Predicted complex interactions
CX3CL1_HUMAN + CCR4
SUMMARY
- Chemokine
- CX3CL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR4 View partner entry
- Partner description
- UniProt: P51679; Gene: ccr4_human; Family: Chemokine
- Interactions detected
- 106
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm37 | LYS 188 | 45.51x51 | VdWContact |
| GLN 1 | NTc.Cm37 | THR 189 | 45.52x52 | HBAcceptor |
| GLN 1 | NTc.Cm37 | THR 189 | 45.52x52 | Hydrophobic |
| GLN 1 | NTc.Cm37 | THR 189 | 45.52x52 | VdWContact |
| HIS 2 | NTc.Cm36 | TYR 46 | 1.39x39 | Hydrophobic |
| HIS 2 | NTc.Cm36 | TYR 46 | 1.39x39 | VdWContact |
| HIS 2 | NTc.Cm36 | TRP 95 | 2.60x60 | Hydrophobic |
| HIS 2 | NTc.Cm36 | TRP 95 | 2.60x60 | VdWContact |
| HIS 2 | NTc.Cm36 | TYR 117 | 3.32x32 | Hydrophobic |
| HIS 2 | NTc.Cm36 | GLU 290 | 7.39x38 | HBDonor |
| HIS 2 | NTc.Cm36 | GLU 290 | 7.39x38 | Hydrophobic |
| HIS 2 | NTc.Cm36 | GLU 290 | 7.39x38 | VdWContact |
| HIS 2 | NTc.Cm36 | PHE 294 | 7.43x42 | Hydrophobic |
| HIS 2 | NTc.Cm36 | PHE 294 | 7.43x42 | VdWContact |
| HIS 3 | NTc.Cm35 | ILE 206 | 5.42x43 | Hydrophobic |
| HIS 3 | NTc.Cm35 | LEU 262 | 6.55x55 | Hydrophobic |
| HIS 3 | NTc.Cm35 | ILE 286 | 7.35x34 | Hydrophobic |
| HIS 3 | NTc.Cm35 | GLU 290 | 7.39x38 | HBDonor |
| HIS 3 | NTc.Cm35 | GLU 290 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm34 | GLN 287 | 7.36x35 | VdWContact |
| GLY 4 | NTc.Cm34 | GLU 290 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm34 | GLU 290 | 7.39x38 | VdWContact |
| VAL 5 | NTc.Cm33 | LEU 42 | 1.35x35 | Hydrophobic |
| VAL 5 | NTc.Cm33 | TYR 46 | 1.39x39 | Hydrophobic |
| VAL 5 | NTc.Cm33 | TRP 95 | 2.60x60 | Hydrophobic |
| VAL 5 | NTc.Cm33 | TYR 98 | 2.63x63 | Hydrophobic |
| VAL 5 | NTc.Cm33 | ALA 99 | 2.64x64 | Hydrophobic |
| LYS 7 | NTc.Cm31 | GLU 39 | 1.32x32 | Cationic |
| LYS 7 | NTc.Cm31 | GLU 39 | 1.32x32 | HBDonor |
| LYS 7 | NTc.Cm31 | GLU 39 | 1.32x32 | VdWContact |
| LYS 7 | NTc.Cm31 | TYR 98 | 2.63x63 | VdWContact |
| LYS 7 | NTc.Cm31 | ALA 99 | 2.64x64 | HBDonor |
| LYS 7 | NTc.Cm31 | ALA 99 | 2.64x64 | VdWContact |
| LYS 7 | NTc.Cm31 | ASP 101 | 2.66x66 | HBDonor |
| LYS 7 | NTc.Cm31 | ASP 101 | 2.66x66 | VdWContact |
| LYS 7 | NTc.Cm31 | TYR 186 | - | Hydrophobic |
| ASN 9 | NTc.Cm29 | THR 30 | - | VdWContact |
| ASN 9 | NTc.Cm29 | LYS 31 | 1.24x24 | HBAcceptor |
| ASN 9 | NTc.Cm29 | LYS 31 | 1.24x24 | VdWContact |
| ASN 9 | NTc.Cm29 | GLU 32 | 1.25x25 | Hydrophobic |
| ASN 9 | NTc.Cm29 | GLU 32 | 1.25x25 | VdWContact |
| ILE 10 | NTc.Cm28 | PRO 28 | - | Hydrophobic |
| ILE 10 | NTc.Cm28 | PRO 28 | - | VdWContact |
| ILE 10 | NTc.Cm28 | CYS 29 | - | VdWContact |
| THR 11 | NTc.Cm27 | CYS 29 | - | HBAcceptor |
| THR 11 | NTc.Cm27 | CYS 29 | - | HBDonor |
| THR 11 | NTc.Cm27 | CYS 29 | - | VdWContact |
| THR 11 | NTc.Cm27 | LYS 31 | 1.24x24 | Hydrophobic |
| THR 11 | NTc.Cm27 | LYS 31 | 1.24x24 | VdWContact |
| LYS 14 | NTc.Cm24 | PRO 26 | - | Hydrophobic |
| LYS 14 | NTc.Cm24 | PRO 26 | - | VdWContact |
| LYS 14 | NTc.Cm24 | GLN 274 | - | VdWContact |
| MET 15 | NTc.Cm23 | PRO 26 | - | VdWContact |
| THR 16 | NTc.Cm22 | TYR 19 | - | HBAcceptor |
| THR 16 | NTc.Cm22 | TYR 19 | - | VdWContact |
| SER 17 | NTc.Cm21 | TYR 19 | - | HBDonor |
| SER 17 | NTc.Cm21 | TYR 19 | - | VdWContact |
| ILE 19 | NTc.Cm19 | TYR 19 | - | Hydrophobic |
| ILE 19 | NTc.Cm19 | TYR 19 | - | VdWContact |
| PRO 20 | NTc.Cm18 | ILE 15 | - | Hydrophobic |
| PRO 20 | NTc.Cm18 | ILE 15 | - | VdWContact |
| LEU 23 | NTc.Cm15 | ASP 12 | - | VdWContact |
| LEU 23 | NTc.Cm15 | ILE 15 | - | Hydrophobic |
| LEU 23 | NTc.Cm15 | TYR 16 | - | Hydrophobic |
| LEU 23 | NTc.Cm15 | TYR 16 | - | VdWContact |
| GLN 28 | NTc.Cm10 | ARG 182 | - | HBAcceptor |
| GLN 28 | NTc.Cm10 | ARG 182 | - | VdWContact |
| GLN 29 | NTc.Cm9 | ARG 182 | - | HBAcceptor |
| GLN 29 | NTc.Cm9 | ARG 182 | - | VdWContact |
| GLN 31 | NTc.Cm7 | GLU 181 | - | VdWContact |
| ALA 32 | NTc.Cm6 | TYR 179 | - | Hydrophobic |
| ALA 32 | NTc.Cm6 | TYR 179 | - | VdWContact |
| ALA 32 | NTc.Cm6 | GLU 181 | - | HBDonor |
| ALA 32 | NTc.Cm6 | GLU 181 | - | VdWContact |
| ALA 32 | NTc.Cm6 | LYS 188 | 45.51x51 | VdWContact |
| SER 33 | NTc.Cm5 | TYR 179 | - | VdWContact |
| SER 33 | NTc.Cm5 | LYS 188 | 45.51x51 | VdWContact |
| LYS 36 | NTc.Cm2 | GLU 271 | 6.64x64 | Cationic |
| LYS 36 | NTc.Cm2 | GLU 271 | 6.64x64 | HBDonor |
| LYS 36 | NTc.Cm2 | GLU 271 | 6.64x64 | VdWContact |
| ILE 40 | CX.3 | PRO 28 | - | Hydrophobic |
| ILE 40 | CX.3 | PRO 28 | - | VdWContact |
| THR 43 | cxb1.1 | TYR 20 | - | HBDonor |
| THR 43 | cxb1.1 | TYR 20 | - | Hydrophobic |
| THR 43 | cxb1.1 | TYR 20 | - | VdWContact |
| ARG 44 | cxb1.2 | ASP 12 | - | Cationic |
| ARG 44 | cxb1.2 | ASP 12 | - | HBDonor |
| ARG 44 | cxb1.2 | ASP 12 | - | VdWContact |
| ARG 44 | cxb1.2 | TYR 16 | - | HBDonor |
| ARG 44 | cxb1.2 | TYR 16 | - | Hydrophobic |
| ARG 44 | cxb1.2 | TYR 16 | - | VdWContact |
| GLN 45 | cxb1.5 | TYR 16 | - | Hydrophobic |
| GLN 45 | cxb1.5 | TYR 16 | - | VdWContact |
| ARG 47 | cxb1.8 | TYR 20 | - | Hydrophobic |
| ARG 47 | cxb1.8 | TYR 20 | - | VdWContact |
| LEU 48 | cxb1.10 | PRO 28 | - | Hydrophobic |
| LEU 48 | cxb1.10 | PRO 28 | - | VdWContact |
| PHE 49 | cxb1.11 | TYR 19 | - | Hydrophobic |
| PHE 49 | cxb1.11 | TYR 19 | - | VdWContact |
| PHE 49 | cxb1.11 | TYR 20 | - | Hydrophobic |
| PHE 49 | cxb1.11 | TYR 20 | - | VdWContact |
| PHE 49 | cxb1.11 | ILE 25 | - | Hydrophobic |
| PHE 49 | cxb1.11 | ILE 25 | - | VdWContact |
| CYS 50 | cxb1.14 | PRO 26 | - | HBDonor |
| CYS 50 | cxb1.14 | PRO 26 | - | VdWContact |
| CYS 50 | cxb1.14 | PRO 28 | - | VdWContact |
