Predicted complex interactions
CCL15_HUMAN + CCR4
SUMMARY
- Chemokine
- CCL15_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR4 View partner entry
- Partner description
- UniProt: P51679; Gene: ccr4_human; Family: Chemokine
- Interactions detected
- 115
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLU 18 | NTc.Cm35 | SER 192 | - | VdWContact |
| GLU 18 | NTc.Cm35 | LEU 193 | - | Hydrophobic |
| GLU 18 | NTc.Cm35 | LEU 193 | - | VdWContact |
| GLU 18 | NTc.Cm35 | ASN 194 | 5.30x31 | HBAcceptor |
| GLU 18 | NTc.Cm35 | ASN 194 | 5.30x31 | VdWContact |
| GLU 18 | NTc.Cm35 | SER 195 | 5.31x32 | HBAcceptor |
| GLU 18 | NTc.Cm35 | SER 195 | 5.31x32 | VdWContact |
| ASN 19 | NTc.Cm34 | SER 195 | 5.31x32 | VdWContact |
| PRO 20 | NTc.Cm33 | LYS 190 | - | Hydrophobic |
| PRO 20 | NTc.Cm33 | LYS 190 | - | VdWContact |
| PRO 20 | NTc.Cm33 | TYR 191 | - | VdWContact |
| VAL 21 | NTc.Cm32 | THR 189 | 45.52x52 | VdWContact |
| VAL 21 | NTc.Cm32 | TYR 191 | - | HBAcceptor |
| VAL 21 | NTc.Cm32 | TYR 191 | - | Hydrophobic |
| VAL 21 | NTc.Cm32 | TYR 191 | - | VdWContact |
| VAL 21 | NTc.Cm32 | SER 195 | 5.31x32 | VdWContact |
| VAL 21 | NTc.Cm32 | TRP 198 | 5.34x35 | Hydrophobic |
| VAL 21 | NTc.Cm32 | LYS 199 | 5.35x36 | Hydrophobic |
| VAL 21 | NTc.Cm32 | LYS 199 | 5.35x36 | VdWContact |
| VAL 22 | NTc.Cm31 | TYR 179 | - | Hydrophobic |
| VAL 22 | NTc.Cm31 | LYS 188 | 45.51x51 | Hydrophobic |
| VAL 22 | NTc.Cm31 | LYS 188 | 45.51x51 | VdWContact |
| VAL 22 | NTc.Cm31 | THR 189 | 45.52x52 | VdWContact |
| LEU 23 | NTc.Cm30 | LEU 118 | 3.33x33 | Hydrophobic |
| LEU 23 | NTc.Cm30 | THR 189 | 45.52x52 | Hydrophobic |
| LEU 23 | NTc.Cm30 | THR 189 | 45.52x52 | VdWContact |
| ASN 24 | NTc.Cm29 | GLU 265 | 6.58x58 | HBDonor |
| ASN 24 | NTc.Cm29 | GLU 265 | 6.58x58 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 46 | 1.39x39 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 46 | 1.39x39 | VdWContact |
| PHE 26 | NTc.Cm27 | TRP 95 | 2.60x60 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TRP 95 | 2.60x60 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 98 | 2.63x63 | Hydrophobic |
| PHE 26 | NTc.Cm27 | LYS 188 | 45.51x51 | VdWContact |
| HIS 27 | NTc.Cm26 | GLU 265 | 6.58x58 | VdWContact |
| HIS 27 | NTc.Cm26 | ILE 286 | 7.35x34 | Hydrophobic |
| HIS 27 | NTc.Cm26 | ILE 286 | 7.35x34 | VdWContact |
| PHE 28 | NTc.Cm25 | LYS 35 | 1.28x28 | Hydrophobic |
| PHE 28 | NTc.Cm25 | LYS 35 | 1.28x28 | VdWContact |
| PHE 28 | NTc.Cm25 | HIS 184 | - | Hydrophobic |
| PHE 28 | NTc.Cm25 | TYR 186 | - | Hydrophobic |
| PHE 28 | NTc.Cm25 | TYR 186 | - | PiStacking |
| PHE 28 | NTc.Cm25 | TYR 186 | - | VdWContact |
| ALA 29 | NTc.Cm24 | LYS 31 | 1.24x24 | Hydrophobic |
| ALA 29 | NTc.Cm24 | LYS 31 | 1.24x24 | VdWContact |
| ALA 29 | NTc.Cm24 | ILE 34 | 1.27x27 | Hydrophobic |
| ALA 29 | NTc.Cm24 | ASP 283 | 7.32x31 | Hydrophobic |
| ALA 30 | NTc.Cm23 | LYS 31 | 1.24x24 | VdWContact |
| ASP 31 | NTc.Cm22 | CYS 29 | - | VdWContact |
| ASP 31 | NTc.Cm22 | THR 30 | - | VdWContact |
| ASP 31 | NTc.Cm22 | LYS 31 | 1.24x24 | HBAcceptor |
| ASP 31 | NTc.Cm22 | LYS 31 | 1.24x24 | VdWContact |
| CYS 32 | NTc.Cm21 | CYS 29 | - | HBAcceptor |
| CYS 32 | NTc.Cm21 | CYS 29 | - | HBDonor |
| CYS 32 | NTc.Cm21 | CYS 29 | - | VdWContact |
| THR 34 | NTc.Cm19 | CYS 29 | - | Hydrophobic |
| THR 34 | NTc.Cm19 | CYS 276 | 7.25x24 | Hydrophobic |
| THR 34 | NTc.Cm19 | GLU 279 | 7.28x27 | VdWContact |
| TYR 36 | NTc.Cm17 | PRO 26 | - | VdWContact |
| ILE 37 | NTc.Cm16 | TYR 19 | - | Hydrophobic |
| ILE 37 | NTc.Cm16 | TYR 19 | - | VdWContact |
| ILE 37 | NTc.Cm16 | PRO 26 | - | Hydrophobic |
| ILE 37 | NTc.Cm16 | PRO 26 | - | VdWContact |
| SER 38 | NTc.Cm15 | GLU 23 | - | HBDonor |
| SER 38 | NTc.Cm15 | GLU 23 | - | VdWContact |
| GLN 39 | NTc.Cm14 | TYR 22 | - | VdWContact |
| PRO 42 | NTc.Cm11 | ILE 15 | - | Hydrophobic |
| PRO 42 | NTc.Cm11 | TYR 19 | - | Hydrophobic |
| PRO 42 | NTc.Cm11 | TYR 19 | - | VdWContact |
| LEU 45 | NTc.Cm8 | ASP 12 | - | VdWContact |
| LEU 45 | NTc.Cm8 | ILE 15 | - | Hydrophobic |
| LEU 45 | NTc.Cm8 | ILE 15 | - | VdWContact |
| LEU 45 | NTc.Cm8 | TYR 16 | - | HBAcceptor |
| LEU 45 | NTc.Cm8 | TYR 16 | - | Hydrophobic |
| LEU 45 | NTc.Cm8 | TYR 16 | - | VdWContact |
| LEU 45 | NTc.Cm8 | TYR 19 | - | Hydrophobic |
| MET 46 | NTc.Cm7 | TYR 19 | - | Hydrophobic |
| PHE 50 | NTc.Cm3 | ARG 182 | - | VdWContact |
| GLU 51 | NTc.Cm2 | ARG 182 | - | HBAcceptor |
| GLU 51 | NTc.Cm2 | ARG 182 | - | VdWContact |
| SER 53 | CX.1 | GLU 181 | - | HBDonor |
| SER 53 | CX.1 | GLU 181 | - | VdWContact |
| SER 53 | CX.1 | ARG 182 | - | HBAcceptor |
| GLU 55 | cxb1.1 | LYS 188 | 45.51x51 | Anionic |
| GLU 55 | cxb1.1 | LYS 188 | 45.51x51 | HBAcceptor |
| GLU 55 | cxb1.1 | LYS 188 | 45.51x51 | VdWContact |
| LYS 58 | cxb1.6 | GLU 271 | 6.64x64 | Cationic |
| LYS 58 | cxb1.6 | GLU 271 | 6.64x64 | HBDonor |
| LYS 58 | cxb1.6 | GLU 271 | 6.64x64 | VdWContact |
| LYS 58 | cxb1.6 | GLN 274 | - | HBDonor |
| LYS 58 | cxb1.6 | GLN 274 | - | VdWContact |
| ILE 62 | cxb1.11 | PRO 28 | - | Hydrophobic |
| ILE 62 | cxb1.11 | PRO 28 | - | VdWContact |
| THR 65 | cxb1.16 | TYR 20 | - | Hydrophobic |
| THR 65 | cxb1.16 | TYR 20 | - | VdWContact |
| LYS 66 | B1.1 | ASP 12 | - | Cationic |
| LYS 66 | B1.1 | ASP 12 | - | HBDonor |
| LYS 66 | B1.1 | ASP 12 | - | VdWContact |
| LYS 66 | B1.1 | TYR 16 | - | Hydrophobic |
| LYS 66 | B1.1 | TYR 16 | - | VdWContact |
| LYS 67 | B1.2 | GLU 13 | - | Cationic |
| LYS 67 | B1.2 | TYR 16 | - | HBDonor |
| LYS 67 | B1.2 | TYR 16 | - | Hydrophobic |
| LYS 67 | B1.2 | TYR 16 | - | VdWContact |
| ARG 69 | B1.4 | TYR 20 | - | Hydrophobic |
| ARG 69 | B1.4 | TYR 20 | - | VdWContact |
| GLN 70 | B1.5 | PRO 28 | - | Hydrophobic |
| GLN 70 | B1.5 | PRO 28 | - | VdWContact |
| VAL 71 | B1.6 | ILE 25 | - | Hydrophobic |
| VAL 71 | B1.6 | ILE 25 | - | VdWContact |
| CYS 72 | B1.7 | PRO 26 | - | HBDonor |
| CYS 72 | B1.7 | PRO 26 | - | Hydrophobic |
| CYS 72 | B1.7 | PRO 26 | - | VdWContact |
| CYS 72 | B1.7 | PRO 28 | - | VdWContact |
| ILE 92 | B3.2 | ARG 182 | - | VdWContact |
