Predicted complex interactions
CCL27_HUMAN + CCR4
SUMMARY
- Chemokine
- CCL27_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR4 View partner entry
- Partner description
- UniProt: P51679; Gene: ccr4_human; Family: Chemokine
- Interactions detected
- 84
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PRO 5 | NTc.Cm28 | ARG 182 | - | HBAcceptor |
| PRO 5 | NTc.Cm28 | ARG 182 | - | VdWContact |
| THR 7 | NTc.Cm26 | LYS 31 | 1.24x24 | HBAcceptor |
| THR 7 | NTc.Cm26 | LYS 31 | 1.24x24 | VdWContact |
| ALA 8 | NTc.Cm25 | PRO 28 | - | Hydrophobic |
| ALA 8 | NTc.Cm25 | CYS 29 | - | VdWContact |
| CYS 9 | NTc.Cm24 | CYS 29 | - | HBAcceptor |
| CYS 9 | NTc.Cm24 | CYS 29 | - | HBDonor |
| CYS 9 | NTc.Cm24 | CYS 29 | - | VdWContact |
| CYS 9 | NTc.Cm24 | LYS 31 | 1.24x24 | Hydrophobic |
| CYS 9 | NTc.Cm24 | LYS 31 | 1.24x24 | VdWContact |
| THR 11 | NTc.Cm22 | CYS 29 | - | Hydrophobic |
| THR 11 | NTc.Cm22 | CYS 29 | - | VdWContact |
| THR 11 | NTc.Cm22 | CYS 276 | 7.25x24 | VdWContact |
| THR 11 | NTc.Cm22 | GLU 279 | 7.28x27 | Hydrophobic |
| THR 11 | NTc.Cm22 | GLU 279 | 7.28x27 | VdWContact |
| GLN 12 | NTc.Cm21 | PRO 26 | - | Hydrophobic |
| GLN 12 | NTc.Cm21 | PRO 26 | - | VdWContact |
| GLN 12 | NTc.Cm21 | GLN 274 | - | HBDonor |
| GLN 12 | NTc.Cm21 | GLN 274 | - | Hydrophobic |
| GLN 12 | NTc.Cm21 | GLN 274 | - | VdWContact |
| GLN 12 | NTc.Cm21 | ASP 275 | 7.24x23 | VdWContact |
| LEU 13 | NTc.Cm20 | GLU 271 | 6.64x64 | Hydrophobic |
| LEU 13 | NTc.Cm20 | GLU 271 | 6.64x64 | VdWContact |
| LEU 13 | NTc.Cm20 | GLN 274 | - | HBDonor |
| LEU 13 | NTc.Cm20 | GLN 274 | - | VdWContact |
| TYR 14 | NTc.Cm19 | ILE 25 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | PRO 26 | - | VdWContact |
| ARG 15 | NTc.Cm18 | GLU 271 | 6.64x64 | Cationic |
| ARG 15 | NTc.Cm18 | GLU 271 | 6.64x64 | HBDonor |
| ARG 15 | NTc.Cm18 | GLU 271 | 6.64x64 | VdWContact |
| LEU 18 | NTc.Cm15 | ILE 25 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | TYR 22 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | TYR 22 | - | VdWContact |
| LEU 22 | NTc.Cm11 | ILE 25 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | ILE 25 | - | VdWContact |
| GLU 30 | NTc.Cm3 | ARG 182 | - | Anionic |
| GLU 30 | NTc.Cm3 | ARG 182 | - | HBAcceptor |
| GLU 30 | NTc.Cm3 | ARG 182 | - | VdWContact |
| GLU 33 | CX.1 | LYS 190 | - | Anionic |
| GLU 33 | CX.1 | LYS 190 | - | HBAcceptor |
| GLU 33 | CX.1 | LYS 190 | - | VdWContact |
| ALA 34 | CX.5 | LYS 199 | 5.35x36 | HBAcceptor |
| ALA 34 | CX.5 | LYS 199 | 5.35x36 | VdWContact |
| ASP 35 | cxb1.1 | TYR 179 | - | HBAcceptor |
| ASP 35 | cxb1.1 | TYR 179 | - | VdWContact |
| ASP 35 | cxb1.1 | LYS 188 | 45.51x51 | VdWContact |
| ASP 35 | cxb1.1 | LYS 190 | - | Anionic |
| ASP 35 | cxb1.1 | LYS 190 | - | HBAcceptor |
| ASP 35 | cxb1.1 | LYS 190 | - | VdWContact |
| GLY 36 | cxb1.2 | LYS 188 | 45.51x51 | HBAcceptor |
| GLY 36 | cxb1.2 | LYS 188 | 45.51x51 | VdWContact |
| ASP 37 | cxb1.5 | LYS 31 | 1.24x24 | HBAcceptor |
| ASP 37 | cxb1.5 | LYS 31 | 1.24x24 | VdWContact |
| ASP 37 | cxb1.5 | TYR 186 | - | HBAcceptor |
| ASP 37 | cxb1.5 | TYR 186 | - | VdWContact |
| ASP 37 | cxb1.5 | LYS 188 | 45.51x51 | Anionic |
| ASP 37 | cxb1.5 | LYS 188 | 45.51x51 | VdWContact |
| HIS 39 | cxb1.7 | GLU 265 | 6.58x58 | Hydrophobic |
| HIS 39 | cxb1.7 | GLU 265 | 6.58x58 | VdWContact |
| HIS 39 | cxb1.7 | VAL 268 | 6.61x61 | Hydrophobic |
| HIS 39 | cxb1.7 | GLU 279 | 7.28x27 | Hydrophobic |
| HIS 39 | cxb1.7 | GLU 279 | 7.28x27 | VdWContact |
| HIS 39 | cxb1.7 | ASP 283 | 7.32x31 | HBDonor |
| HIS 39 | cxb1.7 | ASP 283 | 7.32x31 | VdWContact |
| LEU 40 | cxb1.8 | VAL 268 | 6.61x61 | VdWContact |
| LEU 40 | cxb1.8 | GLU 271 | 6.64x64 | Hydrophobic |
| LEU 40 | cxb1.8 | GLN 274 | - | Hydrophobic |
| VAL 44 | cxb1.15 | PRO 28 | - | Hydrophobic |
| LEU 47 | cxb1.18 | TYR 22 | - | Hydrophobic |
| LEU 47 | cxb1.18 | TYR 22 | - | VdWContact |
| ARG 50 | B1.2 | TYR 22 | - | CationPi |
| ARG 50 | B1.2 | TYR 22 | - | HBDonor |
| ARG 50 | B1.2 | TYR 22 | - | Hydrophobic |
| ARG 50 | B1.2 | TYR 22 | - | VdWContact |
| ARG 50 | B1.2 | GLU 23 | - | VdWContact |
| ARG 50 | B1.2 | LYS 27 | - | VdWContact |
| ILE 52 | B1.4 | ILE 25 | - | Hydrophobic |
| ILE 52 | B1.4 | ILE 25 | - | VdWContact |
| ILE 52 | B1.4 | PRO 26 | - | VdWContact |
| CYS 53 | B1.5 | PRO 26 | - | HBDonor |
| CYS 53 | B1.5 | PRO 26 | - | Hydrophobic |
| CYS 53 | B1.5 | PRO 26 | - | VdWContact |
| ILE 54 | B1.6 | ILE 25 | - | Hydrophobic |
