Predicted complex interactions
CCL1_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 97
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LYS 1 | NTc.Cm32 | TYR 251 | 6.51x51 | HBDonor |
| LYS 1 | NTc.Cm32 | TYR 251 | 6.51x51 | VdWContact |
| LYS 1 | NTc.Cm32 | LEU 255 | 6.55x55 | Hydrophobic |
| LYS 1 | NTc.Cm32 | LEU 255 | 6.55x55 | VdWContact |
| LYS 1 | NTc.Cm32 | ASN 258 | 6.58x58 | VdWContact |
| LYS 1 | NTc.Cm32 | THR 259 | 6.59x59 | HBDonor |
| LYS 1 | NTc.Cm32 | THR 259 | 6.59x59 | VdWContact |
| LYS 1 | NTc.Cm32 | MET 279 | 7.35x34 | Hydrophobic |
| SER 2 | NTc.Cm31 | TYR 108 | 3.32x32 | VdWContact |
| SER 2 | NTc.Cm31 | GLU 283 | 7.39x38 | HBDonor |
| SER 2 | NTc.Cm31 | GLU 283 | 7.39x38 | VdWContact |
| SER 2 | NTc.Cm31 | MET 287 | 7.43x42 | VdWContact |
| MET 3 | NTc.Cm30 | THR 105 | 3.29x29 | Hydrophobic |
| MET 3 | NTc.Cm30 | THR 105 | 3.29x29 | VdWContact |
| MET 3 | NTc.Cm30 | PHE 109 | 3.33x33 | Hydrophobic |
| MET 3 | NTc.Cm30 | PHE 109 | 3.33x33 | VdWContact |
| MET 3 | NTc.Cm30 | THR 167 | 4.64x65 | VdWContact |
| GLN 4 | NTc.Cm29 | MET 279 | 7.35x34 | Hydrophobic |
| GLN 4 | NTc.Cm29 | MET 279 | 7.35x34 | VdWContact |
| GLN 4 | NTc.Cm29 | GLN 280 | 7.36x35 | VdWContact |
| GLN 4 | NTc.Cm29 | GLU 283 | 7.39x38 | HBDonor |
| GLN 4 | NTc.Cm29 | GLU 283 | 7.39x38 | VdWContact |
| VAL 5 | NTc.Cm28 | TYR 89 | 2.63x63 | Hydrophobic |
| VAL 5 | NTc.Cm28 | TYR 89 | 2.63x63 | VdWContact |
| VAL 5 | NTc.Cm28 | CYS 178 | 45.50x50 | VdWContact |
| VAL 5 | NTc.Cm28 | SER 179 | 45.51x51 | VdWContact |
| PRO 6 | NTc.Cm27 | TYR 89 | 2.63x63 | Hydrophobic |
| PRO 6 | NTc.Cm27 | TYR 89 | 2.63x63 | VdWContact |
| PHE 7 | NTc.Cm26 | LYS 26 | 1.28x28 | Hydrophobic |
| PHE 7 | NTc.Cm26 | LYS 26 | 1.28x28 | VdWContact |
| SER 8 | NTc.Cm25 | GLU 172 | - | VdWContact |
| ARG 9 | NTc.Cm24 | PRO 19 | - | Hydrophobic |
| ARG 9 | NTc.Cm24 | PRO 19 | - | VdWContact |
| ARG 9 | NTc.Cm24 | GLU 172 | - | HBDonor |
| ARG 9 | NTc.Cm24 | GLU 172 | - | VdWContact |
| CYS 10 | NTc.Cm23 | CYS 20 | - | HBAcceptor |
| CYS 10 | NTc.Cm23 | CYS 20 | - | VdWContact |
| CYS 10 | NTc.Cm23 | LYS 22 | 1.24x24 | Anionic |
| PHE 12 | NTc.Cm21 | CYS 20 | - | Hydrophobic |
| PHE 12 | NTc.Cm21 | CYS 20 | - | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 269 | 7.25x24 | Hydrophobic |
| PHE 12 | NTc.Cm21 | SER 272 | 7.28x27 | VdWContact |
| SER 13 | NTc.Cm20 | THR 16 | - | HBDonor |
| SER 13 | NTc.Cm20 | THR 16 | - | VdWContact |
| ILE 19 | NTc.Cm14 | TYR 14 | - | Hydrophobic |
| ILE 19 | NTc.Cm14 | TYR 14 | - | VdWContact |
| PRO 20 | NTc.Cm13 | TYR 14 | - | VdWContact |
| ARG 28 | NTc.Cm5 | GLU 172 | - | Cationic |
| ARG 28 | NTc.Cm5 | GLU 172 | - | HBDonor |
| ARG 28 | NTc.Cm5 | GLU 172 | - | VdWContact |
| THR 30 | NTc.Cm3 | HIS 181 | - | HBAcceptor |
| THR 30 | NTc.Cm3 | HIS 181 | - | VdWContact |
| SER 31 | NTc.Cm2 | SER 179 | 45.51x51 | HBDonor |
| SER 31 | NTc.Cm2 | SER 179 | 45.51x51 | VdWContact |
| SER 31 | NTc.Cm2 | HIS 181 | - | VdWContact |
| SER 32 | NTc.Cm1 | SER 180 | 45.52x52 | HBDonor |
| SER 32 | NTc.Cm1 | SER 180 | 45.52x52 | VdWContact |
| SER 32 | NTc.Cm1 | HIS 181 | - | VdWContact |
| SER 32 | NTc.Cm1 | PHE 182 | - | HBAcceptor |
| SER 32 | NTc.Cm1 | PHE 182 | - | VdWContact |
| SER 32 | NTc.Cm1 | TYR 187 | 5.31x32 | VdWContact |
| CYS 34 | CX.5 | TYR 187 | 5.31x32 | HBAcceptor |
| CYS 34 | CX.5 | TYR 187 | 5.31x32 | VdWContact |
| CYS 34 | CX.5 | LYS 191 | 5.35x36 | VdWContact |
| SER 35 | cxb1.1 | LYS 191 | 5.35x36 | HBAcceptor |
| SER 35 | cxb1.1 | LYS 191 | 5.35x36 | VdWContact |
| SER 35 | cxb1.1 | GLN 261 | 6.61x61 | VdWContact |
| SER 35 | cxb1.1 | ASN 267 | - | HBDonor |
| SER 35 | cxb1.1 | ASN 267 | - | VdWContact |
| ASN 36 | cxb1.2 | ASN 267 | - | VdWContact |
| GLU 37 | cxb1.5 | TYR 184 | - | Hydrophobic |
| GLU 37 | cxb1.5 | TYR 184 | - | VdWContact |
| GLU 37 | cxb1.5 | TYR 187 | 5.31x32 | Hydrophobic |
| GLU 37 | cxb1.5 | TYR 187 | 5.31x32 | VdWContact |
| ILE 40 | cxb1.8 | PRO 19 | - | Hydrophobic |
| ARG 45 | cxb1.16 | ILE 9 | - | VdWContact |
| ARG 45 | cxb1.16 | ASP 11 | - | Cationic |
| ARG 45 | cxb1.16 | ASP 11 | - | HBDonor |
| ARG 45 | cxb1.16 | ASP 11 | - | VdWContact |
| LYS 47 | B1.2 | ASP 11 | - | Cationic |
| LYS 47 | B1.2 | TYR 15 | - | HBDonor |
| LYS 47 | B1.2 | TYR 15 | - | Hydrophobic |
| LYS 47 | B1.2 | TYR 15 | - | VdWContact |
| GLU 48 | B1.3 | GLU 18 | - | VdWContact |
| GLU 48 | B1.3 | PRO 19 | - | Hydrophobic |
| GLU 48 | B1.3 | PRO 19 | - | VdWContact |
| CYS 50 | B1.5 | SER 17 | - | HBDonor |
| CYS 50 | B1.5 | SER 17 | - | VdWContact |
| CYS 50 | B1.5 | PRO 19 | - | VdWContact |
| ASP 53 | b1b2.4 | TYR 184 | - | Hydrophobic |
| ASP 53 | b1b2.4 | TYR 184 | - | VdWContact |
| ARG 62 | B2.2 | TYR 184 | - | CationPi |
| SER 70 | b2b3.12 | LYS 171 | - | VdWContact |
| ARG 72 | B3.2 | ASP 95 | 23.51x51 | Cationic |
| ARG 72 | B3.2 | ASP 95 | 23.51x51 | HBDonor |
| ARG 72 | B3.2 | ASP 95 | 23.51x51 | VdWContact |
| ARG 72 | B3.2 | TYR 176 | - | Hydrophobic |
