Predicted complex interactions
CCL19_HUMAN + CCR4
SUMMARY
- Chemokine
- CCL19_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR4 View partner entry
- Partner description
- UniProt: P51679; Gene: ccr4_human; Family: Chemokine
- Interactions detected
- 82
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm28 | TYR 46 | 1.39x39 | HBDonor |
| GLY 1 | NTc.Cm28 | TYR 46 | 1.39x39 | VdWContact |
| GLY 1 | NTc.Cm28 | GLU 290 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm28 | GLU 290 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm28 | GLU 290 | 7.39x38 | VdWContact |
| GLY 1 | NTc.Cm28 | PHE 294 | 7.43x42 | VdWContact |
| THR 2 | NTc.Cm27 | TRP 95 | 2.60x60 | Hydrophobic |
| THR 2 | NTc.Cm27 | TYR 98 | 2.63x63 | Hydrophobic |
| THR 2 | NTc.Cm27 | TYR 98 | 2.63x63 | VdWContact |
| ASN 3 | NTc.Cm26 | LYS 35 | 1.28x28 | HBDonor |
| ASN 3 | NTc.Cm26 | LYS 35 | 1.28x28 | VdWContact |
| ASN 3 | NTc.Cm26 | GLU 39 | 1.32x32 | VdWContact |
| ASN 3 | NTc.Cm26 | LEU 42 | 1.35x35 | Hydrophobic |
| ASN 3 | NTc.Cm26 | ALA 99 | 2.64x64 | HBDonor |
| ASN 3 | NTc.Cm26 | ALA 99 | 2.64x64 | Hydrophobic |
| ASN 3 | NTc.Cm26 | ALA 99 | 2.64x64 | VdWContact |
| ASN 3 | NTc.Cm26 | GLN 287 | 7.36x35 | VdWContact |
| ASP 4 | NTc.Cm25 | TYR 98 | 2.63x63 | HBAcceptor |
| ASP 4 | NTc.Cm25 | TYR 98 | 2.63x63 | VdWContact |
| ALA 5 | NTc.Cm24 | LYS 31 | 1.24x24 | Hydrophobic |
| ALA 5 | NTc.Cm24 | LYS 31 | 1.24x24 | VdWContact |
| ALA 5 | NTc.Cm24 | ILE 34 | 1.27x27 | Hydrophobic |
| ALA 5 | NTc.Cm24 | LYS 35 | 1.28x28 | VdWContact |
| ALA 5 | NTc.Cm24 | ASP 283 | 7.32x31 | Hydrophobic |
| GLU 6 | NTc.Cm23 | LYS 31 | 1.24x24 | VdWContact |
| GLU 6 | NTc.Cm23 | LYS 188 | 45.51x51 | Anionic |
| GLU 6 | NTc.Cm23 | LYS 188 | 45.51x51 | HBAcceptor |
| GLU 6 | NTc.Cm23 | LYS 188 | 45.51x51 | VdWContact |
| ASP 7 | NTc.Cm22 | CYS 29 | - | VdWContact |
| ASP 7 | NTc.Cm22 | THR 30 | - | VdWContact |
| ASP 7 | NTc.Cm22 | LYS 31 | 1.24x24 | HBAcceptor |
| ASP 7 | NTc.Cm22 | LYS 31 | 1.24x24 | VdWContact |
| CYS 8 | NTc.Cm21 | CYS 29 | - | HBAcceptor |
| CYS 8 | NTc.Cm21 | CYS 29 | - | VdWContact |
| LEU 10 | NTc.Cm19 | CYS 29 | - | Hydrophobic |
| LEU 10 | NTc.Cm19 | CYS 276 | 7.25x24 | Hydrophobic |
| LEU 10 | NTc.Cm19 | GLU 279 | 7.28x27 | VdWContact |
| SER 11 | NTc.Cm18 | PRO 26 | - | VdWContact |
| THR 13 | NTc.Cm16 | ILE 25 | - | Hydrophobic |
| THR 13 | NTc.Cm16 | ILE 25 | - | VdWContact |
| THR 13 | NTc.Cm16 | PRO 26 | - | VdWContact |
| ILE 17 | NTc.Cm12 | TYR 22 | - | Hydrophobic |
| ILE 17 | NTc.Cm12 | ILE 25 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | TYR 22 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | TYR 22 | - | VdWContact |
| TYR 20 | NTc.Cm9 | ASN 18 | - | VdWContact |
| ILE 21 | NTc.Cm8 | TYR 22 | - | Hydrophobic |
| ILE 21 | NTc.Cm8 | TYR 22 | - | VdWContact |
| HIS 26 | NTc.Cm3 | ARG 182 | - | HBAcceptor |
| HIS 26 | NTc.Cm3 | ARG 182 | - | PiCation |
| HIS 26 | NTc.Cm3 | ARG 182 | - | VdWContact |
| LEU 28 | NTc.Cm1 | PRO 28 | - | Hydrophobic |
| LEU 28 | NTc.Cm1 | ARG 182 | - | VdWContact |
| LYS 31 | cxb1.1 | LYS 190 | - | HBAcceptor |
| LYS 31 | cxb1.1 | LYS 190 | - | VdWContact |
| ASP 32 | cxb1.2 | LYS 188 | 45.51x51 | HBAcceptor |
| ASP 32 | cxb1.2 | LYS 188 | 45.51x51 | VdWContact |
| GLY 33 | cxb1.5 | LYS 199 | 5.35x36 | HBAcceptor |
| ARG 35 | cxb1.8 | VAL 268 | 6.61x61 | VdWContact |
| ARG 35 | cxb1.8 | GLU 269 | 6.62x62 | Cationic |
| ARG 35 | cxb1.8 | GLU 269 | 6.62x62 | HBDonor |
| ARG 35 | cxb1.8 | GLU 269 | 6.62x62 | VdWContact |
| ARG 35 | cxb1.8 | GLU 279 | 7.28x27 | Cationic |
| ARG 35 | cxb1.8 | GLU 279 | 7.28x27 | HBDonor |
| ARG 35 | cxb1.8 | GLU 279 | 7.28x27 | VdWContact |
| VAL 40 | cxb1.15 | PRO 28 | - | Hydrophobic |
| ARG 45 | B1.4 | TYR 19 | - | VdWContact |
| ARG 47 | B1.6 | TYR 19 | - | CationPi |
| ARG 47 | B1.6 | TYR 19 | - | VdWContact |
| ARG 47 | B1.6 | GLU 23 | - | Cationic |
| ARG 47 | B1.6 | GLU 23 | - | HBDonor |
| ARG 47 | B1.6 | GLU 23 | - | VdWContact |
| GLN 48 | B1.7 | LYS 27 | - | VdWContact |
| GLN 48 | B1.7 | PRO 28 | - | Hydrophobic |
| LEU 49 | b1b2.4 | TYR 22 | - | Hydrophobic |
| LEU 49 | b1b2.4 | ILE 25 | - | Hydrophobic |
| LEU 49 | b1b2.4 | ILE 25 | - | VdWContact |
| CYS 50 | b1b2.6 | PRO 26 | - | HBDonor |
| CYS 50 | b1b2.6 | PRO 26 | - | Hydrophobic |
| CYS 50 | b1b2.6 | PRO 26 | - | VdWContact |
| CYS 50 | b1b2.6 | LYS 27 | - | VdWContact |
| CYS 50 | b1b2.6 | PRO 28 | - | VdWContact |
