Predicted complex interactions
CCL25_HUMAN + CCR3
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR3 View partner entry
- Partner description
- UniProt: P51677; Gene: ccr3_human; Family: Chemokine
- Interactions detected
- 89
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | TYR 113 | 3.32x32 | Hydrophobic |
| GLN 1 | NTc.Cm29 | HIS 114 | 3.33x33 | HBDonor |
| GLN 1 | NTc.Cm29 | HIS 114 | 3.33x33 | VdWContact |
| GLN 1 | NTc.Cm29 | GLU 287 | 7.39x38 | Cationic |
| GLN 1 | NTc.Cm29 | GLU 287 | 7.39x38 | HBDonor |
| GLN 1 | NTc.Cm29 | GLU 287 | 7.39x38 | VdWContact |
| GLY 2 | NTc.Cm28 | TYR 93 | 2.63x63 | VdWContact |
| VAL 3 | NTc.Cm27 | ARG 30 | 1.28x28 | Hydrophobic |
| VAL 3 | NTc.Cm27 | TYR 93 | 2.63x63 | Hydrophobic |
| VAL 3 | NTc.Cm27 | HIS 97 | 2.67x67 | Hydrophobic |
| VAL 3 | NTc.Cm27 | HIS 97 | 2.67x67 | VdWContact |
| VAL 3 | NTc.Cm27 | LEU 182 | - | Hydrophobic |
| PHE 4 | NTc.Cm26 | LYS 26 | 1.24x24 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ARG 30 | 1.28x28 | HBAcceptor |
| PHE 4 | NTc.Cm26 | ARG 30 | 1.28x28 | VdWContact |
| PHE 4 | NTc.Cm26 | MET 33 | 1.31x31 | Hydrophobic |
| PHE 4 | NTc.Cm26 | MET 33 | 1.31x31 | VdWContact |
| PHE 4 | NTc.Cm26 | ASP 280 | 7.32x31 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ASP 280 | 7.32x31 | VdWContact |
| PHE 4 | NTc.Cm26 | MET 283 | 7.35x34 | Hydrophobic |
| GLU 5 | NTc.Cm25 | LYS 26 | 1.24x24 | VdWContact |
| GLU 5 | NTc.Cm25 | ARG 30 | 1.28x28 | VdWContact |
| GLU 5 | NTc.Cm25 | LEU 182 | - | Hydrophobic |
| GLU 5 | NTc.Cm25 | LEU 182 | - | VdWContact |
| ASP 6 | NTc.Cm24 | LEU 23 | - | Hydrophobic |
| ASP 6 | NTc.Cm24 | LEU 23 | - | VdWContact |
| ASP 6 | NTc.Cm24 | CYS 24 | - | VdWContact |
| ASP 6 | NTc.Cm24 | GLU 25 | - | VdWContact |
| ASP 6 | NTc.Cm24 | LYS 26 | 1.24x24 | HBAcceptor |
| ASP 6 | NTc.Cm24 | LYS 26 | 1.24x24 | VdWContact |
| CYS 7 | NTc.Cm23 | LEU 23 | - | VdWContact |
| CYS 7 | NTc.Cm23 | CYS 24 | - | HBAcceptor |
| CYS 7 | NTc.Cm23 | CYS 24 | - | HBDonor |
| CYS 7 | NTc.Cm23 | CYS 24 | - | VdWContact |
| CYS 7 | NTc.Cm23 | LYS 26 | 1.24x24 | Anionic |
| CYS 8 | NTc.Cm22 | LEU 23 | - | Hydrophobic |
| CYS 8 | NTc.Cm22 | LEU 23 | - | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 24 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | ASN 271 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | ASN 271 | - | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 273 | 7.25x24 | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 273 | 7.25x24 | VdWContact |
| LEU 9 | NTc.Cm21 | SER 276 | 7.28x27 | VdWContact |
| ALA 10 | NTc.Cm20 | ASN 271 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | VAL 20 | - | VdWContact |
| HIS 12 | NTc.Cm18 | GLY 21 | - | VdWContact |
| THR 25 | NTc.Cm5 | PHE 178 | - | Hydrophobic |
| ARG 27 | NTc.Cm3 | GLU 175 | - | Cationic |
| ARG 27 | NTc.Cm3 | GLU 175 | - | HBDonor |
| ARG 27 | NTc.Cm3 | GLU 175 | - | VdWContact |
| ARG 27 | NTc.Cm3 | LEU 177 | - | Hydrophobic |
| ARG 27 | NTc.Cm3 | PHE 178 | - | Hydrophobic |
| GLU 30 | CX.1 | LEU 186 | - | Hydrophobic |
| VAL 31 | CX.5 | VAL 192 | 5.31x32 | Hydrophobic |
| VAL 31 | CX.5 | VAL 192 | 5.31x32 | VdWContact |
| VAL 31 | CX.5 | TYR 193 | 5.32x33 | Hydrophobic |
| VAL 31 | CX.5 | ARG 196 | 5.35x36 | HBAcceptor |
| VAL 31 | CX.5 | ARG 196 | 5.35x36 | VdWContact |
| SER 32 | cxb1.1 | SER 184 | 45.51x51 | VdWContact |
| SER 32 | cxb1.1 | ARG 196 | 5.35x36 | VdWContact |
| GLY 33 | cxb1.2 | ARG 196 | 5.35x36 | HBAcceptor |
| GLY 33 | cxb1.2 | ARG 196 | 5.35x36 | VdWContact |
| SER 34 | cxb1.5 | LYS 26 | 1.24x24 | HBAcceptor |
| SER 34 | cxb1.5 | LYS 26 | 1.24x24 | VdWContact |
| ASN 36 | cxb1.8 | TYR 193 | 5.32x33 | HBAcceptor |
| ASN 36 | cxb1.8 | TYR 193 | 5.32x33 | VdWContact |
| ASN 36 | cxb1.8 | ARG 196 | 5.35x36 | HBAcceptor |
| ASN 36 | cxb1.8 | ARG 196 | 5.35x36 | VdWContact |
| ASN 36 | cxb1.8 | SER 262 | 6.58x58 | HBDonor |
| ASN 36 | cxb1.8 | SER 262 | 6.58x58 | VdWContact |
| ILE 41 | cxb1.16 | LEU 23 | - | Hydrophobic |
| TYR 43 | B1.2 | PHE 178 | - | Hydrophobic |
| ARG 49 | b1b2.1 | ASP 18 | - | Cationic |
| ARG 49 | b1b2.1 | ASP 18 | - | HBDonor |
| ARG 49 | b1b2.1 | ASP 18 | - | VdWContact |
| ARG 49 | b1b2.1 | ASP 19 | - | Cationic |
| ARG 49 | b1b2.1 | LEU 22 | - | Hydrophobic |
| LYS 50 | b1b2.2 | LEU 23 | - | HBAcceptor |
| LYS 50 | b1b2.2 | LEU 23 | - | Hydrophobic |
| LYS 50 | b1b2.2 | LEU 23 | - | VdWContact |
| LYS 50 | b1b2.2 | GLU 25 | - | Cationic |
| LYS 50 | b1b2.2 | GLU 25 | - | HBDonor |
| LYS 50 | b1b2.2 | GLU 25 | - | VdWContact |
| VAL 51 | b1b2.3 | LEU 22 | - | Hydrophobic |
| CYS 52 | b1b2.4 | GLY 21 | - | HBDonor |
| CYS 52 | b1b2.4 | GLY 21 | - | VdWContact |
| LYS 56 | b1b2.9 | GLU 189 | - | Cationic |
| LYS 56 | b1b2.9 | GLU 189 | - | VdWContact |
| LYS 56 | b1b2.9 | ASP 190 | - | Cationic |
