Predicted complex interactions
CCL13_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL13_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 134
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 4 | NTc.Cm30 | HIS 175 | - | Hydrophobic |
| GLN 4 | NTc.Cm30 | HIS 175 | - | VdWContact |
| GLY 5 | NTc.Cm29 | HIS 175 | - | VdWContact |
| LEU 6 | NTc.Cm28 | ALA 91 | 2.65x65 | VdWContact |
| LEU 6 | NTc.Cm28 | ALA 92 | 2.66x66 | Hydrophobic |
| LEU 6 | NTc.Cm28 | ALA 92 | 2.66x66 | VdWContact |
| ALA 7 | NTc.Cm27 | TYR 89 | 2.63x63 | VdWContact |
| ALA 7 | NTc.Cm27 | ALA 92 | 2.66x66 | VdWContact |
| ALA 7 | NTc.Cm27 | GLN 93 | 23.49x49 | Hydrophobic |
| ALA 7 | NTc.Cm27 | GLN 93 | 23.49x49 | VdWContact |
| ALA 7 | NTc.Cm27 | HIS 175 | - | Hydrophobic |
| ALA 7 | NTc.Cm27 | HIS 175 | - | VdWContact |
| ALA 7 | NTc.Cm27 | TYR 176 | - | VdWContact |
| ALA 7 | NTc.Cm27 | THR 177 | - | Hydrophobic |
| ALA 7 | NTc.Cm27 | THR 177 | - | VdWContact |
| GLN 8 | NTc.Cm26 | LYS 26 | 1.28x28 | Hydrophobic |
| GLN 8 | NTc.Cm26 | LYS 26 | 1.28x28 | VdWContact |
| GLN 8 | NTc.Cm26 | ALA 29 | 1.31x31 | VdWContact |
| GLN 8 | NTc.Cm26 | ALA 30 | 1.32x32 | VdWContact |
| GLN 8 | NTc.Cm26 | TYR 89 | 2.63x63 | HBAcceptor |
| GLN 8 | NTc.Cm26 | TYR 89 | 2.63x63 | VdWContact |
| GLN 8 | NTc.Cm26 | ALA 90 | 2.64x64 | HBDonor |
| GLN 8 | NTc.Cm26 | ALA 90 | 2.64x64 | VdWContact |
| GLN 8 | NTc.Cm26 | GLN 280 | 7.36x35 | HBAcceptor |
| PRO 9 | NTc.Cm25 | TRP 86 | 2.60x60 | Hydrophobic |
| PRO 9 | NTc.Cm25 | TYR 89 | 2.63x63 | Hydrophobic |
| PRO 9 | NTc.Cm25 | TYR 89 | 2.63x63 | VdWContact |
| PRO 9 | NTc.Cm25 | ALA 90 | 2.64x64 | Hydrophobic |
| PRO 9 | NTc.Cm25 | ALA 90 | 2.64x64 | VdWContact |
| ASP 10 | NTc.Cm24 | THR 177 | - | VdWContact |
| ASP 10 | NTc.Cm24 | CYS 178 | 45.50x50 | HBAcceptor |
| ASP 10 | NTc.Cm24 | CYS 178 | 45.50x50 | HBDonor |
| ASP 10 | NTc.Cm24 | CYS 178 | 45.50x50 | VdWContact |
| ASP 10 | NTc.Cm24 | SER 179 | 45.51x51 | HBAcceptor |
| ASP 10 | NTc.Cm24 | SER 179 | 45.51x51 | VdWContact |
| ALA 11 | NTc.Cm23 | GLU 283 | 7.39x38 | VdWContact |
| LEU 12 | NTc.Cm22 | TYR 37 | 1.39x39 | Hydrophobic |
| LEU 12 | NTc.Cm22 | TYR 37 | 1.39x39 | VdWContact |
| LEU 12 | NTc.Cm22 | TRP 86 | 2.60x60 | Hydrophobic |
| LEU 12 | NTc.Cm22 | TRP 86 | 2.60x60 | VdWContact |
| LEU 12 | NTc.Cm22 | GLN 280 | 7.36x35 | HBAcceptor |
| LEU 12 | NTc.Cm22 | GLN 280 | 7.36x35 | VdWContact |
| LEU 12 | NTc.Cm22 | GLU 283 | 7.39x38 | Hydrophobic |
| LEU 12 | NTc.Cm22 | GLU 283 | 7.39x38 | VdWContact |
| LEU 12 | NTc.Cm22 | MET 287 | 7.43x42 | Hydrophobic |
| ASN 13 | NTc.Cm21 | LYS 26 | 1.28x28 | VdWContact |
| VAL 14 | NTc.Cm20 | LYS 22 | 1.24x24 | Hydrophobic |
| VAL 14 | NTc.Cm20 | LYS 22 | 1.24x24 | VdWContact |
| VAL 14 | NTc.Cm20 | VAL 25 | 1.27x27 | Hydrophobic |
| VAL 14 | NTc.Cm20 | VAL 25 | 1.27x27 | VdWContact |
| VAL 14 | NTc.Cm20 | LYS 26 | 1.28x28 | VdWContact |
| VAL 14 | NTc.Cm20 | ASP 276 | 7.32x31 | Hydrophobic |
| VAL 14 | NTc.Cm20 | ASP 276 | 7.32x31 | VdWContact |
| VAL 14 | NTc.Cm20 | GLN 280 | 7.36x35 | Hydrophobic |
| VAL 14 | NTc.Cm20 | GLN 280 | 7.36x35 | VdWContact |
| PRO 15 | NTc.Cm19 | LYS 22 | 1.24x24 | Hydrophobic |
| PRO 15 | NTc.Cm19 | LYS 22 | 1.24x24 | VdWContact |
| SER 16 | NTc.Cm18 | LYS 22 | 1.24x24 | HBAcceptor |
| SER 16 | NTc.Cm18 | LYS 22 | 1.24x24 | VdWContact |
| SER 16 | NTc.Cm18 | LYS 26 | 1.28x28 | VdWContact |
| SER 16 | NTc.Cm18 | GLU 172 | - | HBDonor |
| SER 16 | NTc.Cm18 | GLU 172 | - | VdWContact |
| THR 17 | NTc.Cm17 | PRO 19 | - | Hydrophobic |
| THR 17 | NTc.Cm17 | PRO 19 | - | VdWContact |
| THR 17 | NTc.Cm17 | CYS 20 | - | VdWContact |
| CYS 18 | NTc.Cm16 | CYS 20 | - | HBAcceptor |
| CYS 18 | NTc.Cm16 | CYS 20 | - | HBDonor |
| CYS 18 | NTc.Cm16 | CYS 20 | - | VdWContact |
| CYS 18 | NTc.Cm16 | LYS 22 | 1.24x24 | VdWContact |
| PHE 20 | NTc.Cm14 | CYS 20 | - | Hydrophobic |
| PHE 20 | NTc.Cm14 | CYS 20 | - | VdWContact |
| PHE 20 | NTc.Cm14 | ASN 267 | - | VdWContact |
| PHE 20 | NTc.Cm14 | CYS 269 | 7.25x24 | Hydrophobic |
| PHE 20 | NTc.Cm14 | SER 272 | 7.28x27 | VdWContact |
| THR 21 | NTc.Cm13 | SER 17 | - | HBAcceptor |
| THR 21 | NTc.Cm13 | SER 17 | - | VdWContact |
| SER 23 | NTc.Cm11 | THR 16 | - | VdWContact |
| SER 23 | NTc.Cm11 | SER 17 | - | HBAcceptor |
| SER 23 | NTc.Cm11 | SER 17 | - | VdWContact |
| SER 24 | NTc.Cm10 | TYR 15 | - | VdWContact |
| LYS 25 | NTc.Cm9 | ASP 11 | - | Cationic |
| LYS 25 | NTc.Cm9 | TYR 15 | - | CationPi |
| LYS 25 | NTc.Cm9 | TYR 15 | - | Hydrophobic |
| LYS 25 | NTc.Cm9 | TYR 15 | - | VdWContact |
| ILE 27 | NTc.Cm7 | THR 16 | - | Hydrophobic |
| ARG 31 | NTc.Cm3 | ILE 12 | - | VdWContact |
| VAL 36 | cxb1.1 | GLU 172 | - | Hydrophobic |
| VAL 36 | cxb1.1 | GLU 172 | - | VdWContact |
| ILE 37 | cxb1.2 | GLN 170 | - | HBAcceptor |
| ILE 37 | cxb1.2 | GLN 170 | - | VdWContact |
| ILE 37 | cxb1.2 | HIS 181 | - | VdWContact |
| THR 38 | cxb1.5 | HIS 181 | - | HBAcceptor |
| THR 38 | cxb1.5 | HIS 181 | - | VdWContact |
| THR 39 | cxb1.6 | SER 179 | 45.51x51 | VdWContact |
| SER 40 | cxb1.7 | SER 180 | 45.52x52 | HBDonor |
| SER 40 | cxb1.7 | SER 180 | 45.52x52 | VdWContact |
| SER 40 | cxb1.7 | PHE 182 | - | HBAcceptor |
| SER 40 | cxb1.7 | PHE 182 | - | VdWContact |
| SER 40 | cxb1.7 | TYR 187 | 5.31x32 | VdWContact |
| ARG 41 | cxb1.8 | GLU 283 | 7.39x38 | Cationic |
| ARG 41 | cxb1.8 | GLU 283 | 7.39x38 | HBDonor |
| ARG 41 | cxb1.8 | GLU 283 | 7.39x38 | VdWContact |
| CYS 42 | cxb1.10 | TYR 187 | 5.31x32 | HBAcceptor |
| CYS 42 | cxb1.10 | TYR 187 | 5.31x32 | VdWContact |
| CYS 42 | cxb1.10 | LYS 191 | 5.35x36 | HBAcceptor |
| CYS 42 | cxb1.10 | LYS 191 | 5.35x36 | VdWContact |
| PRO 43 | cxb1.11 | TYR 187 | 5.31x32 | VdWContact |
| PRO 43 | cxb1.11 | LYS 191 | 5.35x36 | HBAcceptor |
| PRO 43 | cxb1.11 | LYS 191 | 5.35x36 | VdWContact |
| PRO 43 | cxb1.11 | GLN 261 | 6.61x61 | VdWContact |
| LYS 45 | cxb1.15 | PHE 182 | - | HBDonor |
| LYS 45 | cxb1.15 | PHE 182 | - | VdWContact |
| LYS 45 | cxb1.15 | TYR 184 | - | HBDonor |
| LYS 45 | cxb1.15 | TYR 184 | - | Hydrophobic |
| LYS 45 | cxb1.15 | TYR 184 | - | VdWContact |
| LYS 45 | cxb1.15 | TYR 187 | 5.31x32 | Hydrophobic |
| LYS 45 | cxb1.15 | TYR 187 | 5.31x32 | VdWContact |
| ILE 48 | B1.2 | PRO 19 | - | Hydrophobic |
| LYS 55 | b1b2.6 | ASN 13 | - | HBDonor |
| LYS 55 | b1b2.6 | ASN 13 | - | VdWContact |
| LYS 55 | b1b2.6 | THR 16 | - | HBDonor |
| LYS 55 | b1b2.6 | THR 16 | - | VdWContact |
| LYS 55 | b1b2.6 | GLU 18 | - | Cationic |
| LYS 55 | b1b2.6 | GLU 18 | - | HBDonor |
| LYS 55 | b1b2.6 | GLU 18 | - | VdWContact |
| GLU 56 | b1b2.9 | PRO 19 | - | Hydrophobic |
| GLU 56 | b1b2.9 | GLN 21 | - | HBAcceptor |
| GLU 56 | b1b2.9 | GLN 21 | - | VdWContact |
| ILE 57 | b1b2.10 | THR 16 | - | Hydrophobic |
| CYS 58 | b1b2.12 | SER 17 | - | HBDonor |
| CYS 58 | b1b2.12 | SER 17 | - | VdWContact |
| CYS 58 | b1b2.12 | PRO 19 | - | VdWContact |
| PRO 61 | b1b2.16 | TYR 184 | - | Hydrophobic |
| LYS 62 | B2.1 | TYR 184 | - | Hydrophobic |
