Predicted complex interactions
CXCL2_HUMAN + CCR4
SUMMARY
- Chemokine
- CXCL2_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR4 View partner entry
- Partner description
- UniProt: P51679; Gene: ccr4_human; Family: Chemokine
- Interactions detected
- 81
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm42 | TRP 95 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm42 | TRP 95 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm41 | TRP 95 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm41 | TRP 95 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm41 | TYR 117 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm41 | GLU 290 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm41 | PHE 294 | 7.43x42 | Hydrophobic |
| LEU 3 | NTc.Cm40 | LEU 262 | 6.55x55 | Hydrophobic |
| LEU 3 | NTc.Cm40 | LEU 262 | 6.55x55 | VdWContact |
| LEU 3 | NTc.Cm40 | ILE 286 | 7.35x34 | Hydrophobic |
| LEU 3 | NTc.Cm40 | GLU 290 | 7.39x38 | HBDonor |
| LEU 3 | NTc.Cm40 | GLU 290 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm39 | LEU 42 | 1.35x35 | Hydrophobic |
| ALA 4 | NTc.Cm39 | ILE 286 | 7.35x34 | VdWContact |
| ALA 4 | NTc.Cm39 | GLN 287 | 7.36x35 | Hydrophobic |
| ALA 4 | NTc.Cm39 | GLN 287 | 7.36x35 | VdWContact |
| ALA 4 | NTc.Cm39 | GLU 290 | 7.39x38 | HBDonor |
| ALA 4 | NTc.Cm39 | GLU 290 | 7.39x38 | VdWContact |
| THR 5 | NTc.Cm38 | TYR 98 | 2.63x63 | Hydrophobic |
| THR 5 | NTc.Cm38 | TYR 98 | 2.63x63 | VdWContact |
| THR 5 | NTc.Cm38 | ALA 99 | 2.64x64 | Hydrophobic |
| GLU 6 | NTc.Cm37 | LYS 188 | 45.51x51 | Hydrophobic |
| GLU 6 | NTc.Cm37 | LYS 188 | 45.51x51 | VdWContact |
| LEU 7 | NTc.Cm36 | LYS 31 | 1.24x24 | Hydrophobic |
| LEU 7 | NTc.Cm36 | ILE 34 | 1.27x27 | Hydrophobic |
| LEU 7 | NTc.Cm36 | LYS 35 | 1.28x28 | Hydrophobic |
| LEU 7 | NTc.Cm36 | LYS 35 | 1.28x28 | VdWContact |
| ARG 8 | NTc.Cm35 | LYS 31 | 1.24x24 | VdWContact |
| ARG 8 | NTc.Cm35 | GLU 265 | 6.58x58 | Cationic |
| ARG 8 | NTc.Cm35 | VAL 268 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm35 | GLU 279 | 7.28x27 | Cationic |
| ARG 8 | NTc.Cm35 | GLU 279 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm35 | LEU 282 | 7.31x30 | VdWContact |
| ARG 8 | NTc.Cm35 | ASP 283 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm35 | ASP 283 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm35 | ASP 283 | 7.32x31 | VdWContact |
| GLN 10 | NTc.Cm33 | PRO 28 | - | Hydrophobic |
| GLN 10 | NTc.Cm33 | PRO 28 | - | VdWContact |
| GLN 10 | NTc.Cm33 | CYS 29 | - | HBAcceptor |
| GLN 10 | NTc.Cm33 | CYS 29 | - | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 29 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | CYS 276 | 7.25x24 | Hydrophobic |
| LEU 12 | NTc.Cm31 | GLU 279 | 7.28x27 | VdWContact |
| GLN 13 | NTc.Cm30 | PRO 26 | - | Hydrophobic |
| GLN 13 | NTc.Cm30 | PRO 26 | - | VdWContact |
| LEU 15 | NTc.Cm28 | TYR 20 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | TYR 20 | - | VdWContact |
| LEU 15 | NTc.Cm28 | ILE 25 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | PRO 26 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | PRO 26 | - | VdWContact |
| GLY 17 | NTc.Cm26 | TYR 20 | - | VdWContact |
| HIS 19 | NTc.Cm24 | TYR 16 | - | Hydrophobic |
| LYS 21 | NTc.Cm22 | GLU 13 | - | Cationic |
| LYS 21 | NTc.Cm22 | GLU 13 | - | HBDonor |
| LYS 21 | NTc.Cm22 | GLU 13 | - | VdWContact |
| LYS 27 | NTc.Cm16 | ARG 182 | - | VdWContact |
| PRO 33 | NTc.Cm10 | TYR 179 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | TYR 179 | - | VdWContact |
| PRO 33 | NTc.Cm10 | TYR 186 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | LYS 188 | 45.51x51 | HBAcceptor |
| PRO 33 | NTc.Cm10 | LYS 188 | 45.51x51 | Hydrophobic |
| PRO 33 | NTc.Cm10 | LYS 188 | 45.51x51 | VdWContact |
| HIS 34 | NTc.Cm9 | TYR 186 | - | Hydrophobic |
| HIS 34 | NTc.Cm9 | LYS 188 | 45.51x51 | HBAcceptor |
| HIS 34 | NTc.Cm9 | LYS 188 | 45.51x51 | PiCation |
| HIS 34 | NTc.Cm9 | LYS 188 | 45.51x51 | VdWContact |
| ILE 41 | NTc.Cm2 | PRO 28 | - | Hydrophobic |
| LEU 44 | CX.4 | TYR 22 | - | Hydrophobic |
| LEU 44 | CX.4 | TYR 22 | - | VdWContact |
| LEU 44 | CX.4 | ILE 25 | - | Hydrophobic |
| ASN 46 | cxb1.1 | TYR 22 | - | VdWContact |
| GLN 48 | cxb1.5 | TYR 22 | - | VdWContact |
| LYS 49 | cxb1.6 | LYS 27 | - | VdWContact |
| LYS 49 | cxb1.6 | PRO 28 | - | Hydrophobic |
| ALA 50 | cxb1.8 | ILE 25 | - | Hydrophobic |
| ALA 50 | cxb1.8 | ILE 25 | - | VdWContact |
| ALA 50 | cxb1.8 | PRO 26 | - | VdWContact |
| CYS 51 | cxb1.10 | PRO 26 | - | HBDonor |
| CYS 51 | cxb1.10 | PRO 26 | - | VdWContact |
| MET 58 | B1.3 | TYR 16 | - | Hydrophobic |
| MET 58 | B1.3 | TYR 16 | - | VdWContact |
