Predicted complex interactions
CCL4_HUMAN + CCR3
SUMMARY
- Chemokine
- CCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR3 View partner entry
- Partner description
- UniProt: P51677; Gene: ccr3_human; Family: Chemokine
- Interactions detected
- 94
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm33 | TRP 90 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm33 | TRP 90 | 2.60x60 | VdWContact |
| ALA 1 | NTc.Cm33 | TYR 93 | 2.63x63 | Hydrophobic |
| ALA 1 | NTc.Cm33 | TYR 93 | 2.63x63 | VdWContact |
| ALA 1 | NTc.Cm33 | TYR 172 | 4.64x65 | HBAcceptor |
| ALA 1 | NTc.Cm33 | TYR 172 | 4.64x65 | VdWContact |
| ALA 1 | NTc.Cm33 | CYS 183 | 45.50x50 | Cationic |
| ALA 1 | NTc.Cm33 | CYS 183 | 45.50x50 | HBDonor |
| ALA 1 | NTc.Cm33 | CYS 183 | 45.50x50 | VdWContact |
| PRO 2 | NTc.Cm32 | TRP 90 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TRP 90 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 113 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm32 | GLU 287 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 291 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 291 | 7.43x42 | VdWContact |
| MET 3 | NTc.Cm31 | HIS 199 | 5.38x39 | Hydrophobic |
| MET 3 | NTc.Cm31 | MET 283 | 7.35x34 | Hydrophobic |
| GLY 4 | NTc.Cm30 | MET 33 | 1.31x31 | VdWContact |
| GLY 4 | NTc.Cm30 | GLU 287 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm30 | GLU 287 | 7.39x38 | VdWContact |
| SER 5 | NTc.Cm29 | TYR 41 | 1.39x39 | VdWContact |
| SER 5 | NTc.Cm29 | VAL 94 | 2.64x64 | VdWContact |
| SER 5 | NTc.Cm29 | GLU 287 | 7.39x38 | HBDonor |
| SER 5 | NTc.Cm29 | GLU 287 | 7.39x38 | VdWContact |
| ASP 6 | NTc.Cm28 | ARG 30 | 1.28x28 | Anionic |
| ASP 6 | NTc.Cm28 | ARG 30 | 1.28x28 | HBAcceptor |
| ASP 6 | NTc.Cm28 | ARG 30 | 1.28x28 | VdWContact |
| ASP 6 | NTc.Cm28 | TYR 93 | 2.63x63 | HBAcceptor |
| ASP 6 | NTc.Cm28 | TYR 93 | 2.63x63 | Hydrophobic |
| ASP 6 | NTc.Cm28 | TYR 93 | 2.63x63 | VdWContact |
| ASP 6 | NTc.Cm28 | LEU 182 | - | VdWContact |
| PRO 7 | NTc.Cm27 | ARG 30 | 1.28x28 | Hydrophobic |
| PRO 7 | NTc.Cm27 | MET 33 | 1.31x31 | Hydrophobic |
| PRO 7 | NTc.Cm27 | MET 33 | 1.31x31 | VdWContact |
| PRO 7 | NTc.Cm27 | ASP 280 | 7.32x31 | Hydrophobic |
| PRO 8 | NTc.Cm26 | LYS 26 | 1.24x24 | Hydrophobic |
| PRO 8 | NTc.Cm26 | LYS 26 | 1.24x24 | VdWContact |
| THR 9 | NTc.Cm25 | LYS 26 | 1.24x24 | HBAcceptor |
| THR 9 | NTc.Cm25 | LYS 26 | 1.24x24 | VdWContact |
| ALA 10 | NTc.Cm24 | LEU 23 | - | Hydrophobic |
| ALA 10 | NTc.Cm24 | CYS 24 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 24 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 24 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 24 | - | VdWContact |
| CYS 12 | NTc.Cm22 | LEU 22 | - | VdWContact |
| PHE 13 | NTc.Cm21 | LEU 22 | - | HBDonor |
| PHE 13 | NTc.Cm21 | LEU 22 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | LEU 22 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 24 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 24 | - | VdWContact |
| PHE 13 | NTc.Cm21 | ASN 271 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | ASN 271 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 273 | 7.25x24 | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 273 | 7.25x24 | VdWContact |
| PHE 13 | NTc.Cm21 | SER 276 | 7.28x27 | VdWContact |
| SER 14 | NTc.Cm20 | LEU 22 | - | HBAcceptor |
| SER 14 | NTc.Cm20 | LEU 22 | - | VdWContact |
| THR 16 | NTc.Cm18 | ASP 19 | - | HBDonor |
| THR 16 | NTc.Cm18 | ASP 19 | - | VdWContact |
| ALA 17 | NTc.Cm17 | ASP 19 | - | VdWContact |
| ARG 18 | NTc.Cm16 | TYR 16 | - | HBAcceptor |
| ARG 18 | NTc.Cm16 | TYR 16 | - | Hydrophobic |
| ARG 18 | NTc.Cm16 | TYR 16 | - | VdWContact |
| LYS 19 | NTc.Cm15 | TYR 16 | - | VdWContact |
| LEU 20 | NTc.Cm14 | TYR 16 | - | HBAcceptor |
| LEU 20 | NTc.Cm14 | TYR 16 | - | Hydrophobic |
| LEU 20 | NTc.Cm14 | TYR 16 | - | VdWContact |
| PRO 21 | NTc.Cm13 | TYR 16 | - | VdWContact |
| TYR 29 | NTc.Cm5 | PHE 178 | - | Hydrophobic |
| TYR 29 | NTc.Cm5 | PHE 178 | - | VdWContact |
| GLU 30 | NTc.Cm4 | LEU 177 | - | VdWContact |
| SER 33 | NTc.Cm1 | ALA 185 | 45.52x52 | HBDonor |
| SER 33 | NTc.Cm1 | ALA 185 | 45.52x52 | VdWContact |
| SER 33 | NTc.Cm1 | ARG 196 | 5.35x36 | HBAcceptor |
| SER 33 | NTc.Cm1 | ARG 196 | 5.35x36 | VdWContact |
| CYS 35 | CX.5 | ARG 196 | 5.35x36 | HBAcceptor |
| CYS 35 | CX.5 | ARG 196 | 5.35x36 | VdWContact |
| SER 36 | cxb1.1 | TYR 193 | 5.32x33 | HBAcceptor |
| SER 36 | cxb1.1 | TYR 193 | 5.32x33 | VdWContact |
| GLN 37 | cxb1.2 | TYR 193 | 5.32x33 | VdWContact |
| VAL 41 | cxb1.8 | LEU 23 | - | Hydrophobic |
| THR 44 | cxb1.14 | TYR 17 | - | Hydrophobic |
| ARG 46 | cxb1.16 | TYR 17 | - | Hydrophobic |
| ARG 46 | cxb1.16 | TYR 17 | - | VdWContact |
| LYS 48 | B1.2 | TYR 17 | - | Hydrophobic |
| LYS 48 | B1.2 | TYR 17 | - | VdWContact |
| GLN 49 | B1.3 | VAL 20 | - | VdWContact |
| GLN 49 | B1.3 | LEU 23 | - | Hydrophobic |
| GLN 49 | B1.3 | LEU 23 | - | VdWContact |
| VAL 50 | B1.4 | VAL 20 | - | Hydrophobic |
| VAL 50 | B1.4 | VAL 20 | - | VdWContact |
| CYS 51 | B1.5 | VAL 20 | - | HBDonor |
| CYS 51 | B1.5 | VAL 20 | - | VdWContact |
| CYS 51 | B1.5 | GLY 21 | - | VdWContact |
