Predicted complex interactions
CXCL10_HUMAN + CCR4
SUMMARY
- Chemokine
- CXCL10_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR4 View partner entry
- Partner description
- UniProt: P51679; Gene: ccr4_human; Family: Chemokine
- Interactions detected
- 86
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm29 | TRP 95 | 2.60x60 | Hydrophobic |
| VAL 1 | NTc.Cm29 | TRP 95 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm28 | TYR 46 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TRP 95 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TYR 117 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm28 | GLU 290 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm28 | PHE 294 | 7.43x42 | Hydrophobic |
| LEU 3 | NTc.Cm27 | LEU 42 | 1.35x35 | Hydrophobic |
| LEU 3 | NTc.Cm27 | TRP 95 | 2.60x60 | Hydrophobic |
| LEU 3 | NTc.Cm27 | TRP 95 | 2.60x60 | VdWContact |
| LEU 3 | NTc.Cm27 | TYR 98 | 2.63x63 | Hydrophobic |
| LEU 3 | NTc.Cm27 | TYR 98 | 2.63x63 | VdWContact |
| LEU 3 | NTc.Cm27 | ALA 99 | 2.64x64 | Hydrophobic |
| LEU 3 | NTc.Cm27 | ALA 99 | 2.64x64 | VdWContact |
| SER 4 | NTc.Cm26 | LYS 188 | 45.51x51 | VdWContact |
| ARG 5 | NTc.Cm25 | TYR 258 | 6.51x51 | HBDonor |
| ARG 5 | NTc.Cm25 | TYR 258 | 6.51x51 | VdWContact |
| ARG 5 | NTc.Cm25 | LEU 262 | 6.55x55 | VdWContact |
| ARG 5 | NTc.Cm25 | GLU 265 | 6.58x58 | Cationic |
| ARG 5 | NTc.Cm25 | GLU 265 | 6.58x58 | HBDonor |
| ARG 5 | NTc.Cm25 | GLU 265 | 6.58x58 | VdWContact |
| ARG 5 | NTc.Cm25 | ILE 286 | 7.35x34 | Hydrophobic |
| ARG 5 | NTc.Cm25 | ILE 286 | 7.35x34 | VdWContact |
| ARG 5 | NTc.Cm25 | GLU 290 | 7.39x38 | Cationic |
| THR 6 | NTc.Cm24 | LYS 188 | 45.51x51 | HBAcceptor |
| THR 6 | NTc.Cm24 | LYS 188 | 45.51x51 | Hydrophobic |
| THR 6 | NTc.Cm24 | LYS 188 | 45.51x51 | VdWContact |
| VAL 7 | NTc.Cm23 | LYS 31 | 1.24x24 | Hydrophobic |
| VAL 7 | NTc.Cm23 | LYS 31 | 1.24x24 | VdWContact |
| ARG 8 | NTc.Cm22 | LYS 31 | 1.24x24 | VdWContact |
| ARG 8 | NTc.Cm22 | VAL 268 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm22 | GLU 279 | 7.28x27 | Cationic |
| ARG 8 | NTc.Cm22 | GLU 279 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm22 | LEU 282 | 7.31x30 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 283 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 283 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm22 | ASP 283 | 7.32x31 | VdWContact |
| THR 10 | NTc.Cm20 | CYS 29 | - | HBAcceptor |
| THR 10 | NTc.Cm20 | CYS 29 | - | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 29 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | GLN 274 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | CYS 276 | 7.25x24 | Hydrophobic |
| ILE 12 | NTc.Cm18 | CYS 276 | 7.25x24 | VdWContact |
| ILE 12 | NTc.Cm18 | GLU 279 | 7.28x27 | Hydrophobic |
| SER 13 | NTc.Cm17 | PRO 26 | - | VdWContact |
| SER 15 | NTc.Cm15 | ILE 25 | - | VdWContact |
| SER 15 | NTc.Cm15 | PRO 26 | - | VdWContact |
| GLN 17 | NTc.Cm13 | SER 24 | - | HBDonor |
| GLN 17 | NTc.Cm13 | SER 24 | - | VdWContact |
| GLN 17 | NTc.Cm13 | ILE 25 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | ILE 25 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | ILE 25 | - | VdWContact |
| ASN 20 | NTc.Cm10 | ASN 18 | - | VdWContact |
| GLN 34 | cxb1.2 | TYR 179 | - | Hydrophobic |
| GLN 34 | cxb1.2 | TYR 179 | - | VdWContact |
| GLN 34 | cxb1.2 | LYS 188 | 45.51x51 | VdWContact |
| GLN 34 | cxb1.2 | LYS 190 | - | VdWContact |
| PHE 35 | cxb1.5 | TYR 179 | - | Hydrophobic |
| PHE 35 | cxb1.5 | TYR 179 | - | VdWContact |
| PHE 35 | cxb1.5 | TYR 186 | - | Hydrophobic |
| PHE 35 | cxb1.5 | TYR 186 | - | PiStacking |
| PHE 35 | cxb1.5 | TYR 186 | - | VdWContact |
| PHE 35 | cxb1.5 | LYS 188 | 45.51x51 | Hydrophobic |
| PHE 35 | cxb1.5 | LYS 188 | 45.51x51 | VdWContact |
| ARG 38 | cxb1.8 | GLU 271 | 6.64x64 | Cationic |
| ILE 42 | cxb1.15 | PRO 28 | - | Hydrophobic |
| MET 45 | B1.2 | TYR 22 | - | Hydrophobic |
| LYS 47 | B1.4 | TYR 19 | - | Hydrophobic |
| LYS 47 | B1.4 | TYR 19 | - | VdWContact |
| LYS 48 | B1.5 | GLU 23 | - | Cationic |
| GLU 50 | B1.7 | TYR 22 | - | VdWContact |
| GLU 50 | B1.7 | LYS 27 | - | Anionic |
| GLU 50 | B1.7 | LYS 27 | - | HBAcceptor |
| GLU 50 | B1.7 | LYS 27 | - | VdWContact |
| LYS 51 | b1b2.4 | PRO 28 | - | Hydrophobic |
| LYS 51 | b1b2.4 | PRO 28 | - | VdWContact |
| ARG 52 | b1b2.6 | GLU 23 | - | HBDonor |
| ARG 52 | b1b2.6 | GLU 23 | - | VdWContact |
| ARG 52 | b1b2.6 | ILE 25 | - | HBDonor |
| ARG 52 | b1b2.6 | ILE 25 | - | Hydrophobic |
| ARG 52 | b1b2.6 | ILE 25 | - | VdWContact |
| ARG 52 | b1b2.6 | PRO 26 | - | VdWContact |
| CYS 53 | b1b2.7 | PRO 26 | - | HBDonor |
| CYS 53 | b1b2.7 | PRO 26 | - | VdWContact |
| CYS 53 | b1b2.7 | PRO 28 | - | VdWContact |
| LEU 54 | b1b2.8 | ILE 25 | - | Hydrophobic |
