Predicted complex interactions
CCL18_HUMAN + CCR4
SUMMARY
- Chemokine
- CCL18_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR4 View partner entry
- Partner description
- UniProt: P51679; Gene: ccr4_human; Family: Chemokine
- Interactions detected
- 108
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm29 | TRP 95 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm29 | TYR 117 | 3.32x32 | HBDonor |
| ALA 1 | NTc.Cm29 | TYR 117 | 3.32x32 | VdWContact |
| ALA 1 | NTc.Cm29 | GLU 290 | 7.39x38 | Cationic |
| ALA 1 | NTc.Cm29 | GLU 290 | 7.39x38 | HBDonor |
| ALA 1 | NTc.Cm29 | GLU 290 | 7.39x38 | VdWContact |
| GLN 2 | NTc.Cm28 | LYS 188 | 45.51x51 | HBAcceptor |
| GLN 2 | NTc.Cm28 | LYS 188 | 45.51x51 | VdWContact |
| GLN 2 | NTc.Cm28 | GLU 265 | 6.58x58 | HBDonor |
| GLN 2 | NTc.Cm28 | GLU 265 | 6.58x58 | VdWContact |
| GLN 2 | NTc.Cm28 | GLU 290 | 7.39x38 | HBDonor |
| GLN 2 | NTc.Cm28 | GLU 290 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm27 | LEU 42 | 1.35x35 | Hydrophobic |
| VAL 3 | NTc.Cm27 | TYR 46 | 1.39x39 | Hydrophobic |
| VAL 3 | NTc.Cm27 | TYR 98 | 2.63x63 | Hydrophobic |
| VAL 3 | NTc.Cm27 | ALA 99 | 2.64x64 | Hydrophobic |
| VAL 3 | NTc.Cm27 | ALA 99 | 2.64x64 | VdWContact |
| GLY 4 | NTc.Cm26 | LYS 188 | 45.51x51 | HBAcceptor |
| GLY 4 | NTc.Cm26 | LYS 188 | 45.51x51 | VdWContact |
| ASN 6 | NTc.Cm24 | LYS 35 | 1.28x28 | Hydrophobic |
| ASN 6 | NTc.Cm24 | LYS 35 | 1.28x28 | VdWContact |
| ASN 6 | NTc.Cm24 | TYR 186 | - | HBDonor |
| ASN 6 | NTc.Cm24 | TYR 186 | - | Hydrophobic |
| ASN 6 | NTc.Cm24 | TYR 186 | - | VdWContact |
| LYS 7 | NTc.Cm23 | LYS 31 | 1.24x24 | Hydrophobic |
| LYS 7 | NTc.Cm23 | LYS 31 | 1.24x24 | VdWContact |
| LYS 7 | NTc.Cm23 | GLU 279 | 7.28x27 | Cationic |
| LYS 7 | NTc.Cm23 | ASP 283 | 7.32x31 | Cationic |
| LYS 7 | NTc.Cm23 | ASP 283 | 7.32x31 | HBDonor |
| LYS 7 | NTc.Cm23 | ASP 283 | 7.32x31 | VdWContact |
| GLU 8 | NTc.Cm22 | LYS 31 | 1.24x24 | HBAcceptor |
| GLU 8 | NTc.Cm22 | LYS 31 | 1.24x24 | VdWContact |
| GLU 8 | NTc.Cm22 | ARG 182 | - | Anionic |
| GLU 8 | NTc.Cm22 | ARG 182 | - | HBAcceptor |
| GLU 8 | NTc.Cm22 | ARG 182 | - | VdWContact |
| LEU 9 | NTc.Cm21 | PRO 28 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 29 | - | VdWContact |
| LEU 9 | NTc.Cm21 | THR 30 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | THR 30 | - | VdWContact |
| CYS 10 | NTc.Cm20 | CYS 29 | - | HBAcceptor |
| CYS 10 | NTc.Cm20 | CYS 29 | - | HBDonor |
| CYS 10 | NTc.Cm20 | CYS 29 | - | VdWContact |
| LEU 12 | NTc.Cm18 | CYS 29 | - | Hydrophobic |
| LEU 12 | NTc.Cm18 | CYS 276 | 7.25x24 | Hydrophobic |
| LEU 12 | NTc.Cm18 | GLU 279 | 7.28x27 | VdWContact |
| VAL 13 | NTc.Cm17 | PRO 26 | - | Hydrophobic |
| VAL 13 | NTc.Cm17 | PRO 26 | - | VdWContact |
| TYR 14 | NTc.Cm16 | PRO 26 | - | VdWContact |
| THR 15 | NTc.Cm15 | PRO 26 | - | VdWContact |
| TRP 17 | NTc.Cm13 | TYR 19 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | TYR 19 | - | VdWContact |
| TRP 17 | NTc.Cm13 | GLU 23 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | GLU 23 | - | VdWContact |
| TRP 17 | NTc.Cm13 | ILE 25 | - | Hydrophobic |
| GLN 18 | NTc.Cm12 | TYR 19 | - | HBAcceptor |
| GLN 18 | NTc.Cm12 | TYR 19 | - | VdWContact |
| ILE 19 | NTc.Cm11 | TYR 19 | - | Hydrophobic |
| ILE 19 | NTc.Cm11 | TYR 19 | - | VdWContact |
| PRO 20 | NTc.Cm10 | TYR 19 | - | Hydrophobic |
| PRO 20 | NTc.Cm10 | TYR 19 | - | VdWContact |
| LYS 22 | NTc.Cm8 | ASP 12 | - | Cationic |
| LYS 22 | NTc.Cm8 | ASP 12 | - | HBDonor |
| LYS 22 | NTc.Cm8 | ASP 12 | - | VdWContact |
| PHE 23 | NTc.Cm7 | ASP 12 | - | Hydrophobic |
| PHE 23 | NTc.Cm7 | ASP 12 | - | VdWContact |
| PHE 23 | NTc.Cm7 | ILE 15 | - | Hydrophobic |
| PHE 23 | NTc.Cm7 | TYR 16 | - | Hydrophobic |
| PHE 23 | NTc.Cm7 | TYR 16 | - | PiStacking |
| PHE 23 | NTc.Cm7 | TYR 16 | - | VdWContact |
| GLU 29 | NTc.Cm1 | ARG 182 | - | HBAcceptor |
| GLU 29 | NTc.Cm1 | ARG 182 | - | VdWContact |
| SER 31 | CX.5 | GLU 181 | - | HBDonor |
| SER 31 | CX.5 | GLU 181 | - | VdWContact |
| PRO 32 | cxb1.1 | GLU 181 | - | VdWContact |
| GLN 33 | cxb1.2 | TYR 186 | - | VdWContact |
| GLN 33 | cxb1.2 | LYS 188 | 45.51x51 | Hydrophobic |
| GLN 33 | cxb1.2 | LYS 188 | 45.51x51 | VdWContact |
| PRO 35 | cxb1.6 | VAL 268 | 6.61x61 | Hydrophobic |
| PRO 35 | cxb1.6 | GLU 269 | 6.62x62 | VdWContact |
| LYS 36 | cxb1.7 | GLU 271 | 6.64x64 | Cationic |
| LYS 36 | cxb1.7 | GLU 271 | 6.64x64 | HBDonor |
| LYS 36 | cxb1.7 | GLU 271 | 6.64x64 | VdWContact |
| LYS 36 | cxb1.7 | GLN 274 | - | VdWContact |
| ILE 40 | cxb1.14 | PRO 28 | - | Hydrophobic |
| THR 43 | B1.1 | TYR 16 | - | HBAcceptor |
| THR 43 | B1.1 | TYR 16 | - | VdWContact |
| THR 43 | B1.1 | TYR 20 | - | Hydrophobic |
| THR 43 | B1.1 | TYR 20 | - | VdWContact |
| LYS 44 | B1.2 | ASP 12 | - | Cationic |
| LYS 44 | B1.2 | TYR 16 | - | Hydrophobic |
| ARG 45 | B1.3 | GLU 13 | - | Cationic |
| ARG 45 | B1.3 | GLU 13 | - | HBDonor |
| ARG 45 | B1.3 | GLU 13 | - | VdWContact |
| ARG 45 | B1.3 | TYR 16 | - | HBDonor |
| ARG 45 | B1.3 | TYR 16 | - | Hydrophobic |
| ARG 45 | B1.3 | TYR 16 | - | VdWContact |
| ARG 47 | B1.5 | TYR 20 | - | HBDonor |
| ARG 47 | B1.5 | TYR 20 | - | Hydrophobic |
| ARG 47 | B1.5 | TYR 20 | - | VdWContact |
| GLN 48 | B1.6 | PRO 28 | - | Hydrophobic |
| ILE 49 | B1.7 | TYR 20 | - | Hydrophobic |
| ILE 49 | B1.7 | TYR 20 | - | VdWContact |
| ILE 49 | B1.7 | ILE 25 | - | Hydrophobic |
| ILE 49 | B1.7 | ILE 25 | - | VdWContact |
| CYS 50 | b1b2.4 | PRO 26 | - | HBDonor |
| CYS 50 | b1b2.4 | PRO 26 | - | Hydrophobic |
| CYS 50 | b1b2.4 | PRO 26 | - | VdWContact |
| CYS 50 | b1b2.4 | PRO 28 | - | VdWContact |
