Predicted complex interactions
CCL16_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL16_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 116
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm36 | ARG 168 | - | Anionic |
| GLN 1 | NTc.Cm36 | ARG 168 | - | HBAcceptor |
| GLN 1 | NTc.Cm36 | ARG 168 | - | VdWContact |
| GLN 1 | NTc.Cm36 | GLN 170 | - | VdWContact |
| GLN 1 | NTc.Cm36 | HIS 181 | - | VdWContact |
| PRO 2 | NTc.Cm35 | SER 180 | 45.52x52 | HBAcceptor |
| PRO 2 | NTc.Cm35 | SER 180 | 45.52x52 | VdWContact |
| PRO 2 | NTc.Cm35 | PHE 182 | - | Hydrophobic |
| PRO 2 | NTc.Cm35 | PHE 182 | - | VdWContact |
| LYS 3 | NTc.Cm34 | SER 179 | 45.51x51 | VdWContact |
| VAL 4 | NTc.Cm33 | TRP 86 | 2.60x60 | Hydrophobic |
| VAL 4 | NTc.Cm33 | THR 105 | 3.29x29 | Hydrophobic |
| VAL 4 | NTc.Cm33 | THR 105 | 3.29x29 | VdWContact |
| VAL 4 | NTc.Cm33 | THR 167 | 4.64x65 | Hydrophobic |
| PRO 5 | NTc.Cm32 | TRP 86 | 2.60x60 | Hydrophobic |
| PRO 5 | NTc.Cm32 | TRP 86 | 2.60x60 | VdWContact |
| PRO 5 | NTc.Cm32 | TYR 108 | 3.32x32 | Hydrophobic |
| PRO 5 | NTc.Cm32 | GLU 283 | 7.39x38 | Hydrophobic |
| PRO 5 | NTc.Cm32 | GLU 283 | 7.39x38 | VdWContact |
| PRO 5 | NTc.Cm32 | MET 287 | 7.43x42 | Hydrophobic |
| GLU 6 | NTc.Cm31 | ASN 258 | 6.58x58 | HBAcceptor |
| GLU 6 | NTc.Cm31 | GLU 283 | 7.39x38 | VdWContact |
| TRP 7 | NTc.Cm30 | ASN 258 | 6.58x58 | VdWContact |
| TRP 7 | NTc.Cm30 | ASP 276 | 7.32x31 | Hydrophobic |
| TRP 7 | NTc.Cm30 | ASP 276 | 7.32x31 | VdWContact |
| TRP 7 | NTc.Cm30 | MET 279 | 7.35x34 | Hydrophobic |
| TRP 7 | NTc.Cm30 | MET 279 | 7.35x34 | VdWContact |
| TRP 7 | NTc.Cm30 | GLN 280 | 7.36x35 | HBAcceptor |
| TRP 7 | NTc.Cm30 | GLN 280 | 7.36x35 | Hydrophobic |
| TRP 7 | NTc.Cm30 | GLN 280 | 7.36x35 | VdWContact |
| TRP 7 | NTc.Cm30 | GLU 283 | 7.39x38 | HBDonor |
| TRP 7 | NTc.Cm30 | GLU 283 | 7.39x38 | VdWContact |
| VAL 8 | NTc.Cm29 | TYR 37 | 1.39x39 | Hydrophobic |
| VAL 8 | NTc.Cm29 | TYR 37 | 1.39x39 | VdWContact |
| VAL 8 | NTc.Cm29 | TRP 86 | 2.60x60 | Hydrophobic |
| VAL 8 | NTc.Cm29 | TYR 89 | 2.63x63 | Hydrophobic |
| VAL 8 | NTc.Cm29 | ALA 90 | 2.64x64 | Hydrophobic |
| VAL 8 | NTc.Cm29 | ALA 90 | 2.64x64 | VdWContact |
| ASN 9 | NTc.Cm28 | LYS 26 | 1.28x28 | HBAcceptor |
| ASN 9 | NTc.Cm28 | LYS 26 | 1.28x28 | VdWContact |
| ASN 9 | NTc.Cm28 | TYR 89 | 2.63x63 | HBDonor |
| ASN 9 | NTc.Cm28 | TYR 89 | 2.63x63 | Hydrophobic |
| ASN 9 | NTc.Cm28 | TYR 89 | 2.63x63 | VdWContact |
| ASN 9 | NTc.Cm28 | ALA 92 | 2.66x66 | HBDonor |
| ASN 9 | NTc.Cm28 | ALA 92 | 2.66x66 | VdWContact |
| THR 10 | NTc.Cm27 | VAL 25 | 1.27x27 | Hydrophobic |
| THR 10 | NTc.Cm27 | VAL 25 | 1.27x27 | VdWContact |
| THR 10 | NTc.Cm27 | ASP 276 | 7.32x31 | Hydrophobic |
| PRO 11 | NTc.Cm26 | LYS 22 | 1.24x24 | VdWContact |
| SER 12 | NTc.Cm25 | LYS 22 | 1.24x24 | HBAcceptor |
| SER 12 | NTc.Cm25 | LYS 22 | 1.24x24 | VdWContact |
| SER 12 | NTc.Cm25 | ILE 23 | 1.25x25 | HBAcceptor |
| THR 13 | NTc.Cm24 | PRO 19 | - | Hydrophobic |
| THR 13 | NTc.Cm24 | PRO 19 | - | VdWContact |
| THR 13 | NTc.Cm24 | GLN 21 | - | VdWContact |
| CYS 14 | NTc.Cm23 | CYS 20 | - | HBAcceptor |
| CYS 14 | NTc.Cm23 | CYS 20 | - | HBDonor |
| CYS 14 | NTc.Cm23 | CYS 20 | - | VdWContact |
| CYS 14 | NTc.Cm23 | LYS 22 | 1.24x24 | Hydrophobic |
| LEU 16 | NTc.Cm21 | CYS 20 | - | Hydrophobic |
| LEU 16 | NTc.Cm21 | ASN 268 | 7.24x23 | VdWContact |
| LEU 16 | NTc.Cm21 | CYS 269 | 7.25x24 | Hydrophobic |
| LEU 16 | NTc.Cm21 | CYS 269 | 7.25x24 | VdWContact |
| LEU 16 | NTc.Cm21 | SER 272 | 7.28x27 | VdWContact |
| LYS 17 | NTc.Cm20 | ASN 267 | - | VdWContact |
| TYR 19 | NTc.Cm18 | ILE 12 | - | Hydrophobic |
| TYR 19 | NTc.Cm18 | ILE 12 | - | VdWContact |
| LEU 23 | NTc.Cm14 | ILE 12 | - | Hydrophobic |
| LEU 23 | NTc.Cm14 | TYR 14 | - | Hydrophobic |
| LEU 23 | NTc.Cm14 | TYR 14 | - | VdWContact |
| LEU 27 | NTc.Cm10 | ILE 12 | - | Hydrophobic |
| LEU 35 | NTc.Cm2 | TYR 184 | - | Hydrophobic |
| LEU 35 | NTc.Cm2 | TYR 184 | - | VdWContact |
| ASN 36 | NTc.Cm1 | GLU 172 | - | HBDonor |
| ASN 36 | NTc.Cm1 | GLU 172 | - | VdWContact |
| ASN 36 | NTc.Cm1 | THR 177 | - | VdWContact |
| ASN 36 | NTc.Cm1 | SER 179 | 45.51x51 | HBDonor |
| ASN 36 | NTc.Cm1 | SER 179 | 45.51x51 | VdWContact |
| HIS 38 | CX.5 | TYR 187 | 5.31x32 | VdWContact |
| HIS 38 | CX.5 | LYS 191 | 5.35x36 | HBAcceptor |
| HIS 38 | CX.5 | LYS 191 | 5.35x36 | PiCation |
| HIS 38 | CX.5 | LYS 191 | 5.35x36 | VdWContact |
| HIS 38 | CX.5 | ASN 258 | 6.58x58 | VdWContact |
| HIS 38 | CX.5 | GLN 261 | 6.61x61 | Hydrophobic |
| PRO 40 | cxb1.2 | TYR 184 | - | Hydrophobic |
| PRO 40 | cxb1.2 | TYR 187 | 5.31x32 | Hydrophobic |
| PRO 40 | cxb1.2 | TYR 187 | 5.31x32 | VdWContact |
| ILE 43 | cxb1.7 | PRO 19 | - | Hydrophobic |
| THR 46 | cxb1.11 | TYR 14 | - | Hydrophobic |
| ARG 48 | cxb1.15 | ASP 11 | - | Cationic |
| ARG 48 | cxb1.15 | ASP 11 | - | VdWContact |
| ARG 50 | B1.1 | ASP 11 | - | Cationic |
| ARG 50 | B1.1 | ASP 11 | - | HBDonor |
| ARG 50 | B1.1 | ASP 11 | - | VdWContact |
| ARG 50 | B1.1 | TYR 14 | - | Hydrophobic |
| ARG 50 | B1.1 | TYR 14 | - | VdWContact |
| ARG 50 | B1.1 | TYR 15 | - | HBDonor |
| ARG 50 | B1.1 | TYR 15 | - | VdWContact |
| ARG 50 | B1.1 | GLU 18 | - | Cationic |
| GLU 51 | B1.2 | GLU 18 | - | VdWContact |
| GLU 51 | B1.2 | PRO 19 | - | Hydrophobic |
| GLU 51 | B1.2 | PRO 19 | - | VdWContact |
| VAL 52 | B1.3 | TYR 14 | - | Hydrophobic |
| VAL 52 | B1.3 | TYR 14 | - | VdWContact |
| CYS 53 | B1.4 | SER 17 | - | HBDonor |
| CYS 53 | B1.4 | SER 17 | - | VdWContact |
| PRO 56 | B1.7 | TYR 184 | - | Hydrophobic |
| ASN 57 | b1b2.4 | TYR 184 | - | HBDonor |
| ASN 57 | b1b2.4 | TYR 184 | - | VdWContact |
| THR 75 | B3.2 | GLU 172 | - | HBDonor |
| THR 75 | B3.2 | GLU 172 | - | Hydrophobic |
| THR 75 | B3.2 | GLU 172 | - | VdWContact |
| THR 75 | B3.2 | GLY 173 | - | VdWContact |
| ASN 77 | B3.4 | HIS 175 | - | HBDonor |
| ASN 77 | B3.4 | HIS 175 | - | VdWContact |
| LEU 78 | b3h.1 | ILE 23 | 1.25x25 | Hydrophobic |
