Predicted complex interactions
CXCL4_HUMAN + ACKR1
SUMMARY
- Chemokine
- CXCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR1 View partner entry
- Partner description
- UniProt: Q16570; Gene: ackr1_human; Family: Chemokine
- Interactions detected
- 108
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLU 3 | NTc.Cm38 | LEU 10 | - | Hydrophobic |
| GLU 3 | NTc.Cm38 | SER 11 | - | HBAcceptor |
| GLU 3 | NTc.Cm38 | SER 11 | - | VdWContact |
| GLU 3 | NTc.Cm38 | SER 13 | - | HBAcceptor |
| GLU 3 | NTc.Cm38 | SER 13 | - | VdWContact |
| GLU 3 | NTc.Cm38 | THR 14 | - | HBAcceptor |
| GLU 3 | NTc.Cm38 | THR 14 | - | VdWContact |
| ASP 5 | NTc.Cm36 | GLY 192 | - | VdWContact |
| ASP 5 | NTc.Cm36 | LEU 194 | - | Hydrophobic |
| GLY 6 | NTc.Cm35 | ASN 55 | - | HBAcceptor |
| ASP 7 | NTc.Cm34 | SER 53 | - | HBAcceptor |
| ASP 7 | NTc.Cm34 | SER 53 | - | VdWContact |
| LEU 8 | NTc.Cm33 | ARG 267 | 6.62x62 | HBAcceptor |
| LEU 8 | NTc.Cm33 | ARG 267 | 6.62x62 | VdWContact |
| LEU 8 | NTc.Cm33 | ASP 283 | 7.32x31 | Hydrophobic |
| GLN 9 | NTc.Cm32 | GLN 279 | 7.28x27 | Hydrophobic |
| GLN 9 | NTc.Cm32 | GLN 279 | 7.28x27 | VdWContact |
| GLN 9 | NTc.Cm32 | LEU 282 | 7.31x30 | VdWContact |
| GLN 9 | NTc.Cm32 | ASP 283 | 7.32x31 | HBDonor |
| GLN 9 | NTc.Cm32 | ASP 283 | 7.32x31 | VdWContact |
| CYS 10 | NTc.Cm31 | GLN 279 | 7.28x27 | HBAcceptor |
| CYS 10 | NTc.Cm31 | GLN 279 | 7.28x27 | VdWContact |
| LEU 11 | NTc.Cm30 | PRO 50 | - | Hydrophobic |
| LEU 11 | NTc.Cm30 | CYS 51 | - | HBAcceptor |
| LEU 11 | NTc.Cm30 | CYS 51 | - | VdWContact |
| LEU 11 | NTc.Cm30 | HIS 52 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | CYS 51 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | LEU 273 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | GLN 279 | 7.28x27 | Hydrophobic |
| VAL 13 | NTc.Cm28 | GLN 279 | 7.28x27 | VdWContact |
| LYS 14 | NTc.Cm27 | ALA 47 | - | Hydrophobic |
| LYS 14 | NTc.Cm27 | ALA 47 | - | VdWContact |
| LYS 14 | NTc.Cm27 | SER 274 | - | HBDonor |
| LYS 14 | NTc.Cm27 | SER 274 | - | VdWContact |
| THR 16 | NTc.Cm25 | ALA 48 | - | Hydrophobic |
| GLN 18 | NTc.Cm23 | PHE 36 | - | Hydrophobic |
| GLN 18 | NTc.Cm23 | PHE 36 | - | VdWContact |
| GLN 18 | NTc.Cm23 | TYR 41 | - | VdWContact |
| GLN 18 | NTc.Cm23 | ASN 44 | - | HBAcceptor |
| VAL 19 | NTc.Cm22 | TYR 41 | - | VdWContact |
| VAL 19 | NTc.Cm22 | LEU 45 | - | Hydrophobic |
| ARG 20 | NTc.Cm21 | ASP 34 | - | Hydrophobic |
| ARG 20 | NTc.Cm21 | PHE 36 | - | HBDonor |
| ARG 20 | NTc.Cm21 | PHE 36 | - | Hydrophobic |
| ARG 20 | NTc.Cm21 | PHE 36 | - | VdWContact |
| ARG 20 | NTc.Cm21 | ASP 38 | - | Cationic |
| ARG 20 | NTc.Cm21 | ASP 38 | - | HBDonor |
| ARG 20 | NTc.Cm21 | ASP 38 | - | VdWContact |
| ARG 20 | NTc.Cm21 | TYR 41 | - | HBDonor |
| ARG 20 | NTc.Cm21 | TYR 41 | - | Hydrophobic |
| ARG 20 | NTc.Cm21 | TYR 41 | - | VdWContact |
| PRO 21 | NTc.Cm20 | PHE 22 | - | Hydrophobic |
| PRO 21 | NTc.Cm20 | PHE 22 | - | VdWContact |
| PRO 21 | NTc.Cm20 | TRP 26 | - | Hydrophobic |
| PRO 21 | NTc.Cm20 | TRP 26 | - | VdWContact |
| PRO 21 | NTc.Cm20 | ASP 34 | - | VdWContact |
| ILE 24 | NTc.Cm17 | PHE 22 | - | Hydrophobic |
| ILE 24 | NTc.Cm17 | PHE 22 | - | VdWContact |
| THR 25 | NTc.Cm16 | PHE 22 | - | HBAcceptor |
| THR 25 | NTc.Cm16 | PHE 22 | - | VdWContact |
| SER 26 | NTc.Cm15 | GLN 19 | - | HBAcceptor |
| SER 26 | NTc.Cm15 | GLN 19 | - | VdWContact |
| SER 26 | NTc.Cm15 | LEU 20 | - | VdWContact |
| LEU 27 | NTc.Cm14 | GLN 19 | - | VdWContact |
| LEU 27 | NTc.Cm14 | LEU 20 | - | HBAcceptor |
| LEU 27 | NTc.Cm14 | LEU 20 | - | HBDonor |
| LEU 27 | NTc.Cm14 | LEU 20 | - | VdWContact |
| LEU 27 | NTc.Cm14 | PHE 22 | - | Hydrophobic |
| LEU 27 | NTc.Cm14 | PHE 22 | - | VdWContact |
| GLU 28 | NTc.Cm13 | SER 17 | - | HBAcceptor |
| GLU 28 | NTc.Cm13 | SER 17 | - | VdWContact |
| GLU 28 | NTc.Cm13 | SER 18 | - | VdWContact |
| VAL 29 | NTc.Cm12 | SER 17 | - | VdWContact |
| VAL 29 | NTc.Cm12 | SER 18 | - | HBAcceptor |
| VAL 29 | NTc.Cm12 | SER 18 | - | HBDonor |
| VAL 29 | NTc.Cm12 | SER 18 | - | VdWContact |
| LYS 31 | NTc.Cm10 | ASN 16 | - | HBDonor |
| LYS 31 | NTc.Cm10 | ASN 16 | - | Hydrophobic |
| LYS 31 | NTc.Cm10 | ASN 16 | - | VdWContact |
| PRO 34 | NTc.Cm7 | SER 191 | - | VdWContact |
| PRO 34 | NTc.Cm7 | TYR 199 | - | HBAcceptor |
| PRO 34 | NTc.Cm7 | TYR 199 | - | VdWContact |
| HIS 35 | NTc.Cm6 | THR 196 | 45.51x51 | Hydrophobic |
| HIS 35 | NTc.Cm6 | THR 196 | 45.51x51 | VdWContact |
| HIS 35 | NTc.Cm6 | ARG 267 | 6.62x62 | VdWContact |
| PRO 37 | NTc.Cm4 | TYR 199 | - | VdWContact |
| THR 38 | NTc.Cm3 | LYS 269 | 6.64x64 | VdWContact |
| ILE 42 | CX.4 | PRO 50 | - | Hydrophobic |
| LEU 45 | cxb1.2 | LEU 45 | - | Hydrophobic |
| LYS 46 | cxb1.5 | GLU 23 | - | Cationic |
| LYS 46 | cxb1.5 | GLU 23 | - | HBDonor |
| LYS 46 | cxb1.5 | GLU 23 | - | VdWContact |
| LYS 50 | cxb1.11 | PRO 50 | - | Hydrophobic |
| LYS 50 | cxb1.11 | PRO 50 | - | VdWContact |
| ILE 51 | cxb1.14 | LEU 45 | - | Hydrophobic |
| ILE 51 | cxb1.14 | LEU 45 | - | VdWContact |
| CYS 52 | cxb1.15 | ALA 48 | - | HBDonor |
| CYS 52 | cxb1.15 | ALA 48 | - | VdWContact |
| LEU 59 | B1.6 | TRP 26 | - | Hydrophobic |
| LEU 59 | B1.6 | VAL 32 | - | Hydrophobic |
| LYS 62 | b1b2.6 | TYR 30 | - | Hydrophobic |
| LYS 62 | b1b2.6 | TYR 30 | - | VdWContact |
| ILE 63 | b1b2.7 | PHE 22 | - | Hydrophobic |
| ILE 63 | b1b2.7 | PHE 22 | - | VdWContact |
| ILE 63 | b1b2.7 | VAL 25 | - | Hydrophobic |
| ILE 63 | b1b2.7 | VAL 25 | - | VdWContact |
| LEU 67 | b1b2.12 | LEU 20 | - | Hydrophobic |
| LEU 67 | b1b2.12 | LEU 20 | - | VdWContact |
