Predicted complex interactions
CCL21_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL21_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 70
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm30 | GLU 283 | 7.39x38 | Cationic |
| SER 1 | NTc.Cm30 | GLU 283 | 7.39x38 | HBDonor |
| SER 1 | NTc.Cm30 | GLU 283 | 7.39x38 | VdWContact |
| ASP 2 | NTc.Cm29 | TYR 89 | 2.63x63 | HBAcceptor |
| ASP 2 | NTc.Cm29 | TYR 89 | 2.63x63 | VdWContact |
| ASP 2 | NTc.Cm29 | SER 179 | 45.51x51 | VdWContact |
| GLY 3 | NTc.Cm28 | GLN 280 | 7.36x35 | HBAcceptor |
| GLY 3 | NTc.Cm28 | GLN 280 | 7.36x35 | VdWContact |
| GLY 4 | NTc.Cm27 | LYS 22 | 1.24x24 | HBAcceptor |
| GLY 4 | NTc.Cm27 | LYS 22 | 1.24x24 | VdWContact |
| GLY 4 | NTc.Cm27 | ASP 276 | 7.32x31 | VdWContact |
| ALA 5 | NTc.Cm26 | LYS 22 | 1.24x24 | VdWContact |
| ALA 5 | NTc.Cm26 | VAL 25 | 1.27x27 | Hydrophobic |
| ALA 5 | NTc.Cm26 | LYS 26 | 1.28x28 | Hydrophobic |
| ALA 5 | NTc.Cm26 | LYS 26 | 1.28x28 | VdWContact |
| GLN 6 | NTc.Cm25 | LYS 22 | 1.24x24 | VdWContact |
| ASP 7 | NTc.Cm24 | CYS 20 | - | VdWContact |
| ASP 7 | NTc.Cm24 | LYS 22 | 1.24x24 | HBAcceptor |
| ASP 7 | NTc.Cm24 | LYS 22 | 1.24x24 | VdWContact |
| ASP 7 | NTc.Cm24 | LYS 26 | 1.28x28 | Anionic |
| ASP 7 | NTc.Cm24 | LYS 26 | 1.28x28 | VdWContact |
| CYS 8 | NTc.Cm23 | CYS 20 | - | HBAcceptor |
| CYS 8 | NTc.Cm23 | CYS 20 | - | HBDonor |
| CYS 8 | NTc.Cm23 | CYS 20 | - | VdWContact |
| CYS 8 | NTc.Cm23 | LYS 22 | 1.24x24 | Anionic |
| LEU 10 | NTc.Cm21 | CYS 20 | - | Hydrophobic |
| LEU 10 | NTc.Cm21 | CYS 269 | 7.25x24 | Hydrophobic |
| SER 13 | NTc.Cm18 | TYR 14 | - | VdWContact |
| SER 13 | NTc.Cm18 | SER 17 | - | HBDonor |
| SER 13 | NTc.Cm18 | SER 17 | - | VdWContact |
| ARG 15 | NTc.Cm16 | ILE 12 | - | Hydrophobic |
| ARG 15 | NTc.Cm16 | ILE 12 | - | VdWContact |
| ARG 15 | NTc.Cm16 | TYR 14 | - | Hydrophobic |
| ARG 15 | NTc.Cm16 | TYR 14 | - | VdWContact |
| ILE 17 | NTc.Cm14 | TYR 14 | - | Hydrophobic |
| ILE 17 | NTc.Cm14 | TYR 14 | - | VdWContact |
| GLU 29 | NTc.Cm2 | ARG 168 | - | Anionic |
| GLU 29 | NTc.Cm2 | ARG 168 | - | HBAcceptor |
| GLU 29 | NTc.Cm2 | ARG 168 | - | VdWContact |
| PRO 30 | NTc.Cm1 | HIS 181 | - | HBAcceptor |
| PRO 30 | NTc.Cm1 | HIS 181 | - | VdWContact |
| PRO 30 | NTc.Cm1 | TYR 184 | - | Hydrophobic |
| PRO 30 | NTc.Cm1 | TYR 187 | 5.31x32 | Hydrophobic |
| PRO 30 | NTc.Cm1 | TYR 187 | 5.31x32 | VdWContact |
| SER 31 | CX.1 | SER 180 | 45.52x52 | VdWContact |
| SER 31 | CX.1 | HIS 181 | - | VdWContact |
| SER 31 | CX.1 | TYR 187 | 5.31x32 | HBAcceptor |
| SER 31 | CX.1 | TYR 187 | 5.31x32 | VdWContact |
| LEU 32 | CX.5 | SER 180 | 45.52x52 | HBDonor |
| LEU 32 | CX.5 | PHE 182 | - | Hydrophobic |
| LEU 32 | CX.5 | ASN 258 | 6.58x58 | HBAcceptor |
| SER 35 | cxb1.5 | TYR 187 | 5.31x32 | VdWContact |
| PRO 37 | cxb1.7 | TYR 184 | - | Hydrophobic |
| PRO 37 | cxb1.7 | TYR 184 | - | VdWContact |
| LEU 40 | cxb1.11 | PRO 19 | - | Hydrophobic |
| GLN 48 | B1.5 | ASP 11 | - | HBDonor |
| ALA 49 | B1.6 | GLU 18 | - | Hydrophobic |
| ALA 49 | B1.6 | GLU 18 | - | VdWContact |
| GLU 50 | B1.7 | GLU 18 | - | VdWContact |
| GLU 50 | B1.7 | PRO 19 | - | Hydrophobic |
| GLU 50 | B1.7 | PRO 19 | - | VdWContact |
| LEU 51 | b1b2.4 | TYR 14 | - | Hydrophobic |
| LEU 51 | b1b2.4 | TYR 14 | - | VdWContact |
| CYS 52 | b1b2.6 | SER 17 | - | HBDonor |
| CYS 52 | b1b2.6 | SER 17 | - | VdWContact |
| LYS 75 | B3.3 | GLN 170 | - | VdWContact |
| LYS 75 | B3.3 | LYS 171 | - | VdWContact |
| LYS 75 | B3.3 | GLU 172 | - | Cationic |
| LYS 75 | B3.3 | GLU 172 | - | HBDonor |
| LYS 75 | B3.3 | GLU 172 | - | VdWContact |
