Predicted complex interactions
CCL25_HUMAN + CCR4
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR4 View partner entry
- Partner description
- UniProt: P51679; Gene: ccr4_human; Family: Chemokine
- Interactions detected
- 101
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | TRP 95 | 2.60x60 | Hydrophobic |
| GLN 1 | NTc.Cm29 | SER 114 | 3.29x29 | HBDonor |
| GLN 1 | NTc.Cm29 | SER 114 | 3.29x29 | VdWContact |
| GLN 1 | NTc.Cm29 | GLU 290 | 7.39x38 | Cationic |
| GLN 1 | NTc.Cm29 | GLU 290 | 7.39x38 | HBDonor |
| GLN 1 | NTc.Cm29 | GLU 290 | 7.39x38 | VdWContact |
| GLY 2 | NTc.Cm28 | GLN 287 | 7.36x35 | HBAcceptor |
| GLY 2 | NTc.Cm28 | GLN 287 | 7.36x35 | VdWContact |
| VAL 3 | NTc.Cm27 | TYR 98 | 2.63x63 | Hydrophobic |
| VAL 3 | NTc.Cm27 | TYR 186 | - | Hydrophobic |
| PHE 4 | NTc.Cm26 | LYS 31 | 1.24x24 | Hydrophobic |
| PHE 4 | NTc.Cm26 | LYS 31 | 1.24x24 | VdWContact |
| PHE 4 | NTc.Cm26 | ILE 34 | 1.27x27 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ASP 283 | 7.32x31 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ASP 283 | 7.32x31 | VdWContact |
| PHE 4 | NTc.Cm26 | ILE 286 | 7.35x34 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ILE 286 | 7.35x34 | VdWContact |
| PHE 4 | NTc.Cm26 | GLN 287 | 7.36x35 | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLN 287 | 7.36x35 | VdWContact |
| GLU 5 | NTc.Cm25 | LYS 31 | 1.24x24 | VdWContact |
| GLU 5 | NTc.Cm25 | TYR 186 | - | Hydrophobic |
| GLU 5 | NTc.Cm25 | LYS 188 | 45.51x51 | Anionic |
| GLU 5 | NTc.Cm25 | LYS 188 | 45.51x51 | VdWContact |
| ASP 6 | NTc.Cm24 | PRO 28 | - | Hydrophobic |
| ASP 6 | NTc.Cm24 | THR 30 | - | VdWContact |
| ASP 6 | NTc.Cm24 | LYS 31 | 1.24x24 | HBAcceptor |
| ASP 6 | NTc.Cm24 | LYS 31 | 1.24x24 | VdWContact |
| CYS 7 | NTc.Cm23 | CYS 29 | - | HBAcceptor |
| CYS 7 | NTc.Cm23 | CYS 29 | - | HBDonor |
| CYS 7 | NTc.Cm23 | CYS 29 | - | VdWContact |
| CYS 8 | NTc.Cm22 | PRO 28 | - | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 29 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 276 | 7.25x24 | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 276 | 7.25x24 | VdWContact |
| LEU 9 | NTc.Cm21 | GLU 279 | 7.28x27 | Hydrophobic |
| LEU 9 | NTc.Cm21 | GLU 279 | 7.28x27 | VdWContact |
| HIS 12 | NTc.Cm18 | TYR 19 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | ILE 25 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | ILE 25 | - | VdWContact |
| HIS 12 | NTc.Cm18 | PRO 26 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | PRO 26 | - | VdWContact |
| ILE 15 | NTc.Cm15 | TYR 19 | - | Hydrophobic |
| ALA 18 | NTc.Cm12 | ASP 12 | - | VdWContact |
| ALA 18 | NTc.Cm12 | ILE 15 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | TYR 16 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | TYR 16 | - | VdWContact |
| VAL 19 | NTc.Cm11 | TYR 19 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | TYR 19 | - | VdWContact |
| ARG 21 | NTc.Cm9 | ASP 12 | - | Cationic |
| ARG 21 | NTc.Cm9 | ASP 12 | - | VdWContact |
| ARG 22 | NTc.Cm8 | ASP 12 | - | HBDonor |
| ARG 22 | NTc.Cm8 | ASP 12 | - | VdWContact |
| ARG 22 | NTc.Cm8 | GLU 13 | - | Cationic |
| ARG 22 | NTc.Cm8 | GLU 13 | - | HBDonor |
| ARG 22 | NTc.Cm8 | GLU 13 | - | VdWContact |
| ARG 22 | NTc.Cm8 | TYR 16 | - | Hydrophobic |
| ARG 22 | NTc.Cm8 | TYR 16 | - | VdWContact |
| ARG 27 | NTc.Cm3 | GLU 181 | - | Cationic |
| ARG 27 | NTc.Cm3 | GLU 181 | - | HBDonor |
| ARG 27 | NTc.Cm3 | GLU 181 | - | VdWContact |
| GLU 30 | CX.1 | LYS 190 | - | Anionic |
| GLU 30 | CX.1 | LYS 190 | - | HBAcceptor |
| GLU 30 | CX.1 | LYS 190 | - | VdWContact |
| VAL 31 | CX.5 | SER 195 | 5.31x32 | VdWContact |
| VAL 31 | CX.5 | LYS 199 | 5.35x36 | Hydrophobic |
| SER 32 | cxb1.1 | LYS 188 | 45.51x51 | HBAcceptor |
| SER 32 | cxb1.1 | LYS 188 | 45.51x51 | VdWContact |
| SER 32 | cxb1.1 | THR 189 | 45.52x52 | VdWContact |
| GLY 33 | cxb1.2 | THR 189 | 45.52x52 | HBDonor |
| GLY 33 | cxb1.2 | LYS 199 | 5.35x36 | VdWContact |
| SER 34 | cxb1.5 | LYS 31 | 1.24x24 | HBAcceptor |
| SER 34 | cxb1.5 | LYS 31 | 1.24x24 | VdWContact |
| ASN 36 | cxb1.8 | LYS 199 | 5.35x36 | VdWContact |
| ASN 36 | cxb1.8 | GLU 269 | 6.62x62 | Hydrophobic |
| ASN 36 | cxb1.8 | GLU 279 | 7.28x27 | HBDonor |
| ASN 36 | cxb1.8 | GLU 279 | 7.28x27 | VdWContact |
| ILE 41 | cxb1.16 | PRO 28 | - | Hydrophobic |
| TYR 43 | B1.2 | ARG 182 | - | VdWContact |
| LEU 44 | B1.3 | TYR 19 | - | Hydrophobic |
| LEU 44 | B1.3 | TYR 20 | - | Hydrophobic |
| LEU 44 | B1.3 | TYR 20 | - | VdWContact |
| PRO 45 | B1.4 | TYR 16 | - | VdWContact |
| LYS 46 | B1.5 | TYR 16 | - | Hydrophobic |
| LYS 46 | B1.5 | TYR 20 | - | Hydrophobic |
| LYS 46 | B1.5 | TYR 20 | - | VdWContact |
| ARG 49 | b1b2.1 | TYR 19 | - | VdWContact |
| ARG 49 | b1b2.1 | TYR 20 | - | HBDonor |
| ARG 49 | b1b2.1 | TYR 20 | - | Hydrophobic |
| ARG 49 | b1b2.1 | TYR 20 | - | VdWContact |
| ARG 49 | b1b2.1 | TYR 22 | - | HBDonor |
| ARG 49 | b1b2.1 | TYR 22 | - | VdWContact |
| LYS 50 | b1b2.2 | LYS 27 | - | VdWContact |
| LYS 50 | b1b2.2 | PRO 28 | - | Hydrophobic |
| LYS 50 | b1b2.2 | PRO 28 | - | VdWContact |
| VAL 51 | b1b2.3 | TYR 19 | - | Hydrophobic |
| VAL 51 | b1b2.3 | TYR 19 | - | VdWContact |
| VAL 51 | b1b2.3 | ILE 25 | - | Hydrophobic |
| CYS 52 | b1b2.4 | PRO 26 | - | HBDonor |
| CYS 52 | b1b2.4 | PRO 26 | - | VdWContact |
| CYS 52 | b1b2.4 | LYS 27 | - | VdWContact |
| CYS 52 | b1b2.4 | PRO 28 | - | VdWContact |
