Predicted complex interactions
CCL23_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL23_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 99
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 21 | NTc.Cm50 | LEU 174 | - | Hydrophobic |
| LEU 23 | NTc.Cm48 | ILE 23 | 1.25x25 | Hydrophobic |
| LEU 23 | NTc.Cm48 | GLN 27 | 1.29x29 | Hydrophobic |
| LEU 23 | NTc.Cm48 | GLN 27 | 1.29x29 | VdWContact |
| ASP 24 | NTc.Cm47 | LYS 26 | 1.28x28 | Anionic |
| ASP 24 | NTc.Cm47 | HIS 175 | - | Hydrophobic |
| ASP 24 | NTc.Cm47 | HIS 175 | - | VdWContact |
| ARG 25 | NTc.Cm46 | ALA 92 | 2.66x66 | VdWContact |
| ARG 25 | NTc.Cm46 | HIS 175 | - | Hydrophobic |
| PHE 26 | NTc.Cm45 | LYS 26 | 1.28x28 | Hydrophobic |
| PHE 26 | NTc.Cm45 | LYS 26 | 1.28x28 | VdWContact |
| PHE 26 | NTc.Cm45 | GLN 27 | 1.29x29 | Hydrophobic |
| PHE 26 | NTc.Cm45 | ALA 30 | 1.32x32 | Hydrophobic |
| PHE 26 | NTc.Cm45 | ALA 30 | 1.32x32 | VdWContact |
| PHE 26 | NTc.Cm45 | ALA 91 | 2.65x65 | VdWContact |
| HIS 27 | NTc.Cm44 | TYR 89 | 2.63x63 | Hydrophobic |
| HIS 27 | NTc.Cm44 | TYR 89 | 2.63x63 | VdWContact |
| HIS 27 | NTc.Cm44 | ALA 90 | 2.64x64 | VdWContact |
| HIS 27 | NTc.Cm44 | ALA 92 | 2.66x66 | HBDonor |
| HIS 27 | NTc.Cm44 | ALA 92 | 2.66x66 | VdWContact |
| HIS 27 | NTc.Cm44 | GLN 93 | 23.49x49 | Hydrophobic |
| HIS 27 | NTc.Cm44 | GLN 93 | 23.49x49 | VdWContact |
| HIS 27 | NTc.Cm44 | HIS 175 | - | Hydrophobic |
| HIS 27 | NTc.Cm44 | HIS 175 | - | VdWContact |
| HIS 27 | NTc.Cm44 | TYR 176 | - | VdWContact |
| HIS 27 | NTc.Cm44 | THR 177 | - | Hydrophobic |
| HIS 27 | NTc.Cm44 | THR 177 | - | VdWContact |
| ALA 28 | NTc.Cm43 | LYS 26 | 1.28x28 | Hydrophobic |
| ALA 28 | NTc.Cm43 | LYS 26 | 1.28x28 | VdWContact |
| ALA 28 | NTc.Cm43 | ALA 29 | 1.31x31 | Hydrophobic |
| ALA 28 | NTc.Cm43 | ALA 29 | 1.31x31 | VdWContact |
| THR 29 | NTc.Cm42 | TYR 89 | 2.63x63 | Hydrophobic |
| SER 30 | NTc.Cm41 | LYS 22 | 1.24x24 | VdWContact |
| SER 30 | NTc.Cm41 | LYS 26 | 1.28x28 | VdWContact |
| SER 30 | NTc.Cm41 | ASP 276 | 7.32x31 | VdWContact |
| ALA 31 | NTc.Cm40 | LYS 22 | 1.24x24 | VdWContact |
| ASP 32 | NTc.Cm39 | PRO 19 | - | Hydrophobic |
| ASP 32 | NTc.Cm39 | CYS 20 | - | VdWContact |
| ASP 32 | NTc.Cm39 | GLN 21 | - | VdWContact |
| ASP 32 | NTc.Cm39 | LYS 22 | 1.24x24 | HBAcceptor |
| ASP 32 | NTc.Cm39 | LYS 22 | 1.24x24 | VdWContact |
| ASP 32 | NTc.Cm39 | LYS 26 | 1.28x28 | Anionic |
| CYS 33 | NTc.Cm38 | CYS 20 | - | HBAcceptor |
| CYS 33 | NTc.Cm38 | CYS 20 | - | HBDonor |
| CYS 33 | NTc.Cm38 | CYS 20 | - | VdWContact |
| CYS 33 | NTc.Cm38 | LYS 22 | 1.24x24 | Anionic |
| CYS 33 | NTc.Cm38 | LYS 22 | 1.24x24 | VdWContact |
| ILE 35 | NTc.Cm36 | CYS 20 | - | Hydrophobic |
| ILE 35 | NTc.Cm36 | ASN 267 | - | VdWContact |
| SER 36 | NTc.Cm35 | THR 16 | - | HBDonor |
| SER 36 | NTc.Cm35 | THR 16 | - | VdWContact |
| ARG 40 | NTc.Cm31 | ILE 12 | - | VdWContact |
| ILE 42 | NTc.Cm29 | TYR 14 | - | Hydrophobic |
| ILE 42 | NTc.Cm29 | TYR 14 | - | VdWContact |
| PHE 51 | NTc.Cm20 | GLU 172 | - | Hydrophobic |
| PHE 51 | NTc.Cm20 | GLU 172 | - | VdWContact |
| GLU 52 | NTc.Cm19 | ARG 168 | - | Anionic |
| GLU 52 | NTc.Cm19 | ARG 168 | - | HBAcceptor |
| GLU 52 | NTc.Cm19 | ARG 168 | - | VdWContact |
| GLU 52 | NTc.Cm19 | GLN 170 | - | HBAcceptor |
| GLU 52 | NTc.Cm19 | GLN 170 | - | VdWContact |
| GLU 52 | NTc.Cm19 | HIS 181 | - | VdWContact |
| THR 53 | NTc.Cm18 | HIS 181 | - | HBAcceptor |
| THR 53 | NTc.Cm18 | HIS 181 | - | VdWContact |
| ASN 54 | NTc.Cm17 | HIS 181 | - | Hydrophobic |
| SER 55 | NTc.Cm16 | SER 180 | 45.52x52 | HBDonor |
| SER 55 | NTc.Cm16 | SER 180 | 45.52x52 | VdWContact |
| SER 55 | NTc.Cm16 | HIS 181 | - | HBDonor |
| SER 55 | NTc.Cm16 | HIS 181 | - | VdWContact |
| SER 55 | NTc.Cm16 | PHE 182 | - | HBAcceptor |
| SER 55 | NTc.Cm16 | PHE 182 | - | VdWContact |
| SER 55 | NTc.Cm16 | TYR 187 | 5.31x32 | VdWContact |
| SER 55 | NTc.Cm16 | LYS 191 | 5.35x36 | VdWContact |
| GLU 56 | NTc.Cm15 | LYS 191 | 5.35x36 | HBAcceptor |
| GLU 56 | NTc.Cm15 | LYS 191 | 5.35x36 | VdWContact |
| GLU 56 | NTc.Cm15 | ASN 258 | 6.58x58 | HBAcceptor |
| CYS 57 | NTc.Cm14 | TYR 187 | 5.31x32 | HBAcceptor |
| CYS 57 | NTc.Cm14 | TYR 187 | 5.31x32 | VdWContact |
| CYS 57 | NTc.Cm14 | LYS 191 | 5.35x36 | HBAcceptor |
| CYS 57 | NTc.Cm14 | LYS 191 | 5.35x36 | VdWContact |
| SER 58 | NTc.Cm13 | GLN 261 | 6.61x61 | VdWContact |
| LYS 59 | NTc.Cm12 | GLU 262 | 6.62x62 | Cationic |
| LYS 59 | NTc.Cm12 | GLU 262 | 6.62x62 | HBDonor |
| LYS 59 | NTc.Cm12 | GLU 262 | 6.62x62 | VdWContact |
| PRO 60 | NTc.Cm11 | TYR 184 | - | Hydrophobic |
| PRO 60 | NTc.Cm11 | TYR 187 | 5.31x32 | Hydrophobic |
| PRO 60 | NTc.Cm11 | TYR 187 | 5.31x32 | VdWContact |
| ILE 63 | NTc.Cm8 | PRO 19 | - | Hydrophobic |
| ARG 70 | NTc.Cm1 | ASP 11 | - | Cationic |
| ARG 70 | NTc.Cm1 | ASP 11 | - | HBDonor |
| ARG 70 | NTc.Cm1 | ASP 11 | - | VdWContact |
| ARG 71 | CX.1 | PRO 19 | - | Hydrophobic |
| PHE 72 | CX.5 | TYR 14 | - | Hydrophobic |
| PHE 72 | CX.5 | TYR 14 | - | PiStacking |
| CYS 73 | cxb1.1 | SER 17 | - | HBDonor |
| CYS 73 | cxb1.1 | SER 17 | - | VdWContact |
| PRO 76 | cxb1.6 | TYR 184 | - | Hydrophobic |
| SER 77 | cxb1.7 | TYR 184 | - | VdWContact |
| GLN 82 | cxb1.15 | TYR 184 | - | VdWContact |
