Predicted complex interactions
CCL16_HUMAN + CCR4
SUMMARY
- Chemokine
- CCL16_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR4 View partner entry
- Partner description
- UniProt: P51679; Gene: ccr4_human; Family: Chemokine
- Interactions detected
- 128
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm36 | THR 189 | 45.52x52 | VdWContact |
| GLN 1 | NTc.Cm36 | TYR 191 | - | VdWContact |
| GLN 1 | NTc.Cm36 | LYS 199 | 5.35x36 | VdWContact |
| PRO 2 | NTc.Cm35 | THR 189 | 45.52x52 | Hydrophobic |
| PRO 2 | NTc.Cm35 | THR 189 | 45.52x52 | VdWContact |
| PRO 2 | NTc.Cm35 | TYR 191 | - | Hydrophobic |
| PRO 2 | NTc.Cm35 | TYR 191 | - | VdWContact |
| LYS 3 | NTc.Cm34 | LEU 262 | 6.55x55 | Hydrophobic |
| LYS 3 | NTc.Cm34 | GLU 265 | 6.58x58 | Cationic |
| LYS 3 | NTc.Cm34 | GLU 265 | 6.58x58 | HBDonor |
| LYS 3 | NTc.Cm34 | GLU 265 | 6.58x58 | VdWContact |
| VAL 4 | NTc.Cm33 | TRP 95 | 2.60x60 | Hydrophobic |
| VAL 4 | NTc.Cm33 | TRP 95 | 2.60x60 | VdWContact |
| VAL 4 | NTc.Cm33 | SER 114 | 3.29x29 | VdWContact |
| VAL 4 | NTc.Cm33 | THR 189 | 45.52x52 | VdWContact |
| PRO 5 | NTc.Cm32 | TRP 95 | 2.60x60 | Hydrophobic |
| PRO 5 | NTc.Cm32 | TYR 117 | 3.32x32 | Hydrophobic |
| PRO 5 | NTc.Cm32 | TYR 117 | 3.32x32 | VdWContact |
| GLU 6 | NTc.Cm31 | LYS 188 | 45.51x51 | Hydrophobic |
| TRP 7 | NTc.Cm30 | GLU 265 | 6.58x58 | Hydrophobic |
| TRP 7 | NTc.Cm30 | GLU 265 | 6.58x58 | VdWContact |
| TRP 7 | NTc.Cm30 | ASP 283 | 7.32x31 | VdWContact |
| TRP 7 | NTc.Cm30 | ILE 286 | 7.35x34 | Hydrophobic |
| TRP 7 | NTc.Cm30 | ILE 286 | 7.35x34 | VdWContact |
| TRP 7 | NTc.Cm30 | GLN 287 | 7.36x35 | HBAcceptor |
| TRP 7 | NTc.Cm30 | GLN 287 | 7.36x35 | Hydrophobic |
| TRP 7 | NTc.Cm30 | GLN 287 | 7.36x35 | VdWContact |
| TRP 7 | NTc.Cm30 | GLU 290 | 7.39x38 | VdWContact |
| VAL 8 | NTc.Cm29 | LEU 42 | 1.35x35 | Hydrophobic |
| VAL 8 | NTc.Cm29 | TYR 46 | 1.39x39 | Hydrophobic |
| VAL 8 | NTc.Cm29 | TRP 95 | 2.60x60 | VdWContact |
| VAL 8 | NTc.Cm29 | TYR 98 | 2.63x63 | Hydrophobic |
| VAL 8 | NTc.Cm29 | ALA 99 | 2.64x64 | Hydrophobic |
| VAL 8 | NTc.Cm29 | ALA 99 | 2.64x64 | VdWContact |
| ASN 9 | NTc.Cm28 | LYS 35 | 1.28x28 | HBAcceptor |
| ASN 9 | NTc.Cm28 | LYS 35 | 1.28x28 | VdWContact |
| ASN 9 | NTc.Cm28 | TYR 98 | 2.63x63 | HBDonor |
| ASN 9 | NTc.Cm28 | TYR 98 | 2.63x63 | Hydrophobic |
| ASN 9 | NTc.Cm28 | TYR 98 | 2.63x63 | VdWContact |
| ASN 9 | NTc.Cm28 | ASP 101 | 2.66x66 | VdWContact |
| ASN 9 | NTc.Cm28 | HIS 184 | - | VdWContact |
| ASN 9 | NTc.Cm28 | TYR 186 | - | Hydrophobic |
| ASN 9 | NTc.Cm28 | TYR 186 | - | VdWContact |
| ASN 9 | NTc.Cm28 | LYS 188 | 45.51x51 | HBAcceptor |
| ASN 9 | NTc.Cm28 | LYS 188 | 45.51x51 | VdWContact |
| THR 10 | NTc.Cm27 | LYS 35 | 1.28x28 | VdWContact |
| PRO 11 | NTc.Cm26 | LYS 31 | 1.24x24 | VdWContact |
| SER 12 | NTc.Cm25 | LYS 31 | 1.24x24 | HBAcceptor |
| SER 12 | NTc.Cm25 | LYS 31 | 1.24x24 | VdWContact |
| SER 12 | NTc.Cm25 | GLU 32 | 1.25x25 | VdWContact |
| THR 13 | NTc.Cm24 | PRO 28 | - | Hydrophobic |
| THR 13 | NTc.Cm24 | PRO 28 | - | VdWContact |
| THR 13 | NTc.Cm24 | CYS 29 | - | VdWContact |
| CYS 14 | NTc.Cm23 | CYS 29 | - | HBAcceptor |
| CYS 14 | NTc.Cm23 | CYS 29 | - | HBDonor |
| CYS 14 | NTc.Cm23 | CYS 29 | - | VdWContact |
| LEU 16 | NTc.Cm21 | CYS 29 | - | Hydrophobic |
| LEU 16 | NTc.Cm21 | CYS 276 | 7.25x24 | Hydrophobic |
| LEU 16 | NTc.Cm21 | GLU 279 | 7.28x27 | VdWContact |
| LYS 17 | NTc.Cm20 | PRO 26 | - | Hydrophobic |
| LYS 17 | NTc.Cm20 | PRO 26 | - | VdWContact |
| TYR 18 | NTc.Cm19 | PRO 26 | - | VdWContact |
| TYR 19 | NTc.Cm18 | TYR 19 | - | Hydrophobic |
| TYR 19 | NTc.Cm18 | TYR 19 | - | VdWContact |
| TYR 19 | NTc.Cm18 | GLU 23 | - | HBDonor |
| TYR 19 | NTc.Cm18 | GLU 23 | - | Hydrophobic |
| TYR 19 | NTc.Cm18 | GLU 23 | - | VdWContact |
| TYR 19 | NTc.Cm18 | ILE 25 | - | Hydrophobic |
| TYR 19 | NTc.Cm18 | ILE 25 | - | VdWContact |
| TYR 19 | NTc.Cm18 | PRO 26 | - | Hydrophobic |
| TYR 19 | NTc.Cm18 | PRO 26 | - | VdWContact |
| LYS 21 | NTc.Cm16 | GLU 23 | - | Cationic |
| LYS 21 | NTc.Cm16 | GLU 23 | - | HBDonor |
| LYS 21 | NTc.Cm16 | GLU 23 | - | VdWContact |
| LEU 23 | NTc.Cm14 | TYR 19 | - | Hydrophobic |
| LEU 23 | NTc.Cm14 | TYR 19 | - | VdWContact |
| PRO 24 | NTc.Cm13 | ILE 15 | - | Hydrophobic |
| PRO 24 | NTc.Cm13 | TYR 19 | - | Hydrophobic |
| PRO 24 | NTc.Cm13 | TYR 19 | - | VdWContact |
| ARG 26 | NTc.Cm11 | ASP 8 | - | Cationic |
| LEU 27 | NTc.Cm10 | ILE 15 | - | Hydrophobic |
| LEU 27 | NTc.Cm10 | ILE 15 | - | VdWContact |
| LEU 27 | NTc.Cm10 | TYR 16 | - | Hydrophobic |
| LEU 27 | NTc.Cm10 | TYR 16 | - | VdWContact |
| LEU 27 | NTc.Cm10 | TYR 19 | - | Hydrophobic |
| LEU 27 | NTc.Cm10 | TYR 20 | - | Hydrophobic |
| LEU 27 | NTc.Cm10 | TYR 20 | - | VdWContact |
| LYS 33 | NTc.Cm4 | ARG 182 | - | VdWContact |
| ASN 36 | NTc.Cm1 | TYR 179 | - | Hydrophobic |
| ASN 36 | NTc.Cm1 | TYR 179 | - | VdWContact |
| ASN 36 | NTc.Cm1 | GLU 181 | - | HBDonor |
| ASN 36 | NTc.Cm1 | GLU 181 | - | VdWContact |
| HIS 38 | CX.5 | LYS 199 | 5.35x36 | VdWContact |
| HIS 38 | CX.5 | GLU 269 | 6.62x62 | HBDonor |
| HIS 38 | CX.5 | GLU 269 | 6.62x62 | Hydrophobic |
| HIS 38 | CX.5 | GLU 269 | 6.62x62 | VdWContact |
| ILE 43 | cxb1.7 | PRO 28 | - | Hydrophobic |
| THR 46 | cxb1.11 | TYR 16 | - | HBAcceptor |
| THR 46 | cxb1.11 | TYR 16 | - | VdWContact |
| THR 46 | cxb1.11 | TYR 20 | - | Hydrophobic |
| THR 46 | cxb1.11 | TYR 20 | - | VdWContact |
| LYS 47 | cxb1.14 | ASP 12 | - | Cationic |
| LYS 47 | cxb1.14 | ASP 12 | - | HBDonor |
| LYS 47 | cxb1.14 | ASP 12 | - | VdWContact |
| LYS 47 | cxb1.14 | TYR 16 | - | Hydrophobic |
| LYS 47 | cxb1.14 | TYR 16 | - | VdWContact |
| ARG 48 | cxb1.15 | GLU 13 | - | Cationic |
| ARG 48 | cxb1.15 | GLU 13 | - | VdWContact |
| ARG 48 | cxb1.15 | TYR 16 | - | CationPi |
| ARG 48 | cxb1.15 | TYR 16 | - | HBDonor |
| ARG 48 | cxb1.15 | TYR 16 | - | Hydrophobic |
| ARG 48 | cxb1.15 | TYR 16 | - | VdWContact |
| ARG 50 | B1.1 | TYR 20 | - | Hydrophobic |
| ARG 50 | B1.1 | TYR 20 | - | VdWContact |
| GLU 51 | B1.2 | PRO 28 | - | Hydrophobic |
| VAL 52 | B1.3 | ILE 25 | - | Hydrophobic |
| CYS 53 | B1.4 | PRO 26 | - | HBDonor |
| CYS 53 | B1.4 | PRO 26 | - | Hydrophobic |
| CYS 53 | B1.4 | PRO 26 | - | VdWContact |
| LEU 72 | b2b3.11 | ARG 182 | - | VdWContact |
| LEU 73 | b2b3.12 | ARG 182 | - | HBAcceptor |
| LEU 73 | b2b3.12 | ARG 182 | - | VdWContact |
| PRO 74 | B3.1 | ARG 182 | - | HBAcceptor |
| PRO 74 | B3.1 | ARG 182 | - | VdWContact |
| THR 75 | B3.2 | ARG 182 | - | VdWContact |
| ARG 76 | B3.3 | GLU 32 | 1.25x25 | Cationic |
| ARG 76 | B3.3 | GLU 32 | 1.25x25 | VdWContact |
| LEU 78 | b3h.1 | GLU 32 | 1.25x25 | Hydrophobic |
