Predicted complex interactions
CXCL11_HUMAN + CCR3
SUMMARY
- Chemokine
- CXCL11_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR3 View partner entry
- Partner description
- UniProt: P51677; Gene: ccr3_human; Family: Chemokine
- Interactions detected
- 127
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PHE 1 | NTc.Cm29 | TRP 90 | 2.60x60 | Hydrophobic |
| PHE 1 | NTc.Cm29 | TRP 90 | 2.60x60 | VdWContact |
| PHE 1 | NTc.Cm29 | TYR 113 | 3.32x32 | Hydrophobic |
| PHE 1 | NTc.Cm29 | TYR 113 | 3.32x32 | PiStacking |
| PHE 1 | NTc.Cm29 | TYR 113 | 3.32x32 | VdWContact |
| PHE 1 | NTc.Cm29 | HIS 114 | 3.33x33 | Hydrophobic |
| PHE 1 | NTc.Cm29 | HIS 114 | 3.33x33 | VdWContact |
| PHE 1 | NTc.Cm29 | TYR 172 | 4.64x65 | Hydrophobic |
| PHE 1 | NTc.Cm29 | GLU 287 | 7.39x38 | Cationic |
| PHE 1 | NTc.Cm29 | GLU 287 | 7.39x38 | HBDonor |
| PHE 1 | NTc.Cm29 | GLU 287 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm28 | TRP 90 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TRP 90 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm28 | TYR 93 | 2.63x63 | VdWContact |
| PRO 2 | NTc.Cm28 | VAL 94 | 2.64x64 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TYR 113 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TYR 113 | 3.32x32 | VdWContact |
| MET 3 | NTc.Cm27 | TYR 172 | 4.64x65 | Hydrophobic |
| MET 3 | NTc.Cm27 | TYR 172 | 4.64x65 | VdWContact |
| MET 3 | NTc.Cm27 | ALA 185 | 45.52x52 | Hydrophobic |
| MET 3 | NTc.Cm27 | ALA 185 | 45.52x52 | VdWContact |
| PHE 4 | NTc.Cm26 | MET 33 | 1.31x31 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ASP 280 | 7.32x31 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ASP 280 | 7.32x31 | VdWContact |
| PHE 4 | NTc.Cm26 | MET 283 | 7.35x34 | Hydrophobic |
| PHE 4 | NTc.Cm26 | MET 283 | 7.35x34 | VdWContact |
| LYS 5 | NTc.Cm25 | ARG 30 | 1.28x28 | HBAcceptor |
| LYS 5 | NTc.Cm25 | ARG 30 | 1.28x28 | VdWContact |
| LYS 5 | NTc.Cm25 | TYR 93 | 2.63x63 | CationPi |
| LYS 5 | NTc.Cm25 | TYR 93 | 2.63x63 | HBDonor |
| LYS 5 | NTc.Cm25 | TYR 93 | 2.63x63 | Hydrophobic |
| LYS 5 | NTc.Cm25 | TYR 93 | 2.63x63 | VdWContact |
| LYS 5 | NTc.Cm25 | VAL 94 | 2.64x64 | VdWContact |
| LYS 5 | NTc.Cm25 | HIS 97 | 2.67x67 | HBDonor |
| LYS 5 | NTc.Cm25 | HIS 97 | 2.67x67 | VdWContact |
| LYS 5 | NTc.Cm25 | LEU 182 | - | Hydrophobic |
| ARG 6 | NTc.Cm24 | GLU 175 | - | Cationic |
| ARG 6 | NTc.Cm24 | GLU 175 | - | HBDonor |
| ARG 6 | NTc.Cm24 | GLU 175 | - | VdWContact |
| ARG 6 | NTc.Cm24 | LEU 182 | - | Hydrophobic |
| ARG 8 | NTc.Cm22 | LYS 26 | 1.24x24 | HBAcceptor |
| ARG 8 | NTc.Cm22 | LYS 26 | 1.24x24 | VdWContact |
| ARG 8 | NTc.Cm22 | SER 262 | 6.58x58 | HBDonor |
| ARG 8 | NTc.Cm22 | SER 262 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm22 | GLN 265 | 6.61x61 | HBDonor |
| ARG 8 | NTc.Cm22 | GLN 265 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm22 | SER 276 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm22 | LEU 279 | 7.31x30 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 280 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 280 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm22 | ASP 280 | 7.32x31 | VdWContact |
| LEU 10 | NTc.Cm20 | LEU 23 | - | Hydrophobic |
| LEU 10 | NTc.Cm20 | CYS 24 | - | HBAcceptor |
| LEU 10 | NTc.Cm20 | CYS 24 | - | VdWContact |
| LEU 10 | NTc.Cm20 | LYS 26 | 1.24x24 | Hydrophobic |
| LEU 10 | NTc.Cm20 | LEU 177 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | CYS 24 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | CYS 24 | - | VdWContact |
| ILE 12 | NTc.Cm18 | ASN 271 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | ASN 271 | - | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 273 | 7.25x24 | Hydrophobic |
| PRO 14 | NTc.Cm16 | VAL 20 | - | Hydrophobic |
| PRO 14 | NTc.Cm16 | VAL 20 | - | VdWContact |
| GLY 15 | NTc.Cm15 | VAL 20 | - | HBDonor |
| GLY 15 | NTc.Cm15 | VAL 20 | - | VdWContact |
| LYS 17 | NTc.Cm13 | THR 14 | - | VdWContact |
| ALA 18 | NTc.Cm12 | PHE 11 | - | Hydrophobic |
| ALA 18 | NTc.Cm12 | PHE 11 | - | VdWContact |
| LYS 20 | NTc.Cm10 | THR 13 | - | Hydrophobic |
| LYS 20 | NTc.Cm10 | THR 13 | - | VdWContact |
| VAL 21 | NTc.Cm9 | LEU 5 | - | Hydrophobic |
| LYS 26 | NTc.Cm4 | GLU 176 | - | Cationic |
| LYS 26 | NTc.Cm4 | PHE 178 | - | HBDonor |
| LYS 26 | NTc.Cm4 | PHE 178 | - | VdWContact |
| SER 28 | NTc.Cm2 | PHE 178 | - | HBAcceptor |
| SER 28 | NTc.Cm2 | PHE 178 | - | VdWContact |
| MET 30 | CX.1 | LEU 177 | - | Hydrophobic |
| MET 30 | CX.1 | LEU 177 | - | VdWContact |
| MET 30 | CX.1 | LEU 182 | - | Hydrophobic |
| TYR 31 | CX.4 | LEU 186 | - | Hydrophobic |
| PRO 32 | CX.5 | LEU 186 | - | VdWContact |
| PRO 32 | CX.5 | TYR 187 | - | HBAcceptor |
| PRO 32 | CX.5 | TYR 187 | - | VdWContact |
| PRO 32 | CX.5 | GLU 189 | - | Hydrophobic |
| PRO 32 | CX.5 | GLU 189 | - | VdWContact |
| PRO 32 | CX.5 | VAL 192 | 5.31x32 | Hydrophobic |
| PRO 32 | CX.5 | VAL 192 | 5.31x32 | VdWContact |
| SER 33 | cxb1.1 | ALA 185 | 45.52x52 | VdWContact |
| SER 33 | cxb1.1 | ARG 196 | 5.35x36 | VdWContact |
| ASN 34 | cxb1.2 | TYR 187 | - | Hydrophobic |
| ASN 34 | cxb1.2 | TYR 187 | - | VdWContact |
| ASN 34 | cxb1.2 | ARG 196 | 5.35x36 | HBAcceptor |
| ASN 34 | cxb1.2 | ARG 196 | 5.35x36 | VdWContact |
| ASP 37 | cxb1.7 | VAL 192 | 5.31x32 | VdWContact |
| ASP 37 | cxb1.7 | ARG 196 | 5.35x36 | Anionic |
| ASP 37 | cxb1.7 | ARG 196 | 5.35x36 | VdWContact |
| ILE 39 | cxb1.10 | GLU 189 | - | VdWContact |
| ILE 42 | cxb1.15 | LEU 23 | - | Hydrophobic |
| ILE 42 | cxb1.15 | LEU 23 | - | VdWContact |
| ILE 42 | cxb1.15 | LEU 177 | - | Hydrophobic |
| ILE 42 | cxb1.15 | PHE 178 | - | Hydrophobic |
| ILE 42 | cxb1.15 | PHE 178 | - | VdWContact |
| LEU 45 | B1.2 | TYR 16 | - | Hydrophobic |
| LEU 45 | B1.2 | TYR 16 | - | VdWContact |
| LYS 49 | B1.6 | TYR 16 | - | HBAcceptor |
| LYS 49 | B1.6 | TYR 16 | - | Hydrophobic |
| LYS 49 | B1.6 | TYR 16 | - | VdWContact |
| GLN 51 | b1b2.4 | LEU 23 | - | Hydrophobic |
| GLN 51 | b1b2.4 | LEU 23 | - | VdWContact |
| GLN 51 | b1b2.4 | PHE 178 | - | Hydrophobic |
| GLN 51 | b1b2.4 | PHE 178 | - | VdWContact |
| ARG 52 | b1b2.6 | TYR 16 | - | HBDonor |
| ARG 52 | b1b2.6 | TYR 16 | - | VdWContact |
| ARG 52 | b1b2.6 | GLY 21 | - | VdWContact |
| CYS 53 | b1b2.7 | GLY 21 | - | HBDonor |
| CYS 53 | b1b2.7 | GLY 21 | - | VdWContact |
| CYS 53 | b1b2.7 | LEU 23 | - | VdWContact |
| LYS 59 | b1b2.14 | GLU 9 | - | Cationic |
| LYS 59 | b1b2.14 | PHE 11 | - | Hydrophobic |
| LYS 59 | b1b2.14 | PHE 11 | - | VdWContact |
| GLN 60 | b1b2.16 | PHE 11 | - | Hydrophobic |
| LEU 63 | B2.3 | PHE 11 | - | Hydrophobic |
| LEU 63 | B2.3 | PHE 11 | - | VdWContact |
| LYS 67 | b2b3.2 | THR 3 | - | HBDonor |
| LYS 67 | b2b3.2 | THR 3 | - | VdWContact |
| LYS 67 | b2b3.2 | LEU 5 | - | Hydrophobic |
| LYS 67 | b2b3.2 | LEU 5 | - | VdWContact |
