Predicted complex interactions
CCL20_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL20_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 52
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm31 | MET 279 | 7.35x34 | Hydrophobic |
| ALA 1 | NTc.Cm31 | GLU 283 | 7.39x38 | Cationic |
| ASN 3 | NTc.Cm29 | LYS 26 | 1.28x28 | Hydrophobic |
| ASN 3 | NTc.Cm29 | LYS 26 | 1.28x28 | VdWContact |
| ASN 3 | NTc.Cm29 | GLN 280 | 7.36x35 | HBAcceptor |
| ASN 3 | NTc.Cm29 | GLN 280 | 7.36x35 | VdWContact |
| PHE 4 | NTc.Cm28 | LYS 22 | 1.24x24 | VdWContact |
| PHE 4 | NTc.Cm28 | GLU 172 | - | VdWContact |
| PHE 4 | NTc.Cm28 | THR 177 | - | Hydrophobic |
| PHE 4 | NTc.Cm28 | THR 177 | - | VdWContact |
| ASP 5 | NTc.Cm27 | CYS 20 | - | VdWContact |
| ASP 5 | NTc.Cm27 | LYS 22 | 1.24x24 | HBAcceptor |
| ASP 5 | NTc.Cm27 | LYS 22 | 1.24x24 | VdWContact |
| ASP 5 | NTc.Cm27 | LYS 26 | 1.28x28 | Anionic |
| ASP 5 | NTc.Cm27 | LYS 26 | 1.28x28 | HBAcceptor |
| ASP 5 | NTc.Cm27 | LYS 26 | 1.28x28 | VdWContact |
| CYS 6 | NTc.Cm26 | CYS 20 | - | HBAcceptor |
| CYS 6 | NTc.Cm26 | CYS 20 | - | VdWContact |
| LEU 8 | NTc.Cm24 | CYS 20 | - | Hydrophobic |
| LEU 8 | NTc.Cm24 | ASN 267 | - | VdWContact |
| LEU 8 | NTc.Cm24 | CYS 269 | 7.25x24 | Hydrophobic |
| LEU 8 | NTc.Cm24 | CYS 269 | 7.25x24 | VdWContact |
| THR 11 | NTc.Cm21 | SER 17 | - | VdWContact |
| ARG 13 | NTc.Cm19 | ILE 12 | - | VdWContact |
| LEU 15 | NTc.Cm17 | ILE 12 | - | Hydrophobic |
| LEU 15 | NTc.Cm17 | TYR 14 | - | Hydrophobic |
| LEU 15 | NTc.Cm17 | TYR 14 | - | VdWContact |
| ALA 28 | NTc.Cm4 | TYR 184 | - | Hydrophobic |
| ALA 28 | NTc.Cm4 | TYR 187 | 5.31x32 | Hydrophobic |
| ALA 28 | NTc.Cm4 | TYR 187 | 5.31x32 | VdWContact |
| ASN 29 | NTc.Cm3 | HIS 181 | - | HBAcceptor |
| ASN 29 | NTc.Cm3 | HIS 181 | - | VdWContact |
| ASN 29 | NTc.Cm3 | PHE 182 | - | VdWContact |
| GLU 30 | NTc.Cm2 | ARG 168 | - | Anionic |
| GLU 30 | NTc.Cm2 | HIS 181 | - | VdWContact |
| ASP 33 | CX.5 | TYR 187 | 5.31x32 | VdWContact |
| ASP 33 | CX.5 | LYS 191 | 5.35x36 | Anionic |
| ASP 33 | CX.5 | LYS 191 | 5.35x36 | HBAcceptor |
| ASP 33 | CX.5 | LYS 191 | 5.35x36 | VdWContact |
| ASN 35 | cxb1.2 | TYR 184 | - | VdWContact |
| ILE 38 | cxb1.7 | PRO 19 | - | Hydrophobic |
| THR 41 | cxb1.11 | TYR 14 | - | Hydrophobic |
| LYS 43 | cxb1.15 | ASP 11 | - | Cationic |
| LEU 45 | B1.1 | TYR 14 | - | Hydrophobic |
| LEU 45 | B1.1 | TYR 14 | - | VdWContact |
| SER 46 | B1.2 | GLU 18 | - | HBDonor |
| SER 46 | B1.2 | GLU 18 | - | VdWContact |
| VAL 47 | B1.3 | TYR 14 | - | Hydrophobic |
| VAL 47 | B1.3 | TYR 14 | - | VdWContact |
| VAL 47 | B1.3 | SER 17 | - | VdWContact |
| CYS 48 | B1.4 | SER 17 | - | HBDonor |
| CYS 48 | B1.4 | SER 17 | - | VdWContact |
