Predicted complex interactions
CXCL3_HUMAN + CCR3
SUMMARY
- Chemokine
- CXCL3_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR3 View partner entry
- Partner description
- UniProt: P51677; Gene: ccr3_human; Family: Chemokine
- Interactions detected
- 105
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm42 | HIS 199 | 5.38x39 | HBDonor |
| ALA 1 | NTc.Cm42 | HIS 199 | 5.38x39 | Hydrophobic |
| ALA 1 | NTc.Cm42 | HIS 199 | 5.38x39 | VdWContact |
| SER 2 | NTc.Cm41 | TYR 113 | 3.32x32 | VdWContact |
| SER 2 | NTc.Cm41 | TYR 255 | 6.51x51 | VdWContact |
| SER 2 | NTc.Cm41 | GLU 287 | 7.39x38 | HBDonor |
| SER 2 | NTc.Cm41 | GLU 287 | 7.39x38 | VdWContact |
| SER 2 | NTc.Cm41 | TYR 291 | 7.43x42 | VdWContact |
| VAL 3 | NTc.Cm40 | TYR 41 | 1.39x39 | HBAcceptor |
| VAL 3 | NTc.Cm40 | TYR 41 | 1.39x39 | VdWContact |
| VAL 3 | NTc.Cm40 | TRP 90 | 2.60x60 | Hydrophobic |
| VAL 3 | NTc.Cm40 | TRP 90 | 2.60x60 | VdWContact |
| VAL 3 | NTc.Cm40 | TYR 113 | 3.32x32 | Hydrophobic |
| VAL 3 | NTc.Cm40 | TYR 113 | 3.32x32 | VdWContact |
| VAL 3 | NTc.Cm40 | HIS 114 | 3.33x33 | Hydrophobic |
| VAL 4 | NTc.Cm39 | VAL 37 | 1.35x35 | Hydrophobic |
| VAL 4 | NTc.Cm39 | VAL 37 | 1.35x35 | VdWContact |
| VAL 4 | NTc.Cm39 | TYR 41 | 1.39x39 | Hydrophobic |
| VAL 4 | NTc.Cm39 | TYR 41 | 1.39x39 | VdWContact |
| VAL 4 | NTc.Cm39 | TRP 90 | 2.60x60 | Hydrophobic |
| VAL 4 | NTc.Cm39 | TRP 90 | 2.60x60 | VdWContact |
| VAL 4 | NTc.Cm39 | VAL 94 | 2.64x64 | Hydrophobic |
| VAL 4 | NTc.Cm39 | VAL 94 | 2.64x64 | VdWContact |
| VAL 4 | NTc.Cm39 | LEU 284 | 7.36x35 | Hydrophobic |
| THR 5 | NTc.Cm38 | MET 33 | 1.31x31 | Hydrophobic |
| THR 5 | NTc.Cm38 | MET 33 | 1.31x31 | VdWContact |
| THR 5 | NTc.Cm38 | TYR 93 | 2.63x63 | VdWContact |
| THR 5 | NTc.Cm38 | VAL 94 | 2.64x64 | Hydrophobic |
| THR 5 | NTc.Cm38 | VAL 94 | 2.64x64 | VdWContact |
| GLU 6 | NTc.Cm37 | LEU 182 | - | VdWContact |
| GLU 6 | NTc.Cm37 | SER 184 | 45.51x51 | HBAcceptor |
| GLU 6 | NTc.Cm37 | SER 184 | 45.51x51 | VdWContact |
| LEU 7 | NTc.Cm36 | LYS 26 | 1.24x24 | Hydrophobic |
| LEU 7 | NTc.Cm36 | THR 29 | 1.27x27 | Hydrophobic |
| LEU 7 | NTc.Cm36 | ARG 30 | 1.28x28 | Hydrophobic |
| LEU 7 | NTc.Cm36 | ARG 30 | 1.28x28 | VdWContact |
| LEU 7 | NTc.Cm36 | MET 33 | 1.31x31 | Hydrophobic |
| LEU 7 | NTc.Cm36 | ASP 280 | 7.32x31 | Hydrophobic |
| ARG 8 | NTc.Cm35 | LYS 26 | 1.24x24 | HBAcceptor |
| ARG 8 | NTc.Cm35 | LYS 26 | 1.24x24 | VdWContact |
| ARG 8 | NTc.Cm35 | SER 262 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm35 | GLN 265 | 6.61x61 | HBDonor |
| ARG 8 | NTc.Cm35 | GLN 265 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm35 | ARG 275 | 7.27x26 | HBDonor |
| ARG 8 | NTc.Cm35 | ARG 275 | 7.27x26 | VdWContact |
| ARG 8 | NTc.Cm35 | SER 276 | 7.28x27 | HBDonor |
| ARG 8 | NTc.Cm35 | SER 276 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm35 | LEU 279 | 7.31x30 | VdWContact |
| ARG 8 | NTc.Cm35 | ASP 280 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm35 | ASP 280 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm35 | ASP 280 | 7.32x31 | VdWContact |
| GLN 10 | NTc.Cm33 | LEU 23 | - | Hydrophobic |
| GLN 10 | NTc.Cm33 | LEU 23 | - | VdWContact |
| GLN 10 | NTc.Cm33 | CYS 24 | - | HBAcceptor |
| GLN 10 | NTc.Cm33 | CYS 24 | - | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 24 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | ASN 271 | - | HBAcceptor |
| LEU 12 | NTc.Cm31 | ASN 271 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | ASN 271 | - | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 273 | 7.25x24 | Hydrophobic |
| LEU 12 | NTc.Cm31 | CYS 273 | 7.25x24 | VdWContact |
| GLN 13 | NTc.Cm30 | VAL 20 | - | VdWContact |
| GLN 13 | NTc.Cm30 | GLY 21 | - | VdWContact |
| LEU 15 | NTc.Cm28 | VAL 20 | - | VdWContact |
| ASN 22 | NTc.Cm21 | TYR 16 | - | Hydrophobic |
| ASN 22 | NTc.Cm21 | TYR 16 | - | VdWContact |
| ASN 27 | NTc.Cm16 | LEU 177 | - | Hydrophobic |
| ASN 27 | NTc.Cm16 | PHE 178 | - | VdWContact |
| ARG 29 | NTc.Cm14 | GLU 175 | - | VdWContact |
| ARG 29 | NTc.Cm14 | LEU 177 | - | Hydrophobic |
| SER 30 | NTc.Cm13 | GLU 175 | - | HBDonor |
| SER 30 | NTc.Cm13 | GLU 175 | - | VdWContact |
| SER 30 | NTc.Cm13 | LEU 186 | - | VdWContact |
| PRO 31 | NTc.Cm12 | TYR 187 | - | HBAcceptor |
| PRO 31 | NTc.Cm12 | TYR 187 | - | VdWContact |
| PRO 31 | NTc.Cm12 | GLU 189 | - | Hydrophobic |
| PRO 31 | NTc.Cm12 | VAL 192 | 5.31x32 | Hydrophobic |
| PRO 31 | NTc.Cm12 | VAL 192 | 5.31x32 | VdWContact |
| GLY 32 | NTc.Cm11 | ALA 185 | 45.52x52 | VdWContact |
| PRO 33 | NTc.Cm10 | ALA 185 | 45.52x52 | Hydrophobic |
| PRO 33 | NTc.Cm10 | ALA 185 | 45.52x52 | VdWContact |
| PRO 33 | NTc.Cm10 | TYR 187 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | ARG 196 | 5.35x36 | HBAcceptor |
| PRO 33 | NTc.Cm10 | ARG 196 | 5.35x36 | VdWContact |
| ALA 36 | NTc.Cm7 | VAL 192 | 5.31x32 | Hydrophobic |
| ALA 36 | NTc.Cm7 | VAL 192 | 5.31x32 | VdWContact |
| ALA 36 | NTc.Cm7 | TYR 193 | 5.32x33 | Hydrophobic |
| ALA 36 | NTc.Cm7 | ARG 196 | 5.35x36 | VdWContact |
| THR 38 | NTc.Cm5 | GLU 189 | - | HBDonor |
| THR 38 | NTc.Cm5 | GLU 189 | - | VdWContact |
| ILE 41 | NTc.Cm2 | LEU 23 | - | Hydrophobic |
| ILE 41 | NTc.Cm2 | LEU 177 | - | Hydrophobic |
| ILE 41 | NTc.Cm2 | PHE 178 | - | Hydrophobic |
| ILE 41 | NTc.Cm2 | PHE 178 | - | VdWContact |
| LEU 44 | CX.4 | TYR 16 | - | Hydrophobic |
| LYS 48 | cxb1.5 | LEU 22 | - | Hydrophobic |
| LYS 49 | cxb1.6 | LEU 23 | - | HBAcceptor |
| LYS 49 | cxb1.6 | LEU 23 | - | Hydrophobic |
| LYS 49 | cxb1.6 | LEU 23 | - | VdWContact |
| LYS 49 | cxb1.6 | PHE 178 | - | CationPi |
| LYS 49 | cxb1.6 | PHE 178 | - | Hydrophobic |
| LYS 49 | cxb1.6 | PHE 178 | - | VdWContact |
| CYS 51 | cxb1.10 | GLY 21 | - | HBDonor |
| CYS 51 | cxb1.10 | GLY 21 | - | VdWContact |
| MET 58 | B1.3 | PHE 11 | - | Hydrophobic |
