Predicted complex interactions
CXCL8_HUMAN + CCR3
SUMMARY
- Chemokine
- CXCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR3 View partner entry
- Partner description
- UniProt: P51677; Gene: ccr3_human; Family: Chemokine
- Interactions detected
- 56
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| TYR 20 | NTc.Cm14 | PHE 11 | - | Hydrophobic |
| TYR 20 | NTc.Cm14 | PHE 11 | - | VdWContact |
| TYR 20 | NTc.Cm14 | LEU 23 | - | Hydrophobic |
| TYR 20 | NTc.Cm14 | LEU 23 | - | VdWContact |
| LYS 22 | NTc.Cm12 | GLU 9 | - | Cationic |
| LYS 22 | NTc.Cm12 | GLU 9 | - | Hydrophobic |
| LYS 22 | NTc.Cm12 | GLU 9 | - | VdWContact |
| LYS 22 | NTc.Cm12 | PHE 11 | - | Hydrophobic |
| LYS 22 | NTc.Cm12 | PHE 11 | - | VdWContact |
| LYS 22 | NTc.Cm12 | GLU 25 | - | Cationic |
| LYS 22 | NTc.Cm12 | GLU 25 | - | HBDonor |
| LYS 22 | NTc.Cm12 | GLU 25 | - | VdWContact |
| PRO 23 | NTc.Cm11 | PHE 11 | - | HBAcceptor |
| PRO 23 | NTc.Cm11 | PHE 11 | - | VdWContact |
| PRO 23 | NTc.Cm11 | PHE 178 | - | Hydrophobic |
| PRO 23 | NTc.Cm11 | PHE 178 | - | VdWContact |
| PHE 24 | NTc.Cm10 | PHE 11 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | LEU 23 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | LEU 23 | - | VdWContact |
| HIS 25 | NTc.Cm9 | THR 13 | - | Hydrophobic |
| HIS 25 | NTc.Cm9 | GLU 175 | - | VdWContact |
| HIS 25 | NTc.Cm9 | LEU 177 | - | Hydrophobic |
| HIS 25 | NTc.Cm9 | LEU 177 | - | VdWContact |
| LYS 27 | NTc.Cm7 | ASP 18 | - | Cationic |
| LYS 27 | NTc.Cm7 | ASP 18 | - | HBDonor |
| LYS 27 | NTc.Cm7 | ASP 18 | - | VdWContact |
| PHE 28 | NTc.Cm6 | THR 13 | - | Hydrophobic |
| PHE 28 | NTc.Cm6 | ASP 18 | - | Hydrophobic |
| PHE 28 | NTc.Cm6 | ASP 19 | - | VdWContact |
| PHE 28 | NTc.Cm6 | LEU 23 | - | Hydrophobic |
| PHE 28 | NTc.Cm6 | LEU 23 | - | VdWContact |
| LEU 50 | B1.3 | LEU 23 | - | Hydrophobic |
| LEU 50 | B1.3 | LEU 23 | - | VdWContact |
| SER 51 | B1.4 | GLY 21 | - | VdWContact |
| ASP 52 | B1.5 | GLY 21 | - | HBDonor |
| ASP 52 | B1.5 | GLY 21 | - | VdWContact |
| ASP 52 | B1.5 | LEU 22 | - | Hydrophobic |
| ASP 52 | B1.5 | LEU 22 | - | VdWContact |
| ASP 52 | B1.5 | LEU 23 | - | HBAcceptor |
| ASP 52 | B1.5 | LEU 23 | - | VdWContact |
| ARG 54 | B1.7 | LEU 23 | - | HBDonor |
| ARG 54 | B1.7 | LEU 23 | - | VdWContact |
| LEU 56 | b1b2.6 | LEU 23 | - | Hydrophobic |
| LEU 56 | b1b2.6 | LEU 23 | - | VdWContact |
| TRP 64 | b1b2.16 | PHE 178 | - | Hydrophobic |
| TRP 64 | b1b2.16 | PHE 178 | - | VdWContact |
| ARG 67 | B2.3 | PHE 178 | - | Hydrophobic |
| ARG 67 | B2.3 | PHE 178 | - | VdWContact |
| VAL 68 | B2.4 | PHE 178 | - | Hydrophobic |
| VAL 68 | B2.4 | PHE 178 | - | VdWContact |
| LYS 71 | b2b3.2 | GLU 175 | - | Cationic |
| LYS 71 | b2b3.2 | GLU 176 | - | HBDonor |
| LYS 71 | b2b3.2 | GLU 176 | - | VdWContact |
| ARG 75 | B3.1 | GLU 189 | - | Cationic |
| ARG 75 | B3.1 | GLU 189 | - | HBDonor |
| ARG 75 | B3.1 | GLU 189 | - | VdWContact |
