Predicted complex interactions
CCL8_HUMAN + CCR3
SUMMARY
- Chemokine
- CCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR3 View partner entry
- Partner description
- UniProt: P51677; Gene: ccr3_human; Family: Chemokine
- Interactions detected
- 91
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | ARG 196 | 5.35x36 | Hydrophobic |
| GLN 1 | NTc.Cm33 | ARG 196 | 5.35x36 | VdWContact |
| PRO 2 | NTc.Cm32 | HIS 199 | 5.38x39 | Hydrophobic |
| PRO 2 | NTc.Cm32 | HIS 199 | 5.38x39 | VdWContact |
| PRO 2 | NTc.Cm32 | MET 203 | 5.42x43 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 255 | 6.51x51 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 255 | 6.51x51 | VdWContact |
| PRO 2 | NTc.Cm32 | ILE 259 | 6.55x55 | Hydrophobic |
| PRO 2 | NTc.Cm32 | ILE 259 | 6.55x55 | VdWContact |
| ASP 3 | NTc.Cm31 | TYR 172 | 4.64x65 | VdWContact |
| SER 4 | NTc.Cm30 | TRP 90 | 2.60x60 | VdWContact |
| SER 4 | NTc.Cm30 | TYR 113 | 3.32x32 | VdWContact |
| SER 4 | NTc.Cm30 | TYR 172 | 4.64x65 | VdWContact |
| SER 4 | NTc.Cm30 | TYR 291 | 7.43x42 | VdWContact |
| VAL 5 | NTc.Cm29 | TYR 41 | 1.39x39 | Hydrophobic |
| VAL 5 | NTc.Cm29 | TYR 41 | 1.39x39 | VdWContact |
| VAL 5 | NTc.Cm29 | TRP 90 | 2.60x60 | Hydrophobic |
| VAL 5 | NTc.Cm29 | TRP 90 | 2.60x60 | VdWContact |
| VAL 5 | NTc.Cm29 | VAL 94 | 2.64x64 | Hydrophobic |
| VAL 5 | NTc.Cm29 | VAL 94 | 2.64x64 | VdWContact |
| VAL 5 | NTc.Cm29 | GLU 287 | 7.39x38 | VdWContact |
| SER 6 | NTc.Cm28 | GLU 287 | 7.39x38 | HBDonor |
| SER 6 | NTc.Cm28 | GLU 287 | 7.39x38 | VdWContact |
| ILE 7 | NTc.Cm27 | TYR 93 | 2.63x63 | Hydrophobic |
| ILE 7 | NTc.Cm27 | TYR 93 | 2.63x63 | VdWContact |
| ILE 7 | NTc.Cm27 | VAL 94 | 2.64x64 | Hydrophobic |
| PRO 8 | NTc.Cm26 | LYS 26 | 1.24x24 | Hydrophobic |
| PRO 8 | NTc.Cm26 | THR 29 | 1.27x27 | Hydrophobic |
| PRO 8 | NTc.Cm26 | ARG 30 | 1.28x28 | HBAcceptor |
| PRO 8 | NTc.Cm26 | ARG 30 | 1.28x28 | Hydrophobic |
| PRO 8 | NTc.Cm26 | ARG 30 | 1.28x28 | VdWContact |
| PRO 8 | NTc.Cm26 | MET 33 | 1.31x31 | Hydrophobic |
| PRO 8 | NTc.Cm26 | MET 33 | 1.31x31 | VdWContact |
| PRO 8 | NTc.Cm26 | ASP 280 | 7.32x31 | Hydrophobic |
| PRO 8 | NTc.Cm26 | ASP 280 | 7.32x31 | VdWContact |
| ILE 9 | NTc.Cm25 | LEU 182 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | LEU 23 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | LEU 23 | - | VdWContact |
| THR 10 | NTc.Cm24 | CYS 24 | - | VdWContact |
| THR 10 | NTc.Cm24 | GLU 25 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | PHE 178 | - | Hydrophobic |
| CYS 11 | NTc.Cm23 | CYS 24 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 24 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 24 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 24 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 24 | - | VdWContact |
| PHE 13 | NTc.Cm21 | ASN 271 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | ASN 271 | - | VdWContact |
| PHE 13 | NTc.Cm21 | SER 276 | 7.28x27 | VdWContact |
| ASN 14 | NTc.Cm20 | VAL 20 | - | Hydrophobic |
| ASN 14 | NTc.Cm20 | VAL 20 | - | VdWContact |
| ARG 18 | NTc.Cm16 | TYR 16 | - | CationPi |
| ARG 18 | NTc.Cm16 | TYR 16 | - | HBDonor |
| ARG 18 | NTc.Cm16 | TYR 16 | - | VdWContact |
| ARG 18 | NTc.Cm16 | ASP 19 | - | Cationic |
| ARG 18 | NTc.Cm16 | ASP 19 | - | HBDonor |
| ARG 18 | NTc.Cm16 | ASP 19 | - | VdWContact |
| THR 29 | NTc.Cm5 | LEU 177 | - | Hydrophobic |
| ARG 30 | NTc.Cm4 | GLU 189 | - | Cationic |
| ARG 30 | NTc.Cm4 | GLU 189 | - | HBDonor |
| ARG 30 | NTc.Cm4 | GLU 189 | - | VdWContact |
| ILE 31 | NTc.Cm3 | LEU 177 | - | Hydrophobic |
| THR 32 | NTc.Cm2 | GLU 189 | - | Hydrophobic |
| ASN 33 | NTc.Cm1 | GLU 175 | - | HBDonor |
| ASN 33 | NTc.Cm1 | GLU 175 | - | VdWContact |
| ASN 33 | NTc.Cm1 | SER 184 | 45.51x51 | HBDonor |
| ASN 33 | NTc.Cm1 | SER 184 | 45.51x51 | VdWContact |
| ILE 34 | CX.1 | ALA 185 | 45.52x52 | Hydrophobic |
| ILE 34 | CX.1 | ALA 185 | 45.52x52 | VdWContact |
| ILE 34 | CX.1 | TYR 187 | - | Hydrophobic |
| ILE 34 | CX.1 | TYR 187 | - | VdWContact |
| GLN 35 | CX.5 | ARG 196 | 5.35x36 | HBAcceptor |
| GLN 35 | CX.5 | ARG 196 | 5.35x36 | VdWContact |
| CYS 36 | cxb1.1 | ARG 196 | 5.35x36 | VdWContact |
| GLU 39 | cxb1.6 | ASP 190 | - | HBAcceptor |
| GLU 39 | cxb1.6 | ASP 190 | - | VdWContact |
| GLU 39 | cxb1.6 | VAL 192 | 5.31x32 | Hydrophobic |
| GLU 39 | cxb1.6 | VAL 192 | 5.31x32 | VdWContact |
| ILE 42 | cxb1.10 | LEU 23 | - | Hydrophobic |
| ILE 42 | cxb1.10 | LEU 23 | - | VdWContact |
| ILE 42 | cxb1.10 | PHE 178 | - | Hydrophobic |
| ILE 42 | cxb1.10 | PHE 178 | - | VdWContact |
| LYS 49 | B1.3 | TYR 17 | - | HBDonor |
| LYS 49 | B1.3 | TYR 17 | - | VdWContact |
| GLU 50 | B1.4 | LEU 23 | - | Hydrophobic |
| GLU 50 | B1.4 | PHE 178 | - | VdWContact |
| VAL 51 | B1.5 | GLY 21 | - | VdWContact |
| CYS 52 | B1.6 | GLY 21 | - | HBDonor |
| CYS 52 | B1.6 | GLY 21 | - | VdWContact |
| CYS 52 | B1.6 | LEU 23 | - | VdWContact |
| LYS 56 | b1b2.7 | ASP 190 | - | Cationic |
