Predicted complex interactions
CCL14_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL14_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 111
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 3 | NTc.Cm32 | HIS 175 | - | Hydrophobic |
| THR 3 | NTc.Cm32 | HIS 175 | - | VdWContact |
| GLU 4 | NTc.Cm31 | GLN 27 | 1.29x29 | HBAcceptor |
| GLU 4 | NTc.Cm31 | GLN 27 | 1.29x29 | VdWContact |
| SER 5 | NTc.Cm30 | ALA 91 | 2.65x65 | VdWContact |
| SER 5 | NTc.Cm30 | ALA 92 | 2.66x66 | VdWContact |
| SER 6 | NTc.Cm29 | LYS 26 | 1.28x28 | VdWContact |
| SER 6 | NTc.Cm29 | ALA 91 | 2.65x65 | VdWContact |
| SER 6 | NTc.Cm29 | ALA 92 | 2.66x66 | VdWContact |
| SER 7 | NTc.Cm28 | LYS 26 | 1.28x28 | VdWContact |
| SER 7 | NTc.Cm28 | ALA 29 | 1.31x31 | VdWContact |
| SER 7 | NTc.Cm28 | ALA 30 | 1.32x32 | VdWContact |
| SER 7 | NTc.Cm28 | PRO 34 | 1.36x36 | VdWContact |
| SER 7 | NTc.Cm28 | ALA 90 | 2.64x64 | HBDonor |
| SER 7 | NTc.Cm28 | ALA 90 | 2.64x64 | VdWContact |
| ARG 8 | NTc.Cm27 | LYS 26 | 1.28x28 | VdWContact |
| ARG 8 | NTc.Cm27 | TYR 89 | 2.63x63 | Hydrophobic |
| ARG 8 | NTc.Cm27 | TYR 89 | 2.63x63 | VdWContact |
| ARG 8 | NTc.Cm27 | ALA 90 | 2.64x64 | VdWContact |
| ARG 8 | NTc.Cm27 | GLU 172 | - | Cationic |
| GLY 9 | NTc.Cm26 | LEU 33 | 1.35x35 | VdWContact |
| GLY 9 | NTc.Cm26 | TRP 86 | 2.60x60 | VdWContact |
| GLY 9 | NTc.Cm26 | ALA 90 | 2.64x64 | VdWContact |
| PRO 10 | NTc.Cm25 | TYR 37 | 1.39x39 | Hydrophobic |
| PRO 10 | NTc.Cm25 | TYR 37 | 1.39x39 | VdWContact |
| PRO 10 | NTc.Cm25 | TRP 86 | 2.60x60 | Hydrophobic |
| PRO 10 | NTc.Cm25 | TRP 86 | 2.60x60 | VdWContact |
| PRO 10 | NTc.Cm25 | GLU 283 | 7.39x38 | VdWContact |
| PRO 10 | NTc.Cm25 | MET 287 | 7.43x42 | Hydrophobic |
| PRO 10 | NTc.Cm25 | MET 287 | 7.43x42 | VdWContact |
| TYR 11 | NTc.Cm24 | ASP 276 | 7.32x31 | Hydrophobic |
| TYR 11 | NTc.Cm24 | ASP 276 | 7.32x31 | VdWContact |
| TYR 11 | NTc.Cm24 | MET 279 | 7.35x34 | Hydrophobic |
| TYR 11 | NTc.Cm24 | MET 279 | 7.35x34 | VdWContact |
| TYR 11 | NTc.Cm24 | GLN 280 | 7.36x35 | HBAcceptor |
| TYR 11 | NTc.Cm24 | GLN 280 | 7.36x35 | Hydrophobic |
| TYR 11 | NTc.Cm24 | GLN 280 | 7.36x35 | VdWContact |
| TYR 11 | NTc.Cm24 | GLU 283 | 7.39x38 | HBDonor |
| TYR 11 | NTc.Cm24 | GLU 283 | 7.39x38 | VdWContact |
| HIS 12 | NTc.Cm23 | TRP 86 | 2.60x60 | Hydrophobic |
| HIS 12 | NTc.Cm23 | TYR 89 | 2.63x63 | Hydrophobic |
| HIS 12 | NTc.Cm23 | TYR 89 | 2.63x63 | PiStacking |
| HIS 12 | NTc.Cm23 | TYR 89 | 2.63x63 | VdWContact |
| PRO 13 | NTc.Cm22 | LYS 22 | 1.24x24 | Hydrophobic |
| PRO 13 | NTc.Cm22 | VAL 25 | 1.27x27 | Hydrophobic |
| PRO 13 | NTc.Cm22 | VAL 25 | 1.27x27 | VdWContact |
| PRO 13 | NTc.Cm22 | LYS 26 | 1.28x28 | Hydrophobic |
| PRO 13 | NTc.Cm22 | LYS 26 | 1.28x28 | VdWContact |
| PRO 13 | NTc.Cm22 | ASP 276 | 7.32x31 | Hydrophobic |
| PRO 13 | NTc.Cm22 | ASP 276 | 7.32x31 | VdWContact |
| PRO 13 | NTc.Cm22 | GLN 280 | 7.36x35 | VdWContact |
| SER 14 | NTc.Cm21 | LYS 22 | 1.24x24 | VdWContact |
| GLU 15 | NTc.Cm20 | PRO 19 | - | Hydrophobic |
| GLU 15 | NTc.Cm20 | PRO 19 | - | VdWContact |
| GLU 15 | NTc.Cm20 | CYS 20 | - | VdWContact |
| CYS 16 | NTc.Cm19 | CYS 20 | - | HBAcceptor |
| CYS 16 | NTc.Cm19 | CYS 20 | - | VdWContact |
| CYS 16 | NTc.Cm19 | LYS 22 | 1.24x24 | Anionic |
| PHE 18 | NTc.Cm17 | CYS 20 | - | Hydrophobic |
| PHE 18 | NTc.Cm17 | CYS 20 | - | VdWContact |
| PHE 18 | NTc.Cm17 | CYS 269 | 7.25x24 | Hydrophobic |
| PHE 18 | NTc.Cm17 | CYS 269 | 7.25x24 | VdWContact |
| PHE 18 | NTc.Cm17 | SER 272 | 7.28x27 | VdWContact |
| THR 19 | NTc.Cm16 | SER 17 | - | VdWContact |
| TYR 23 | NTc.Cm12 | ILE 12 | - | Hydrophobic |
| ILE 25 | NTc.Cm10 | TYR 14 | - | Hydrophobic |
| ILE 25 | NTc.Cm10 | TYR 14 | - | VdWContact |
| ARG 29 | NTc.Cm6 | ILE 9 | - | VdWContact |
| ARG 29 | NTc.Cm6 | TYR 14 | - | HBDonor |
| ARG 29 | NTc.Cm6 | TYR 14 | - | VdWContact |
| TYR 34 | NTc.Cm1 | GLU 172 | - | Hydrophobic |
| GLU 35 | CX.1 | ARG 168 | - | Anionic |
| GLU 35 | CX.1 | ARG 168 | - | HBAcceptor |
| GLU 35 | CX.1 | ARG 168 | - | VdWContact |
| GLU 35 | CX.1 | GLN 170 | - | HBAcceptor |
| GLU 35 | CX.1 | GLN 170 | - | VdWContact |
| GLU 35 | CX.1 | HIS 181 | - | Hydrophobic |
| GLU 35 | CX.1 | HIS 181 | - | VdWContact |
| THR 36 | CX.5 | HIS 181 | - | HBAcceptor |
| THR 36 | CX.5 | HIS 181 | - | VdWContact |
| SER 38 | cxb1.2 | SER 180 | 45.52x52 | HBDonor |
| SER 38 | cxb1.2 | SER 180 | 45.52x52 | VdWContact |
| SER 38 | cxb1.2 | HIS 181 | - | HBDonor |
| SER 38 | cxb1.2 | HIS 181 | - | VdWContact |
| SER 38 | cxb1.2 | PHE 182 | - | HBAcceptor |
| SER 38 | cxb1.2 | PHE 182 | - | VdWContact |
| SER 38 | cxb1.2 | TYR 187 | 5.31x32 | VdWContact |
| GLN 39 | cxb1.5 | ASN 258 | 6.58x58 | HBAcceptor |
| GLN 39 | cxb1.5 | ASN 258 | 6.58x58 | VdWContact |
| CYS 40 | cxb1.6 | TYR 187 | 5.31x32 | HBAcceptor |
| CYS 40 | cxb1.6 | TYR 187 | 5.31x32 | VdWContact |
| CYS 40 | cxb1.6 | LYS 191 | 5.35x36 | HBAcceptor |
| CYS 40 | cxb1.6 | LYS 191 | 5.35x36 | VdWContact |
| SER 41 | cxb1.7 | LYS 191 | 5.35x36 | VdWContact |
| SER 41 | cxb1.7 | GLN 261 | 6.61x61 | VdWContact |
| LYS 42 | cxb1.8 | GLU 262 | 6.62x62 | Cationic |
| LYS 42 | cxb1.8 | GLU 262 | 6.62x62 | VdWContact |
| PRO 43 | cxb1.10 | TYR 184 | - | Hydrophobic |
| PRO 43 | cxb1.10 | TYR 187 | 5.31x32 | Hydrophobic |
| PRO 43 | cxb1.10 | TYR 187 | 5.31x32 | VdWContact |
| VAL 46 | cxb1.15 | PRO 19 | - | Hydrophobic |
| ILE 48 | B1.1 | GLY 173 | - | VdWContact |
| ARG 51 | B1.4 | ASP 11 | - | Cationic |
| HIS 53 | B1.6 | TYR 15 | - | Hydrophobic |
| SER 54 | B1.7 | GLU 18 | - | VdWContact |
| VAL 55 | b1b2.4 | TYR 14 | - | Hydrophobic |
| VAL 55 | b1b2.4 | TYR 14 | - | VdWContact |
| VAL 55 | b1b2.4 | SER 17 | - | VdWContact |
| CYS 56 | b1b2.6 | SER 17 | - | HBDonor |
| CYS 56 | b1b2.6 | SER 17 | - | VdWContact |
| PRO 59 | b1b2.12 | TYR 184 | - | Hydrophobic |
