Predicted complex interactions
CXCL10_HUMAN + CCR3
SUMMARY
- Chemokine
- CXCL10_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR3 View partner entry
- Partner description
- UniProt: P51677; Gene: ccr3_human; Family: Chemokine
- Interactions detected
- 101
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm29 | TRP 90 | 2.60x60 | Hydrophobic |
| VAL 1 | NTc.Cm29 | TRP 90 | 2.60x60 | VdWContact |
| VAL 1 | NTc.Cm29 | TYR 113 | 3.32x32 | Hydrophobic |
| VAL 1 | NTc.Cm29 | TYR 113 | 3.32x32 | VdWContact |
| VAL 1 | NTc.Cm29 | HIS 114 | 3.33x33 | Hydrophobic |
| VAL 1 | NTc.Cm29 | HIS 114 | 3.33x33 | VdWContact |
| VAL 1 | NTc.Cm29 | TYR 172 | 4.64x65 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TYR 41 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TYR 41 | 1.39x39 | VdWContact |
| PRO 2 | NTc.Cm28 | TRP 90 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TRP 90 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm28 | TYR 113 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TYR 113 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm28 | GLU 287 | 7.39x38 | VdWContact |
| LEU 3 | NTc.Cm27 | MET 283 | 7.35x34 | Hydrophobic |
| LEU 3 | NTc.Cm27 | MET 283 | 7.35x34 | VdWContact |
| LEU 3 | NTc.Cm27 | LEU 284 | 7.36x35 | Hydrophobic |
| LEU 3 | NTc.Cm27 | LEU 284 | 7.36x35 | VdWContact |
| LEU 3 | NTc.Cm27 | GLU 287 | 7.39x38 | HBDonor |
| LEU 3 | NTc.Cm27 | GLU 287 | 7.39x38 | Hydrophobic |
| LEU 3 | NTc.Cm27 | GLU 287 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm26 | TYR 93 | 2.63x63 | VdWContact |
| ARG 5 | NTc.Cm25 | HIS 97 | 2.67x67 | HBDonor |
| ARG 5 | NTc.Cm25 | HIS 97 | 2.67x67 | VdWContact |
| ARG 5 | NTc.Cm25 | LEU 177 | - | VdWContact |
| ARG 5 | NTc.Cm25 | GLU 180 | - | Cationic |
| ARG 5 | NTc.Cm25 | GLU 180 | - | HBDonor |
| ARG 5 | NTc.Cm25 | GLU 180 | - | VdWContact |
| ARG 5 | NTc.Cm25 | LEU 182 | - | Hydrophobic |
| ARG 5 | NTc.Cm25 | LEU 182 | - | VdWContact |
| VAL 7 | NTc.Cm23 | LYS 26 | 1.24x24 | Hydrophobic |
| VAL 7 | NTc.Cm23 | LYS 26 | 1.24x24 | VdWContact |
| VAL 7 | NTc.Cm23 | ARG 30 | 1.28x28 | Hydrophobic |
| VAL 7 | NTc.Cm23 | ARG 30 | 1.28x28 | VdWContact |
| VAL 7 | NTc.Cm23 | MET 33 | 1.31x31 | Hydrophobic |
| ARG 8 | NTc.Cm22 | LYS 26 | 1.24x24 | VdWContact |
| ARG 8 | NTc.Cm22 | SER 262 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm22 | GLN 265 | 6.61x61 | HBDonor |
| ARG 8 | NTc.Cm22 | GLN 265 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm22 | SER 276 | 7.28x27 | HBDonor |
| ARG 8 | NTc.Cm22 | SER 276 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm22 | LEU 279 | 7.31x30 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 280 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 280 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm22 | ASP 280 | 7.32x31 | VdWContact |
| THR 10 | NTc.Cm20 | LEU 23 | - | VdWContact |
| THR 10 | NTc.Cm20 | CYS 24 | - | HBAcceptor |
| THR 10 | NTc.Cm20 | CYS 24 | - | VdWContact |
| ILE 12 | NTc.Cm18 | LEU 22 | - | HBDonor |
| ILE 12 | NTc.Cm18 | LEU 22 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | LEU 22 | - | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 24 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | CYS 24 | - | VdWContact |
| ILE 12 | NTc.Cm18 | ASN 271 | - | HBAcceptor |
| ILE 12 | NTc.Cm18 | ASN 271 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | ASN 271 | - | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 273 | 7.25x24 | Hydrophobic |
| ILE 12 | NTc.Cm18 | CYS 273 | 7.25x24 | VdWContact |
| SER 13 | NTc.Cm17 | VAL 20 | - | VdWContact |
| SER 13 | NTc.Cm17 | LEU 22 | - | HBAcceptor |
| SER 13 | NTc.Cm17 | LEU 22 | - | VdWContact |
| SER 15 | NTc.Cm15 | ASP 19 | - | HBDonor |
| SER 15 | NTc.Cm15 | ASP 19 | - | VdWContact |
| SER 15 | NTc.Cm15 | GLY 21 | - | VdWContact |
| ASN 16 | NTc.Cm14 | ASP 19 | - | HBDonor |
| ASN 16 | NTc.Cm14 | ASP 19 | - | VdWContact |
| GLN 17 | NTc.Cm13 | ASP 19 | - | HBDonor |
| GLN 17 | NTc.Cm13 | ASP 19 | - | VdWContact |
| LYS 26 | NTc.Cm4 | PHE 178 | - | Hydrophobic |
| LYS 26 | NTc.Cm4 | PHE 178 | - | VdWContact |
| GLU 28 | NTc.Cm2 | PHE 178 | - | Hydrophobic |
| GLU 28 | NTc.Cm2 | PHE 178 | - | VdWContact |
| ILE 30 | CX.1 | LEU 177 | - | Hydrophobic |
| PRO 31 | CX.4 | GLU 175 | - | Hydrophobic |
| PRO 31 | CX.4 | GLU 175 | - | VdWContact |
| PRO 31 | CX.4 | LEU 186 | - | Hydrophobic |
| ALA 32 | CX.5 | VAL 192 | 5.31x32 | Hydrophobic |
| ALA 32 | CX.5 | VAL 192 | 5.31x32 | VdWContact |
| SER 33 | cxb1.1 | ALA 185 | 45.52x52 | VdWContact |
| GLN 34 | cxb1.2 | TYR 172 | 4.64x65 | HBAcceptor |
| GLN 34 | cxb1.2 | TYR 172 | 4.64x65 | VdWContact |
| GLN 34 | cxb1.2 | ALA 185 | 45.52x52 | HBDonor |
| GLN 34 | cxb1.2 | ALA 185 | 45.52x52 | Hydrophobic |
| GLN 34 | cxb1.2 | ALA 185 | 45.52x52 | VdWContact |
| GLN 34 | cxb1.2 | TYR 187 | - | Hydrophobic |
| GLN 34 | cxb1.2 | TYR 187 | - | VdWContact |
| GLN 34 | cxb1.2 | ARG 196 | 5.35x36 | HBAcceptor |
| GLN 34 | cxb1.2 | ARG 196 | 5.35x36 | VdWContact |
| GLN 34 | cxb1.2 | HIS 199 | 5.38x39 | VdWContact |
| PHE 35 | cxb1.5 | ARG 196 | 5.35x36 | HBAcceptor |
| PHE 35 | cxb1.5 | ARG 196 | 5.35x36 | VdWContact |
| PRO 37 | cxb1.7 | VAL 192 | 5.31x32 | Hydrophobic |
| PRO 37 | cxb1.7 | VAL 192 | 5.31x32 | VdWContact |
| PRO 37 | cxb1.7 | TYR 193 | 5.32x33 | Hydrophobic |
| PRO 37 | cxb1.7 | ARG 196 | 5.35x36 | VdWContact |
| ARG 38 | cxb1.8 | ASN 271 | - | VdWContact |
| ILE 42 | cxb1.15 | LEU 23 | - | Hydrophobic |
| LYS 51 | b1b2.4 | LEU 23 | - | Hydrophobic |
| ARG 52 | b1b2.6 | GLY 21 | - | VdWContact |
| CYS 53 | b1b2.7 | GLY 21 | - | HBDonor |
| CYS 53 | b1b2.7 | GLY 21 | - | VdWContact |
