Predicted complex interactions
CCL18_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL18_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 89
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm29 | TYR 108 | 3.32x32 | Hydrophobic |
| ALA 1 | NTc.Cm29 | PHE 109 | 3.33x33 | Hydrophobic |
| ALA 1 | NTc.Cm29 | GLU 283 | 7.39x38 | Cationic |
| ALA 1 | NTc.Cm29 | GLU 283 | 7.39x38 | VdWContact |
| GLN 2 | NTc.Cm28 | ASN 258 | 6.58x58 | VdWContact |
| GLN 2 | NTc.Cm28 | MET 279 | 7.35x34 | Hydrophobic |
| GLN 2 | NTc.Cm28 | MET 279 | 7.35x34 | VdWContact |
| GLN 2 | NTc.Cm28 | GLU 283 | 7.39x38 | HBDonor |
| GLN 2 | NTc.Cm28 | GLU 283 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm27 | TYR 37 | 1.39x39 | Hydrophobic |
| VAL 3 | NTc.Cm27 | TYR 37 | 1.39x39 | VdWContact |
| VAL 3 | NTc.Cm27 | TRP 86 | 2.60x60 | Hydrophobic |
| VAL 3 | NTc.Cm27 | TRP 86 | 2.60x60 | VdWContact |
| VAL 3 | NTc.Cm27 | TYR 108 | 3.32x32 | Hydrophobic |
| VAL 3 | NTc.Cm27 | GLU 283 | 7.39x38 | Hydrophobic |
| VAL 3 | NTc.Cm27 | MET 287 | 7.43x42 | Hydrophobic |
| GLY 4 | NTc.Cm26 | TYR 89 | 2.63x63 | VdWContact |
| THR 5 | NTc.Cm25 | GLN 280 | 7.36x35 | HBAcceptor |
| THR 5 | NTc.Cm25 | GLN 280 | 7.36x35 | VdWContact |
| ASN 6 | NTc.Cm24 | LYS 26 | 1.28x28 | HBAcceptor |
| ASN 6 | NTc.Cm24 | LYS 26 | 1.28x28 | VdWContact |
| ASN 6 | NTc.Cm24 | TYR 89 | 2.63x63 | Hydrophobic |
| ASN 6 | NTc.Cm24 | TYR 89 | 2.63x63 | VdWContact |
| ASN 6 | NTc.Cm24 | ALA 92 | 2.66x66 | HBDonor |
| ASN 6 | NTc.Cm24 | ALA 92 | 2.66x66 | VdWContact |
| ASN 6 | NTc.Cm24 | THR 177 | - | Hydrophobic |
| ASN 6 | NTc.Cm24 | THR 177 | - | VdWContact |
| LYS 7 | NTc.Cm23 | LYS 22 | 1.24x24 | Hydrophobic |
| LYS 7 | NTc.Cm23 | LYS 22 | 1.24x24 | VdWContact |
| LYS 7 | NTc.Cm23 | ASP 276 | 7.32x31 | Cationic |
| LYS 7 | NTc.Cm23 | ASP 276 | 7.32x31 | HBDonor |
| LYS 7 | NTc.Cm23 | ASP 276 | 7.32x31 | VdWContact |
| GLU 8 | NTc.Cm22 | LYS 22 | 1.24x24 | HBAcceptor |
| GLU 8 | NTc.Cm22 | LYS 22 | 1.24x24 | VdWContact |
| GLU 8 | NTc.Cm22 | LYS 26 | 1.28x28 | Anionic |
| GLU 8 | NTc.Cm22 | LYS 26 | 1.28x28 | HBAcceptor |
| GLU 8 | NTc.Cm22 | LYS 26 | 1.28x28 | Hydrophobic |
| GLU 8 | NTc.Cm22 | LYS 26 | 1.28x28 | VdWContact |
| LEU 9 | NTc.Cm21 | PRO 19 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 20 | - | VdWContact |
| LEU 9 | NTc.Cm21 | GLN 21 | - | VdWContact |
| CYS 10 | NTc.Cm20 | CYS 20 | - | HBAcceptor |
| CYS 10 | NTc.Cm20 | CYS 20 | - | HBDonor |
| CYS 10 | NTc.Cm20 | CYS 20 | - | VdWContact |
| CYS 10 | NTc.Cm20 | LYS 22 | 1.24x24 | Hydrophobic |
| CYS 10 | NTc.Cm20 | LYS 22 | 1.24x24 | VdWContact |
| LEU 12 | NTc.Cm18 | CYS 20 | - | Hydrophobic |
| LEU 12 | NTc.Cm18 | ASN 267 | - | VdWContact |
| LEU 12 | NTc.Cm18 | CYS 269 | 7.25x24 | Hydrophobic |
| LEU 12 | NTc.Cm18 | CYS 269 | 7.25x24 | VdWContact |
| TRP 17 | NTc.Cm13 | ASN 13 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | ASN 13 | - | VdWContact |
| ILE 19 | NTc.Cm11 | TYR 14 | - | Hydrophobic |
| ILE 19 | NTc.Cm11 | TYR 14 | - | VdWContact |
| PRO 20 | NTc.Cm10 | TYR 10 | - | Hydrophobic |
| GLU 29 | NTc.Cm1 | TYR 184 | - | HBAcceptor |
| GLU 29 | NTc.Cm1 | TYR 184 | - | VdWContact |
| SER 31 | CX.5 | GLU 172 | - | HBDonor |
| SER 31 | CX.5 | GLU 172 | - | VdWContact |
| PRO 32 | cxb1.1 | GLU 172 | - | VdWContact |
| PRO 32 | cxb1.1 | SER 179 | 45.51x51 | VdWContact |
| PRO 32 | cxb1.1 | SER 180 | 45.52x52 | VdWContact |
| PRO 32 | cxb1.1 | HIS 181 | - | Hydrophobic |
| PRO 32 | cxb1.1 | HIS 181 | - | VdWContact |
| PRO 32 | cxb1.1 | TYR 187 | 5.31x32 | HBAcceptor |
| PRO 32 | cxb1.1 | TYR 187 | 5.31x32 | VdWContact |
| CYS 34 | cxb1.5 | TYR 187 | 5.31x32 | VdWContact |
| CYS 34 | cxb1.5 | LYS 191 | 5.35x36 | VdWContact |
| PRO 35 | cxb1.6 | LYS 191 | 5.35x36 | HBAcceptor |
| PRO 35 | cxb1.6 | LYS 191 | 5.35x36 | VdWContact |
| LYS 36 | cxb1.7 | GLU 262 | 6.62x62 | Cationic |
| LYS 36 | cxb1.7 | GLU 262 | 6.62x62 | HBDonor |
| LYS 36 | cxb1.7 | GLU 262 | 6.62x62 | VdWContact |
| PRO 37 | cxb1.8 | TYR 184 | - | Hydrophobic |
| PRO 37 | cxb1.8 | TYR 184 | - | VdWContact |
| PRO 37 | cxb1.8 | TYR 187 | 5.31x32 | Hydrophobic |
| PRO 37 | cxb1.8 | TYR 187 | 5.31x32 | VdWContact |
| ILE 40 | cxb1.14 | PRO 19 | - | Hydrophobic |
| ARG 45 | B1.3 | SER 6 | - | VdWContact |
| ARG 45 | B1.3 | ASP 11 | - | Cationic |
| ARG 47 | B1.5 | ASP 11 | - | Cationic |
| ARG 47 | B1.5 | ASP 11 | - | HBDonor |
| ARG 47 | B1.5 | ASP 11 | - | VdWContact |
| GLN 48 | B1.6 | PRO 19 | - | Hydrophobic |
| ILE 49 | B1.7 | TYR 14 | - | Hydrophobic |
| ILE 49 | B1.7 | SER 17 | - | VdWContact |
| CYS 50 | b1b2.4 | SER 17 | - | HBDonor |
| CYS 50 | b1b2.4 | SER 17 | - | VdWContact |
| PRO 53 | b1b2.10 | TYR 184 | - | Hydrophobic |
