Predicted complex interactions
CCL5_HUMAN + CCR3
SUMMARY
- Chemokine
- CCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR3 View partner entry
- Partner description
- UniProt: P51677; Gene: ccr3_human; Family: Chemokine
- Interactions detected
- 79
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm32 | GLU 287 | 7.39x38 | HBDonor |
| SER 1 | NTc.Cm32 | GLU 287 | 7.39x38 | VdWContact |
| SER 1 | NTc.Cm32 | TYR 291 | 7.43x42 | VdWContact |
| PRO 2 | NTc.Cm31 | TYR 113 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm31 | HIS 114 | 3.33x33 | Hydrophobic |
| PRO 2 | NTc.Cm31 | TYR 172 | 4.64x65 | Hydrophobic |
| PRO 2 | NTc.Cm31 | TYR 172 | 4.64x65 | VdWContact |
| TYR 3 | NTc.Cm30 | HIS 199 | 5.38x39 | HBDonor |
| TYR 3 | NTc.Cm30 | HIS 199 | 5.38x39 | Hydrophobic |
| TYR 3 | NTc.Cm30 | HIS 199 | 5.38x39 | VdWContact |
| TYR 3 | NTc.Cm30 | ILE 259 | 6.55x55 | Hydrophobic |
| TYR 3 | NTc.Cm30 | MET 283 | 7.35x34 | Hydrophobic |
| SER 4 | NTc.Cm29 | MET 33 | 1.31x31 | VdWContact |
| SER 5 | NTc.Cm28 | TYR 93 | 2.63x63 | VdWContact |
| ASP 6 | NTc.Cm27 | LYS 26 | 1.24x24 | HBAcceptor |
| ASP 6 | NTc.Cm27 | LYS 26 | 1.24x24 | VdWContact |
| THR 7 | NTc.Cm26 | THR 29 | 1.27x27 | Hydrophobic |
| THR 7 | NTc.Cm26 | ARG 30 | 1.28x28 | HBAcceptor |
| THR 7 | NTc.Cm26 | ARG 30 | 1.28x28 | VdWContact |
| THR 7 | NTc.Cm26 | MET 33 | 1.31x31 | Hydrophobic |
| THR 7 | NTc.Cm26 | MET 33 | 1.31x31 | VdWContact |
| THR 7 | NTc.Cm26 | ASP 280 | 7.32x31 | Hydrophobic |
| THR 8 | NTc.Cm25 | ARG 30 | 1.28x28 | VdWContact |
| PRO 9 | NTc.Cm24 | LEU 23 | - | Hydrophobic |
| PRO 9 | NTc.Cm24 | LEU 23 | - | VdWContact |
| PRO 9 | NTc.Cm24 | CYS 24 | - | VdWContact |
| PRO 9 | NTc.Cm24 | ARG 30 | 1.28x28 | VdWContact |
| PRO 9 | NTc.Cm24 | LEU 177 | - | Hydrophobic |
| CYS 10 | NTc.Cm23 | LEU 23 | - | VdWContact |
| CYS 10 | NTc.Cm23 | CYS 24 | - | HBAcceptor |
| CYS 10 | NTc.Cm23 | CYS 24 | - | VdWContact |
| CYS 11 | NTc.Cm22 | LEU 23 | - | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 24 | - | Hydrophobic |
| PHE 12 | NTc.Cm21 | CYS 24 | - | VdWContact |
| PHE 12 | NTc.Cm21 | ASN 271 | - | Hydrophobic |
| PHE 12 | NTc.Cm21 | ASN 271 | - | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 273 | 7.25x24 | Hydrophobic |
| PHE 12 | NTc.Cm21 | SER 276 | 7.28x27 | VdWContact |
| ARG 17 | NTc.Cm16 | TYR 16 | - | Hydrophobic |
| PRO 18 | NTc.Cm15 | TYR 16 | - | HBAcceptor |
| PRO 18 | NTc.Cm15 | TYR 16 | - | VdWContact |
| LEU 19 | NTc.Cm14 | TYR 16 | - | Hydrophobic |
| LEU 19 | NTc.Cm14 | TYR 17 | - | Hydrophobic |
| GLU 26 | NTc.Cm7 | PHE 178 | - | Hydrophobic |
| GLU 26 | NTc.Cm7 | PHE 178 | - | VdWContact |
| PHE 28 | NTc.Cm5 | LEU 23 | - | Hydrophobic |
| PHE 28 | NTc.Cm5 | LEU 23 | - | VdWContact |
| PHE 28 | NTc.Cm5 | LEU 177 | - | Hydrophobic |
| PHE 28 | NTc.Cm5 | PHE 178 | - | Hydrophobic |
| PHE 28 | NTc.Cm5 | PHE 178 | - | PiStacking |
| PHE 28 | NTc.Cm5 | PHE 178 | - | VdWContact |
| TYR 29 | NTc.Cm4 | LEU 177 | - | VdWContact |
| THR 30 | NTc.Cm3 | LEU 23 | - | Hydrophobic |
| SER 31 | NTc.Cm2 | GLU 175 | - | HBDonor |
| SER 31 | NTc.Cm2 | GLU 175 | - | VdWContact |
| GLY 32 | NTc.Cm1 | GLU 175 | - | HBDonor |
| GLY 32 | NTc.Cm1 | GLU 175 | - | VdWContact |
| GLY 32 | NTc.Cm1 | ARG 196 | 5.35x36 | HBAcceptor |
| GLY 32 | NTc.Cm1 | ARG 196 | 5.35x36 | VdWContact |
| LYS 33 | CX.1 | SER 184 | 45.51x51 | VdWContact |
| LYS 33 | CX.1 | ARG 196 | 5.35x36 | VdWContact |
| CYS 34 | CX.5 | ARG 196 | 5.35x36 | HBAcceptor |
| CYS 34 | CX.5 | ARG 196 | 5.35x36 | VdWContact |
| SER 35 | cxb1.1 | TYR 193 | 5.32x33 | HBAcceptor |
| SER 35 | cxb1.1 | TYR 193 | 5.32x33 | VdWContact |
| SER 35 | cxb1.1 | ARG 196 | 5.35x36 | VdWContact |
| ASN 36 | cxb1.2 | ASN 271 | - | VdWContact |
| VAL 40 | cxb1.8 | LEU 23 | - | Hydrophobic |
| VAL 40 | cxb1.8 | LEU 23 | - | VdWContact |
| VAL 42 | cxb1.11 | PHE 178 | - | Hydrophobic |
| THR 43 | cxb1.14 | TYR 17 | - | VdWContact |
| ARG 47 | B1.2 | TYR 17 | - | VdWContact |
| GLN 48 | B1.3 | LEU 23 | - | HBAcceptor |
| GLN 48 | B1.3 | LEU 23 | - | Hydrophobic |
| GLN 48 | B1.3 | LEU 23 | - | VdWContact |
| VAL 49 | B1.4 | TYR 17 | - | Hydrophobic |
| CYS 50 | B1.5 | GLY 21 | - | HBDonor |
| CYS 50 | B1.5 | GLY 21 | - | VdWContact |
| CYS 50 | B1.5 | LEU 23 | - | VdWContact |
