Predicted complex interactions
CCL4_HUMAN + CCR4
SUMMARY
- Chemokine
- CCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR4 View partner entry
- Partner description
- UniProt: P51679; Gene: ccr4_human; Family: Chemokine
- Interactions detected
- 113
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm33 | TRP 95 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm33 | TRP 95 | 2.60x60 | VdWContact |
| ALA 1 | NTc.Cm33 | SER 114 | 3.29x29 | HBDonor |
| ALA 1 | NTc.Cm33 | SER 114 | 3.29x29 | VdWContact |
| ALA 1 | NTc.Cm33 | CYS 187 | 45.50x50 | VdWContact |
| ALA 1 | NTc.Cm33 | LYS 188 | 45.51x51 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 46 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TRP 95 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TRP 95 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm32 | LYS 188 | 45.51x51 | HBAcceptor |
| PRO 2 | NTc.Cm32 | LYS 188 | 45.51x51 | VdWContact |
| PRO 2 | NTc.Cm32 | GLU 290 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm32 | PHE 294 | 7.43x42 | Hydrophobic |
| MET 3 | NTc.Cm31 | ILE 206 | 5.42x43 | Hydrophobic |
| MET 3 | NTc.Cm31 | LEU 262 | 6.55x55 | Hydrophobic |
| MET 3 | NTc.Cm31 | ILE 286 | 7.35x34 | Hydrophobic |
| MET 3 | NTc.Cm31 | GLU 290 | 7.39x38 | HBDonor |
| MET 3 | NTc.Cm31 | GLU 290 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm30 | GLN 287 | 7.36x35 | HBAcceptor |
| GLY 4 | NTc.Cm30 | GLN 287 | 7.36x35 | VdWContact |
| GLY 4 | NTc.Cm30 | GLU 290 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm30 | GLU 290 | 7.39x38 | VdWContact |
| SER 5 | NTc.Cm29 | LYS 188 | 45.51x51 | HBAcceptor |
| SER 5 | NTc.Cm29 | LYS 188 | 45.51x51 | VdWContact |
| ASP 6 | NTc.Cm28 | LYS 35 | 1.28x28 | Anionic |
| ASP 6 | NTc.Cm28 | LYS 35 | 1.28x28 | HBAcceptor |
| ASP 6 | NTc.Cm28 | LYS 35 | 1.28x28 | VdWContact |
| ASP 6 | NTc.Cm28 | TYR 98 | 2.63x63 | HBAcceptor |
| ASP 6 | NTc.Cm28 | TYR 98 | 2.63x63 | Hydrophobic |
| ASP 6 | NTc.Cm28 | TYR 98 | 2.63x63 | VdWContact |
| ASP 6 | NTc.Cm28 | HIS 184 | - | HBAcceptor |
| ASP 6 | NTc.Cm28 | HIS 184 | - | VdWContact |
| ASP 6 | NTc.Cm28 | TYR 186 | - | VdWContact |
| PRO 7 | NTc.Cm27 | ILE 34 | 1.27x27 | Hydrophobic |
| PRO 7 | NTc.Cm27 | LYS 35 | 1.28x28 | Hydrophobic |
| PRO 8 | NTc.Cm26 | LYS 31 | 1.24x24 | Hydrophobic |
| PRO 8 | NTc.Cm26 | LYS 31 | 1.24x24 | VdWContact |
| THR 9 | NTc.Cm25 | LYS 31 | 1.24x24 | HBAcceptor |
| THR 9 | NTc.Cm25 | LYS 31 | 1.24x24 | VdWContact |
| THR 9 | NTc.Cm25 | GLU 32 | 1.25x25 | HBAcceptor |
| THR 9 | NTc.Cm25 | GLU 32 | 1.25x25 | Hydrophobic |
| THR 9 | NTc.Cm25 | LYS 35 | 1.28x28 | Hydrophobic |
| ALA 10 | NTc.Cm24 | PRO 28 | - | Hydrophobic |
| ALA 10 | NTc.Cm24 | PRO 28 | - | VdWContact |
| ALA 10 | NTc.Cm24 | CYS 29 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 29 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 29 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 29 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 29 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | VAL 268 | 6.61x61 | Hydrophobic |
| PHE 13 | NTc.Cm21 | GLN 274 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | GLU 279 | 7.28x27 | Hydrophobic |
| PHE 13 | NTc.Cm21 | GLU 279 | 7.28x27 | VdWContact |
| SER 14 | NTc.Cm20 | PRO 26 | - | VdWContact |
| TYR 15 | NTc.Cm19 | PRO 26 | - | VdWContact |
| ARG 18 | NTc.Cm16 | TYR 19 | - | HBAcceptor |
| ARG 18 | NTc.Cm16 | TYR 19 | - | Hydrophobic |
| ARG 18 | NTc.Cm16 | TYR 19 | - | VdWContact |
| ARG 18 | NTc.Cm16 | GLU 23 | - | Cationic |
| ARG 18 | NTc.Cm16 | GLU 23 | - | HBDonor |
| ARG 18 | NTc.Cm16 | GLU 23 | - | VdWContact |
| LEU 20 | NTc.Cm14 | TYR 19 | - | Hydrophobic |
| LEU 20 | NTc.Cm14 | TYR 19 | - | VdWContact |
| PRO 21 | NTc.Cm13 | ILE 15 | - | Hydrophobic |
| PRO 21 | NTc.Cm13 | TYR 19 | - | Hydrophobic |
| ASN 23 | NTc.Cm11 | ASP 12 | - | HBDonor |
| ASN 23 | NTc.Cm11 | ASP 12 | - | VdWContact |
| PHE 24 | NTc.Cm10 | ASP 12 | - | VdWContact |
| PHE 24 | NTc.Cm10 | ILE 15 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | ILE 15 | - | VdWContact |
| PHE 24 | NTc.Cm10 | TYR 16 | - | HBAcceptor |
| PHE 24 | NTc.Cm10 | TYR 16 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | TYR 16 | - | VdWContact |
| PHE 24 | NTc.Cm10 | TYR 19 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | TYR 20 | - | Hydrophobic |
| TYR 29 | NTc.Cm5 | ARG 182 | - | VdWContact |
| GLU 30 | NTc.Cm4 | ARG 182 | - | VdWContact |
| SER 32 | NTc.Cm2 | GLU 181 | - | HBDonor |
| SER 32 | NTc.Cm2 | GLU 181 | - | VdWContact |
| SER 33 | NTc.Cm1 | GLU 181 | - | HBDonor |
| SER 33 | NTc.Cm1 | GLU 181 | - | VdWContact |
| SER 33 | NTc.Cm1 | LYS 190 | - | HBAcceptor |
| SER 33 | NTc.Cm1 | LYS 190 | - | VdWContact |
| LEU 34 | CX.1 | TYR 186 | - | Hydrophobic |
| LEU 34 | CX.1 | LYS 188 | 45.51x51 | Hydrophobic |
| CYS 35 | CX.5 | LYS 199 | 5.35x36 | HBAcceptor |
| CYS 35 | CX.5 | LYS 199 | 5.35x36 | VdWContact |
| GLN 37 | cxb1.2 | GLU 271 | 6.64x64 | HBDonor |
| GLN 37 | cxb1.2 | GLU 271 | 6.64x64 | VdWContact |
| VAL 41 | cxb1.8 | PRO 28 | - | Hydrophobic |
| VAL 41 | cxb1.8 | PRO 28 | - | VdWContact |
| THR 44 | cxb1.14 | TYR 16 | - | VdWContact |
| THR 44 | cxb1.14 | TYR 20 | - | HBDonor |
| THR 44 | cxb1.14 | TYR 20 | - | Hydrophobic |
| THR 44 | cxb1.14 | TYR 20 | - | VdWContact |
| LYS 45 | cxb1.15 | ASP 12 | - | Cationic |
| LYS 45 | cxb1.15 | TYR 16 | - | Hydrophobic |
| LYS 45 | cxb1.15 | TYR 16 | - | VdWContact |
| ARG 46 | cxb1.16 | GLU 13 | - | Cationic |
| ARG 46 | cxb1.16 | GLU 13 | - | HBDonor |
| ARG 46 | cxb1.16 | GLU 13 | - | VdWContact |
| ARG 46 | cxb1.16 | TYR 16 | - | Hydrophobic |
| ARG 46 | cxb1.16 | TYR 16 | - | VdWContact |
| LYS 48 | B1.2 | TYR 20 | - | Hydrophobic |
| LYS 48 | B1.2 | TYR 20 | - | VdWContact |
| GLN 49 | B1.3 | PRO 28 | - | Hydrophobic |
| VAL 50 | B1.4 | ILE 25 | - | Hydrophobic |
| VAL 50 | B1.4 | PRO 26 | - | VdWContact |
| CYS 51 | B1.5 | PRO 26 | - | HBDonor |
| CYS 51 | B1.5 | PRO 26 | - | Hydrophobic |
| CYS 51 | B1.5 | PRO 26 | - | VdWContact |
| CYS 51 | B1.5 | LYS 27 | - | VdWContact |
| CYS 51 | B1.5 | PRO 28 | - | VdWContact |
