.39x39 | VdWContact |
| PRO 2 | NTc.Cm34 | TRP 90 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TRP 90 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm34 | TYR 113 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 291 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 291 | 7.43x42 | VdWContact |
| TYR 3 | NTc.Cm33 | SER 262 | 6.58x58 | VdWContact |
| TYR 3 | NTc.Cm33 | MET 283 | 7.35x34 | Hydrophobic |
| TYR 3 | NTc.Cm33 | MET 283 | 7.35x34 | VdWContact |
| TYR 3 | NTc.Cm33 | GLU 287 | 7.39x38 | HBDonor |
| TYR 3 | NTc.Cm33 | GLU 287 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm32 | LEU 284 | 7.36x35 | VdWContact |
| GLY 4 | NTc.Cm32 | GLU 287 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm32 | GLU 287 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm31 | TRP 90 | 2.60x60 | Hydrophobic |
| ALA 5 | NTc.Cm31 | TYR 93 | 2.63x63 | Hydrophobic |
| ALA 5 | NTc.Cm31 | TYR 93 | 2.63x63 | VdWContact |
| ALA 5 | NTc.Cm31 | VAL 94 | 2.64x64 | Hydrophobic |
| ASN 6 | NTc.Cm30 | TYR 172 | 4.64x65 | HBDonor |
| ASN 6 | NTc.Cm30 | TYR 172 | 4.64x65 | VdWContact |
| MET 7 | NTc.Cm29 | MET 33 | 1.31x31 | Hydrophobic |
| MET 7 | NTc.Cm29 | MET 33 | 1.31x31 | VdWContact |
| MET 7 | NTc.Cm29 | ASP 280 | 7.32x31 | Hydrophobic |
| MET 7 | NTc.Cm29 | ASP 280 | 7.32x31 | VdWContact |
| MET 7 | NTc.Cm29 | MET 283 | 7.35x34 | Hydrophobic |
| GLU 8 | NTc.Cm28 | ARG 30 | 1.28x28 | Anionic |
| GLU 8 | NTc.Cm28 | ARG 30 | 1.28x28 | Hydrophobic |
| GLU 8 | NTc.Cm28 | ARG 30 | 1.28x28 | VdWContact |
| GLU 8 | NTc.Cm28 | MET 33 | 1.31x31 | Hydrophobic |
| GLU 8 | NTc.Cm28 | MET 33 | 1.31x31 | VdWContact |
| GLU 8 | NTc.Cm28 | HIS 97 | 2.67x67 | HBAcceptor |
| GLU 8 | NTc.Cm28 | HIS 97 | 2.67x67 | VdWContact |
| ASP 9 | NTc.Cm27 | ARG 30 | 1.28x28 | Anionic |
| ASP 9 | NTc.Cm27 | ARG 30 | 1.28x28 | HBAcceptor |
| ASP 9 | NTc.Cm27 | ARG 30 | 1.28x28 | VdWContact |
| ASP 9 | NTc.Cm27 | TYR 93 | 2.63x63 | HBAcceptor |
| ASP 9 | NTc.Cm27 | TYR 93 | 2.63x63 | VdWContact |
| ASP 9 | NTc.Cm27 | LEU 182 | - | Hydrophobic |
| ASP 9 | NTc.Cm27 | LEU 182 | - | VdWContact |
| VAL 11 | NTc.Cm25 | LEU 23 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | LEU 177 | - | Hydrophobic |
| ARG 14 | NTc.Cm22 | CYS 24 | - | Hydrophobic |
| ARG 14 | NTc.Cm22 | GLN 265 | 6.61x61 | HBDonor |
| ARG 14 | NTc.Cm22 | GLN 265 | 6.61x61 | VdWContact |
| ARG 14 | NTc.Cm22 | ASN 271 | - | HBDonor |
| ARG 14 | NTc.Cm22 | ASN 271 | - | Hydrophobic |
| ARG 14 | NTc.Cm22 | ASN 271 | - | VdWContact |
| ARG 14 | NTc.Cm22 | ASP 272 | 7.24x23 | HBDonor |
| ARG 14 | NTc.Cm22 | ASP 272 | 7.24x23 | VdWContact |
| ARG 14 | NTc.Cm22 | SER 276 | 7.28x27 | VdWContact |
| ASP 15 | NTc.Cm21 | VAL 20 | - | Hydrophobic |
| ASP 15 | NTc.Cm21 | ASN 271 | - | HBAcceptor |
| ASP 15 | NTc.Cm21 | ASN 271 | - | VdWContact |
| TYR 16 | NTc.Cm20 | VAL 20 | - | VdWContact |
| VAL 17 | NTc.Cm19 | VAL 20 | - | VdWContact |
| ARG 18 | NTc.Cm18 | VAL 20 | - | Hydrophobic |
| ARG 18 | NTc.Cm18 | VAL 20 | - | VdWContact |
| TYR 19 | NTc.Cm17 | TYR 17 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | TYR 17 | - | VdWContact |
| TYR 30 | NTc.Cm6 | PHE 178 | - | Hydrophobic |
| TYR 30 | NTc.Cm6 | PHE 178 | - | PiStacking |
| TYR 30 | NTc.Cm6 | PHE 178 | - | VdWContact |
| SER 33 | NTc.Cm3 | GLU 175 | - | HBDonor |
| SER 33 | NTc.Cm3 | GLU 175 | - | VdWContact |
| ASP 34 | NTc.Cm2 | GLU 175 | - | HBDonor |
| ASP 34 | NTc.Cm2 | GLU 175 | - | VdWContact |
| ASP 34 | NTc.Cm2 | LEU 186 | - | Hydrophobic |
| SER 35 | NTc.Cm1 | SER 184 | 45.51x51 | VdWContact |
| SER 35 | NTc.Cm1 | ARG 196 | 5.35x36 | HBAcceptor |
| SER 35 | NTc.Cm1 | ARG 196 | 5.35x36 | VdWContact |
| PRO 37 | CX.5 | VAL 192 | 5.31x32 | VdWContact |
| PRO 37 | CX.5 | TYR 193 | 5.32x33 | Hydrophobic |
| PRO 37 | CX.5 | TYR 193 | 5.32x33 | VdWContact |
| PRO 37 | CX.5 | ARG 196 | 5.35x36 | VdWContact |
| ARG 38 | cxb1.1 | TYR 193 | 5.32x33 | HBDonor |
| ARG 38 | cxb1.1 | TYR 193 | 5.32x33 | Hydrophobic |
| ARG 38 | cxb1.1 | TYR 193 | 5.32x33 | VdWContact |
| VAL 42 | cxb1.7 | LEU 23 | - | Hydrophobic |
| LYS 49 | B1.1 | LEU 22 | - | Hydrophobic |
| GLU 50 | B1.2 | LEU 23 | - | HBAcceptor |
| GLU 50 | B1.2 | LEU 23 | - | Hydrophobic |
| GLU 50 | B1.2 | LEU 23 | - | VdWContact |
| ILE 51 | B1.3 | GLY 21 | - | VdWContact |
| CYS 52 | B1.4 | GLY 21 | - | HBDonor |
| CYS 52 | B1.4 | GLY 21 | - | VdWContact |
