Predicted complex interactions
CCL15_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL15_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 132
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 21 | NTc.Cm32 | HIS 175 | - | Hydrophobic |
| VAL 21 | NTc.Cm32 | HIS 175 | - | VdWContact |
| VAL 22 | NTc.Cm31 | ALA 30 | 1.32x32 | Hydrophobic |
| VAL 22 | NTc.Cm31 | ALA 30 | 1.32x32 | VdWContact |
| VAL 22 | NTc.Cm31 | ALA 90 | 2.64x64 | VdWContact |
| VAL 22 | NTc.Cm31 | ALA 91 | 2.65x65 | VdWContact |
| LEU 23 | NTc.Cm30 | TYR 89 | 2.63x63 | Hydrophobic |
| LEU 23 | NTc.Cm30 | TYR 89 | 2.63x63 | VdWContact |
| LEU 23 | NTc.Cm30 | ALA 92 | 2.66x66 | HBDonor |
| LEU 23 | NTc.Cm30 | ALA 92 | 2.66x66 | VdWContact |
| LEU 23 | NTc.Cm30 | GLN 93 | 23.49x49 | Hydrophobic |
| LEU 23 | NTc.Cm30 | GLN 93 | 23.49x49 | VdWContact |
| LEU 23 | NTc.Cm30 | HIS 175 | - | Hydrophobic |
| LEU 23 | NTc.Cm30 | HIS 175 | - | VdWContact |
| LEU 23 | NTc.Cm30 | TYR 176 | - | VdWContact |
| LEU 23 | NTc.Cm30 | THR 177 | - | Hydrophobic |
| ASN 24 | NTc.Cm29 | LYS 26 | 1.28x28 | VdWContact |
| ASN 24 | NTc.Cm29 | ALA 29 | 1.31x31 | Hydrophobic |
| ASN 24 | NTc.Cm29 | TYR 89 | 2.63x63 | VdWContact |
| ASN 24 | NTc.Cm29 | ALA 90 | 2.64x64 | VdWContact |
| SER 25 | NTc.Cm28 | TRP 86 | 2.60x60 | HBDonor |
| SER 25 | NTc.Cm28 | TRP 86 | 2.60x60 | VdWContact |
| SER 25 | NTc.Cm28 | TYR 89 | 2.63x63 | VdWContact |
| SER 25 | NTc.Cm28 | ALA 90 | 2.64x64 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 37 | 1.39x39 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 37 | 1.39x39 | VdWContact |
| PHE 26 | NTc.Cm27 | TRP 86 | 2.60x60 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TRP 86 | 2.60x60 | PiStacking |
| PHE 26 | NTc.Cm27 | TRP 86 | 2.60x60 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 108 | 3.32x32 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 108 | 3.32x32 | VdWContact |
| PHE 26 | NTc.Cm27 | GLU 283 | 7.39x38 | Hydrophobic |
| PHE 26 | NTc.Cm27 | GLU 283 | 7.39x38 | VdWContact |
| PHE 26 | NTc.Cm27 | MET 287 | 7.43x42 | Hydrophobic |
| PHE 26 | NTc.Cm27 | MET 287 | 7.43x42 | VdWContact |
| HIS 27 | NTc.Cm26 | ASP 276 | 7.32x31 | Hydrophobic |
| HIS 27 | NTc.Cm26 | ASP 276 | 7.32x31 | VdWContact |
| HIS 27 | NTc.Cm26 | MET 279 | 7.35x34 | Hydrophobic |
| HIS 27 | NTc.Cm26 | MET 279 | 7.35x34 | VdWContact |
| HIS 27 | NTc.Cm26 | GLN 280 | 7.36x35 | HBAcceptor |
| HIS 27 | NTc.Cm26 | GLN 280 | 7.36x35 | Hydrophobic |
| HIS 27 | NTc.Cm26 | GLN 280 | 7.36x35 | VdWContact |
| HIS 27 | NTc.Cm26 | GLU 283 | 7.39x38 | VdWContact |
| PHE 28 | NTc.Cm25 | LYS 26 | 1.28x28 | Hydrophobic |
| PHE 28 | NTc.Cm25 | LYS 26 | 1.28x28 | VdWContact |
| PHE 28 | NTc.Cm25 | THR 177 | - | Hydrophobic |
| ALA 29 | NTc.Cm24 | LYS 22 | 1.24x24 | Hydrophobic |
| ALA 29 | NTc.Cm24 | LYS 22 | 1.24x24 | VdWContact |
| ALA 29 | NTc.Cm24 | VAL 25 | 1.27x27 | Hydrophobic |
| ALA 29 | NTc.Cm24 | VAL 25 | 1.27x27 | VdWContact |
| ALA 29 | NTc.Cm24 | LYS 26 | 1.28x28 | Hydrophobic |
| ALA 29 | NTc.Cm24 | LYS 26 | 1.28x28 | VdWContact |
| ALA 29 | NTc.Cm24 | ASP 276 | 7.32x31 | Hydrophobic |
| ALA 29 | NTc.Cm24 | ASP 276 | 7.32x31 | VdWContact |
| ALA 30 | NTc.Cm23 | LYS 22 | 1.24x24 | HBAcceptor |
| ALA 30 | NTc.Cm23 | LYS 22 | 1.24x24 | VdWContact |
| ASP 31 | NTc.Cm22 | CYS 20 | - | VdWContact |
| ASP 31 | NTc.Cm22 | GLN 21 | - | VdWContact |
| ASP 31 | NTc.Cm22 | LYS 22 | 1.24x24 | HBAcceptor |
| ASP 31 | NTc.Cm22 | LYS 22 | 1.24x24 | VdWContact |
| ASP 31 | NTc.Cm22 | LYS 26 | 1.28x28 | Anionic |
| ASP 31 | NTc.Cm22 | LYS 26 | 1.28x28 | HBAcceptor |
| ASP 31 | NTc.Cm22 | LYS 26 | 1.28x28 | VdWContact |
| CYS 32 | NTc.Cm21 | CYS 20 | - | HBAcceptor |
| CYS 32 | NTc.Cm21 | CYS 20 | - | HBDonor |
| CYS 32 | NTc.Cm21 | CYS 20 | - | VdWContact |
| CYS 32 | NTc.Cm21 | LYS 22 | 1.24x24 | Anionic |
| THR 34 | NTc.Cm19 | CYS 20 | - | Hydrophobic |
| THR 34 | NTc.Cm19 | CYS 269 | 7.25x24 | Hydrophobic |
| SER 35 | NTc.Cm18 | THR 16 | - | VdWContact |
| SER 35 | NTc.Cm18 | SER 17 | - | VdWContact |
| ILE 37 | NTc.Cm16 | ILE 12 | - | Hydrophobic |
| PRO 42 | NTc.Cm11 | ILE 12 | - | Hydrophobic |
| PRO 42 | NTc.Cm11 | ILE 12 | - | VdWContact |
| PRO 42 | NTc.Cm11 | TYR 14 | - | Hydrophobic |
| PRO 42 | NTc.Cm11 | TYR 14 | - | VdWContact |
| MET 46 | NTc.Cm7 | TYR 14 | - | Hydrophobic |
| PHE 50 | NTc.Cm3 | GLU 172 | - | Hydrophobic |
| PHE 50 | NTc.Cm3 | GLU 172 | - | VdWContact |
| GLU 51 | NTc.Cm2 | ARG 168 | - | Anionic |
| GLU 51 | NTc.Cm2 | ARG 168 | - | HBAcceptor |
| GLU 51 | NTc.Cm2 | ARG 168 | - | VdWContact |
| GLU 51 | NTc.Cm2 | GLN 170 | - | HBAcceptor |
| GLU 51 | NTc.Cm2 | GLN 170 | - | VdWContact |
| GLU 51 | NTc.Cm2 | HIS 181 | - | VdWContact |
| THR 52 | NTc.Cm1 | HIS 181 | - | HBAcceptor |
| THR 52 | NTc.Cm1 | HIS 181 | - | VdWContact |
| SER 53 | CX.1 | SER 179 | 45.51x51 | HBDonor |
| SER 53 | CX.1 | SER 179 | 45.51x51 | VdWContact |
| SER 54 | CX.5 | SER 180 | 45.52x52 | HBDonor |
| SER 54 | CX.5 | SER 180 | 45.52x52 | VdWContact |
| SER 54 | CX.5 | HIS 181 | - | HBDonor |
| SER 54 | CX.5 | HIS 181 | - | VdWContact |
| SER 54 | CX.5 | PHE 182 | - | HBAcceptor |
| SER 54 | CX.5 | PHE 182 | - | VdWContact |
| SER 54 | CX.5 | TYR 187 | 5.31x32 | VdWContact |
| SER 54 | CX.5 | LYS 191 | 5.35x36 | HBAcceptor |
| SER 54 | CX.5 | LYS 191 | 5.35x36 | VdWContact |
| GLU 55 | cxb1.1 | LYS 191 | 5.35x36 | HBAcceptor |
| GLU 55 | cxb1.1 | LYS 191 | 5.35x36 | VdWContact |
| CYS 56 | cxb1.2 | TYR 187 | 5.31x32 | HBAcceptor |
| CYS 56 | cxb1.2 | TYR 187 | 5.31x32 | VdWContact |
| CYS 56 | cxb1.2 | LYS 191 | 5.35x36 | HBAcceptor |
| CYS 56 | cxb1.2 | LYS 191 | 5.35x36 | VdWContact |
| SER 57 | cxb1.5 | GLN 261 | 6.61x61 | VdWContact |
| LYS 58 | cxb1.6 | GLU 262 | 6.62x62 | Cationic |
| LYS 58 | cxb1.6 | GLU 262 | 6.62x62 | VdWContact |
| PRO 59 | cxb1.7 | TYR 184 | - | Hydrophobic |
| PRO 59 | cxb1.7 | TYR 187 | 5.31x32 | Hydrophobic |
| PRO 59 | cxb1.7 | TYR 187 | 5.31x32 | VdWContact |
| ILE 62 | cxb1.11 | PRO 19 | - | Hydrophobic |
| THR 65 | cxb1.16 | TYR 14 | - | Hydrophobic |
| ARG 69 | B1.4 | TYR 15 | - | HBDonor |
| ARG 69 | B1.4 | TYR 15 | - | VdWContact |
| GLN 70 | B1.5 | PRO 19 | - | Hydrophobic |
| GLN 70 | B1.5 | PRO 19 | - | VdWContact |
| GLN 70 | B1.5 | GLN 21 | - | VdWContact |
| VAL 71 | B1.6 | TYR 14 | - | Hydrophobic |
| VAL 71 | B1.6 | TYR 14 | - | VdWContact |
| VAL 71 | B1.6 | SER 17 | - | VdWContact |
| CYS 72 | B1.7 | SER 17 | - | HBDonor |
| CYS 72 | B1.7 | SER 17 | - | VdWContact |
| CYS 72 | B1.7 | PRO 19 | - | VdWContact |
| PRO 75 | b1b2.9 | TYR 184 | - | Hydrophobic |
| TYR 90 | b2b3.12 | LYS 171 | - | Hydrophobic |
| TYR 90 | b2b3.12 | LYS 171 | - | VdWContact |
| TYR 90 | b2b3.12 | GLY 173 | - | VdWContact |
| SER 91 | B3.1 | LYS 171 | - | HBAcceptor |
| SER 91 | B3.1 | LYS 171 | - | VdWContact |
| ILE 92 | B3.2 | LYS 171 | - | Anionic |
| ILE 92 | B3.2 | TYR 176 | - | Hydrophobic |
| ILE 92 | B3.2 | TYR 176 | - | VdWContact |
