Predicted complex interactions
CCL19_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL19_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 85
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm28 | GLU 283 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm28 | GLU 283 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm28 | GLU 283 | 7.39x38 | VdWContact |
| GLY 1 | NTc.Cm28 | MET 287 | 7.43x42 | VdWContact |
| THR 2 | NTc.Cm27 | THR 105 | 3.29x29 | Hydrophobic |
| ASN 3 | NTc.Cm26 | MET 279 | 7.35x34 | Hydrophobic |
| ASN 3 | NTc.Cm26 | MET 279 | 7.35x34 | VdWContact |
| ASN 3 | NTc.Cm26 | GLU 283 | 7.39x38 | HBDonor |
| ASN 3 | NTc.Cm26 | GLU 283 | 7.39x38 | VdWContact |
| ASP 4 | NTc.Cm25 | TYR 89 | 2.63x63 | HBAcceptor |
| ASP 4 | NTc.Cm25 | TYR 89 | 2.63x63 | VdWContact |
| ASP 4 | NTc.Cm25 | SER 179 | 45.51x51 | VdWContact |
| ALA 5 | NTc.Cm24 | LYS 22 | 1.24x24 | Hydrophobic |
| ALA 5 | NTc.Cm24 | LYS 22 | 1.24x24 | VdWContact |
| ALA 5 | NTc.Cm24 | VAL 25 | 1.27x27 | Hydrophobic |
| ALA 5 | NTc.Cm24 | LYS 26 | 1.28x28 | Hydrophobic |
| ALA 5 | NTc.Cm24 | LYS 26 | 1.28x28 | VdWContact |
| ALA 5 | NTc.Cm24 | ASP 276 | 7.32x31 | Hydrophobic |
| GLU 6 | NTc.Cm23 | LYS 22 | 1.24x24 | HBAcceptor |
| GLU 6 | NTc.Cm23 | LYS 22 | 1.24x24 | VdWContact |
| GLU 6 | NTc.Cm23 | SER 179 | 45.51x51 | HBAcceptor |
| GLU 6 | NTc.Cm23 | SER 179 | 45.51x51 | VdWContact |
| ASP 7 | NTc.Cm22 | CYS 20 | - | VdWContact |
| ASP 7 | NTc.Cm22 | LYS 22 | 1.24x24 | HBAcceptor |
| ASP 7 | NTc.Cm22 | LYS 22 | 1.24x24 | VdWContact |
| ASP 7 | NTc.Cm22 | LYS 26 | 1.28x28 | Anionic |
| CYS 8 | NTc.Cm21 | CYS 20 | - | HBAcceptor |
| CYS 8 | NTc.Cm21 | CYS 20 | - | HBDonor |
| CYS 8 | NTc.Cm21 | CYS 20 | - | VdWContact |
| LEU 10 | NTc.Cm19 | CYS 20 | - | Hydrophobic |
| LEU 10 | NTc.Cm19 | ASN 267 | - | VdWContact |
| LEU 10 | NTc.Cm19 | CYS 269 | 7.25x24 | Hydrophobic |
| SER 11 | NTc.Cm18 | THR 16 | - | HBDonor |
| SER 11 | NTc.Cm18 | THR 16 | - | VdWContact |
| THR 13 | NTc.Cm16 | TYR 14 | - | Hydrophobic |
| THR 13 | NTc.Cm16 | SER 17 | - | VdWContact |
| LYS 15 | NTc.Cm14 | ILE 12 | - | Hydrophobic |
| LYS 15 | NTc.Cm14 | TYR 14 | - | Hydrophobic |
| LYS 15 | NTc.Cm14 | TYR 14 | - | VdWContact |
| PRO 16 | NTc.Cm13 | TYR 14 | - | HBAcceptor |
| PRO 16 | NTc.Cm13 | TYR 14 | - | VdWContact |
| ILE 17 | NTc.Cm12 | TYR 14 | - | Hydrophobic |
| ILE 17 | NTc.Cm12 | TYR 14 | - | VdWContact |
| PRO 18 | NTc.Cm11 | ILE 9 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | TYR 14 | - | VdWContact |
| TYR 20 | NTc.Cm9 | ILE 9 | - | Hydrophobic |
| TYR 20 | NTc.Cm9 | ILE 9 | - | VdWContact |
| ILE 21 | NTc.Cm8 | TYR 10 | - | Hydrophobic |
| LEU 28 | NTc.Cm1 | PRO 19 | - | Hydrophobic |
| ILE 30 | CX.5 | TYR 184 | - | Hydrophobic |
| ILE 30 | CX.5 | TYR 184 | - | VdWContact |
| ILE 30 | CX.5 | TYR 187 | 5.31x32 | Hydrophobic |
| ILE 30 | CX.5 | TYR 187 | 5.31x32 | VdWContact |
| LYS 31 | cxb1.1 | ARG 168 | - | HBAcceptor |
| LYS 31 | cxb1.1 | ARG 168 | - | VdWContact |
| LYS 31 | cxb1.1 | HIS 181 | - | VdWContact |
| ASP 32 | cxb1.2 | GLN 170 | - | HBAcceptor |
| ASP 32 | cxb1.2 | GLN 170 | - | VdWContact |
| GLY 33 | cxb1.5 | HIS 181 | - | VdWContact |
| GLY 33 | cxb1.5 | TYR 187 | 5.31x32 | HBAcceptor |
| GLY 33 | cxb1.5 | TYR 187 | 5.31x32 | VdWContact |
| ARG 35 | cxb1.8 | TYR 187 | 5.31x32 | Hydrophobic |
| ARG 35 | cxb1.8 | LYS 191 | 5.35x36 | VdWContact |
| ARG 35 | cxb1.8 | ASN 258 | 6.58x58 | HBDonor |
| ARG 35 | cxb1.8 | ASN 258 | 6.58x58 | VdWContact |
| ARG 35 | cxb1.8 | THR 259 | 6.59x59 | HBDonor |
| ARG 35 | cxb1.8 | THR 259 | 6.59x59 | VdWContact |
| ARG 35 | cxb1.8 | GLN 261 | 6.61x61 | VdWContact |
| PRO 37 | cxb1.10 | TYR 184 | - | Hydrophobic |
| PRO 37 | cxb1.10 | TYR 184 | - | VdWContact |
| VAL 40 | cxb1.15 | PRO 19 | - | Hydrophobic |
| ARG 45 | B1.4 | TYR 10 | - | CationPi |
| ARG 45 | B1.4 | TYR 10 | - | Hydrophobic |
| ARG 47 | B1.6 | TYR 15 | - | CationPi |
| ARG 47 | B1.6 | TYR 15 | - | VdWContact |
| ARG 47 | B1.6 | GLU 18 | - | Cationic |
| ARG 47 | B1.6 | GLU 18 | - | HBDonor |
| ARG 47 | B1.6 | GLU 18 | - | VdWContact |
| GLN 48 | B1.7 | GLU 18 | - | VdWContact |
| GLN 48 | B1.7 | PRO 19 | - | Hydrophobic |
| LEU 49 | b1b2.4 | TYR 14 | - | Hydrophobic |
| LEU 49 | b1b2.4 | TYR 14 | - | VdWContact |
| LEU 49 | b1b2.4 | SER 17 | - | VdWContact |
| CYS 50 | b1b2.6 | SER 17 | - | HBDonor |
| CYS 50 | b1b2.6 | SER 17 | - | VdWContact |
