Predicted complex interactions
CXCL5_HUMAN + CCR3
SUMMARY
- Chemokine
- CXCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR3 View partner entry
- Partner description
- UniProt: P51677; Gene: ccr3_human; Family: Chemokine
- Interactions detected
- 114
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm48 | TYR 172 | 4.64x65 | HBDonor |
| ALA 1 | NTc.Cm48 | TYR 172 | 4.64x65 | VdWContact |
| ALA 1 | NTc.Cm48 | HIS 199 | 5.38x39 | VdWContact |
| ALA 1 | NTc.Cm48 | TYR 255 | 6.51x51 | VdWContact |
| GLY 2 | NTc.Cm47 | TYR 113 | 3.32x32 | VdWContact |
| GLY 2 | NTc.Cm47 | GLU 287 | 7.39x38 | VdWContact |
| GLY 2 | NTc.Cm47 | TYR 291 | 7.43x42 | VdWContact |
| PRO 3 | NTc.Cm46 | TYR 41 | 1.39x39 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TRP 90 | 2.60x60 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TRP 90 | 2.60x60 | VdWContact |
| PRO 3 | NTc.Cm46 | TYR 113 | 3.32x32 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TYR 113 | 3.32x32 | VdWContact |
| PRO 3 | NTc.Cm46 | GLU 287 | 7.39x38 | VdWContact |
| PRO 3 | NTc.Cm46 | TYR 291 | 7.43x42 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TYR 291 | 7.43x42 | VdWContact |
| ALA 4 | NTc.Cm45 | TRP 90 | 2.60x60 | Hydrophobic |
| ALA 4 | NTc.Cm45 | TYR 93 | 2.63x63 | Hydrophobic |
| ALA 4 | NTc.Cm45 | TYR 93 | 2.63x63 | VdWContact |
| ALA 4 | NTc.Cm45 | VAL 94 | 2.64x64 | Hydrophobic |
| ALA 4 | NTc.Cm45 | VAL 94 | 2.64x64 | VdWContact |
| ALA 6 | NTc.Cm43 | MET 33 | 1.31x31 | Hydrophobic |
| ALA 6 | NTc.Cm43 | MET 33 | 1.31x31 | VdWContact |
| ALA 6 | NTc.Cm43 | LEU 284 | 7.36x35 | Hydrophobic |
| VAL 7 | NTc.Cm42 | MET 33 | 1.31x31 | Hydrophobic |
| VAL 7 | NTc.Cm42 | VAL 94 | 2.64x64 | Hydrophobic |
| VAL 7 | NTc.Cm42 | VAL 94 | 2.64x64 | VdWContact |
| VAL 7 | NTc.Cm42 | HIS 97 | 2.67x67 | Hydrophobic |
| VAL 7 | NTc.Cm42 | HIS 97 | 2.67x67 | VdWContact |
| LEU 8 | NTc.Cm41 | ARG 30 | 1.28x28 | HBAcceptor |
| LEU 8 | NTc.Cm41 | ARG 30 | 1.28x28 | Hydrophobic |
| LEU 8 | NTc.Cm41 | ARG 30 | 1.28x28 | VdWContact |
| LEU 8 | NTc.Cm41 | HIS 97 | 2.67x67 | Hydrophobic |
| LEU 8 | NTc.Cm41 | HIS 97 | 2.67x67 | VdWContact |
| LEU 8 | NTc.Cm41 | GLU 180 | - | VdWContact |
| LEU 8 | NTc.Cm41 | LEU 182 | - | Hydrophobic |
| ARG 9 | NTc.Cm40 | ARG 30 | 1.28x28 | HBAcceptor |
| ARG 9 | NTc.Cm40 | ARG 30 | 1.28x28 | VdWContact |
| ARG 9 | NTc.Cm40 | LEU 177 | - | Hydrophobic |
| ARG 9 | NTc.Cm40 | LEU 177 | - | VdWContact |
| ARG 9 | NTc.Cm40 | PHE 178 | - | VdWContact |
| ARG 9 | NTc.Cm40 | GLU 180 | - | Cationic |
| GLU 10 | NTc.Cm39 | LEU 177 | - | Hydrophobic |
| GLU 10 | NTc.Cm39 | LEU 177 | - | VdWContact |
| GLU 10 | NTc.Cm39 | LEU 182 | - | Hydrophobic |
| GLU 10 | NTc.Cm39 | LEU 182 | - | VdWContact |
| ARG 12 | NTc.Cm37 | LYS 26 | 1.24x24 | VdWContact |
| ARG 12 | NTc.Cm37 | GLN 265 | 6.61x61 | HBDonor |
| ARG 12 | NTc.Cm37 | GLN 265 | 6.61x61 | VdWContact |
| ARG 12 | NTc.Cm37 | SER 276 | 7.28x27 | VdWContact |
| ARG 12 | NTc.Cm37 | LEU 279 | 7.31x30 | VdWContact |
| ARG 12 | NTc.Cm37 | ASP 280 | 7.32x31 | Cationic |
| ARG 12 | NTc.Cm37 | ASP 280 | 7.32x31 | HBDonor |
| ARG 12 | NTc.Cm37 | ASP 280 | 7.32x31 | VdWContact |
| VAL 14 | NTc.Cm35 | LEU 23 | - | Hydrophobic |
| VAL 14 | NTc.Cm35 | LEU 23 | - | VdWContact |
| VAL 14 | NTc.Cm35 | CYS 24 | - | HBAcceptor |
| VAL 14 | NTc.Cm35 | CYS 24 | - | VdWContact |
| LEU 16 | NTc.Cm33 | CYS 24 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | ASN 271 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | ASN 271 | - | VdWContact |
| LEU 16 | NTc.Cm33 | ASP 272 | 7.24x23 | VdWContact |
| LEU 16 | NTc.Cm33 | CYS 273 | 7.25x24 | Hydrophobic |
| LEU 16 | NTc.Cm33 | CYS 273 | 7.25x24 | VdWContact |
| THR 19 | NTc.Cm30 | VAL 20 | - | Hydrophobic |
| THR 19 | NTc.Cm30 | GLY 21 | - | HBAcceptor |
| THR 19 | NTc.Cm30 | GLY 21 | - | VdWContact |
| GLY 21 | NTc.Cm28 | TYR 16 | - | VdWContact |
| HIS 23 | NTc.Cm26 | THR 10 | - | Hydrophobic |
| HIS 23 | NTc.Cm26 | PHE 11 | - | VdWContact |
| PRO 24 | NTc.Cm25 | VAL 8 | - | Hydrophobic |
| PRO 24 | NTc.Cm25 | VAL 8 | - | VdWContact |
| PRO 24 | NTc.Cm25 | PHE 11 | - | Hydrophobic |
| ILE 27 | NTc.Cm22 | LEU 5 | - | Hydrophobic |
| GLN 31 | NTc.Cm18 | PHE 178 | - | HBAcceptor |
| GLN 31 | NTc.Cm18 | PHE 178 | - | HBDonor |
| GLN 31 | NTc.Cm18 | PHE 178 | - | Hydrophobic |
| GLN 31 | NTc.Cm18 | PHE 178 | - | VdWContact |
| PHE 33 | NTc.Cm16 | GLU 175 | - | VdWContact |
| PHE 33 | NTc.Cm16 | LEU 177 | - | Hydrophobic |
| PHE 33 | NTc.Cm16 | LEU 177 | - | VdWContact |
| PHE 33 | NTc.Cm16 | PHE 178 | - | Hydrophobic |
| ALA 34 | NTc.Cm15 | LEU 186 | - | Hydrophobic |
| ILE 35 | NTc.Cm14 | GLU 189 | - | Hydrophobic |
| ILE 35 | NTc.Cm14 | GLU 189 | - | VdWContact |
| ILE 35 | NTc.Cm14 | VAL 192 | 5.31x32 | Hydrophobic |
| ILE 35 | NTc.Cm14 | VAL 192 | 5.31x32 | VdWContact |
| GLY 36 | NTc.Cm13 | VAL 192 | 5.31x32 | VdWContact |
| PRO 37 | NTc.Cm12 | ALA 185 | 45.52x52 | Hydrophobic |
| PRO 37 | NTc.Cm12 | ALA 185 | 45.52x52 | VdWContact |
| PRO 37 | NTc.Cm12 | TYR 187 | - | Hydrophobic |
| PRO 37 | NTc.Cm12 | TYR 187 | - | VdWContact |
| PRO 37 | NTc.Cm12 | ARG 196 | 5.35x36 | VdWContact |
| GLN 38 | NTc.Cm11 | ARG 196 | 5.35x36 | HBAcceptor |
| GLN 38 | NTc.Cm11 | ARG 196 | 5.35x36 | VdWContact |
| SER 40 | NTc.Cm9 | TYR 193 | 5.32x33 | HBDonor |
| SER 40 | NTc.Cm9 | TYR 193 | 5.32x33 | VdWContact |
| VAL 45 | NTc.Cm4 | LEU 23 | - | Hydrophobic |
| VAL 45 | NTc.Cm4 | LEU 23 | - | VdWContact |
| VAL 45 | NTc.Cm4 | PHE 178 | - | Hydrophobic |
| VAL 45 | NTc.Cm4 | PHE 178 | - | VdWContact |
| SER 47 | NTc.Cm2 | PHE 178 | - | VdWContact |
| GLU 53 | cxb1.2 | LEU 23 | - | Hydrophobic |
| GLU 53 | cxb1.2 | LEU 23 | - | VdWContact |
| ILE 54 | cxb1.5 | VAL 20 | - | Hydrophobic |
| ILE 54 | cxb1.5 | LEU 22 | - | Hydrophobic |
| ILE 54 | cxb1.5 | LEU 23 | - | VdWContact |
| CYS 55 | cxb1.6 | GLY 21 | - | HBDonor |
| CYS 55 | cxb1.6 | GLY 21 | - | VdWContact |
| CYS 55 | cxb1.6 | LEU 23 | - | Hydrophobic |
| CYS 55 | cxb1.6 | LEU 23 | - | VdWContact |
| PHE 62 | B1.1 | PHE 11 | - | Hydrophobic |
| VAL 66 | B1.5 | LEU 5 | - | Hydrophobic |
| GLU 77 | b1b2.14 | MET 1 | - | Hydrophobic |
| GLU 77 | b1b2.14 | MET 1 | - | VdWContact |
