Predicted complex interactions
CXCL8_HUMAN + ACKR1
SUMMARY
- Chemokine
- CXCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR1 View partner entry
- Partner description
- UniProt: Q16570; Gene: ackr1_human; Family: Chemokine
- Interactions detected
- 114
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 4 | NTc.Cm30 | ARG 7 | - | VdWContact |
| LYS 10 | NTc.Cm24 | ASN 55 | - | HBAcceptor |
| LYS 10 | NTc.Cm24 | ASN 55 | - | VdWContact |
| LYS 10 | NTc.Cm24 | ASP 59 | 1.33x33 | Cationic |
| LYS 10 | NTc.Cm24 | ASP 59 | 1.33x33 | HBDonor |
| LYS 10 | NTc.Cm24 | ASP 59 | 1.33x33 | VdWContact |
| GLU 11 | NTc.Cm23 | HIS 52 | - | HBAcceptor |
| GLU 11 | NTc.Cm23 | HIS 52 | - | VdWContact |
| GLU 11 | NTc.Cm23 | SER 53 | - | HBAcceptor |
| GLU 11 | NTc.Cm23 | SER 53 | - | VdWContact |
| LEU 12 | NTc.Cm22 | ARG 267 | 6.62x62 | HBAcceptor |
| LEU 12 | NTc.Cm22 | ARG 267 | 6.62x62 | VdWContact |
| LEU 12 | NTc.Cm22 | ASP 283 | 7.32x31 | Hydrophobic |
| ARG 13 | NTc.Cm21 | ASP 263 | 6.58x58 | Cationic |
| ARG 13 | NTc.Cm21 | ASP 263 | 6.58x58 | HBDonor |
| ARG 13 | NTc.Cm21 | ASP 263 | 6.58x58 | VdWContact |
| ARG 13 | NTc.Cm21 | GLN 279 | 7.28x27 | Hydrophobic |
| ARG 13 | NTc.Cm21 | GLN 279 | 7.28x27 | VdWContact |
| ARG 13 | NTc.Cm21 | ASP 283 | 7.32x31 | Cationic |
| ARG 13 | NTc.Cm21 | ASP 283 | 7.32x31 | HBDonor |
| ARG 13 | NTc.Cm21 | ASP 283 | 7.32x31 | VdWContact |
| ARG 13 | NTc.Cm21 | LEU 286 | 7.35x34 | VdWContact |
| CYS 14 | NTc.Cm20 | GLN 279 | 7.28x27 | HBAcceptor |
| CYS 14 | NTc.Cm20 | GLN 279 | 7.28x27 | VdWContact |
| GLN 15 | NTc.Cm19 | PRO 50 | - | Hydrophobic |
| GLN 15 | NTc.Cm19 | CYS 51 | - | HBAcceptor |
| GLN 15 | NTc.Cm19 | CYS 51 | - | VdWContact |
| GLN 15 | NTc.Cm19 | HIS 52 | - | VdWContact |
| ILE 17 | NTc.Cm17 | CYS 51 | - | Hydrophobic |
| ILE 17 | NTc.Cm17 | CYS 276 | 7.25x24 | Hydrophobic |
| ILE 17 | NTc.Cm17 | CYS 276 | 7.25x24 | VdWContact |
| ILE 17 | NTc.Cm17 | GLN 279 | 7.28x27 | Hydrophobic |
| LYS 18 | NTc.Cm16 | ALA 47 | - | Hydrophobic |
| LYS 18 | NTc.Cm16 | ALA 47 | - | VdWContact |
| LYS 18 | NTc.Cm16 | ALA 48 | - | VdWContact |
| TYR 20 | NTc.Cm14 | PRO 37 | - | Hydrophobic |
| TYR 20 | NTc.Cm14 | LEU 45 | - | Hydrophobic |
| TYR 20 | NTc.Cm14 | ALA 48 | - | Hydrophobic |
| PRO 23 | NTc.Cm11 | TYR 30 | - | Hydrophobic |
| PRO 23 | NTc.Cm11 | VAL 32 | - | Hydrophobic |
| PRO 23 | NTc.Cm11 | VAL 32 | - | VdWContact |
| PHE 24 | NTc.Cm10 | VAL 32 | - | VdWContact |
| PHE 24 | NTc.Cm10 | PRO 37 | - | Hydrophobic |
| HIS 25 | NTc.Cm9 | GLU 23 | - | Hydrophobic |
| HIS 25 | NTc.Cm9 | GLU 23 | - | VdWContact |
| HIS 25 | NTc.Cm9 | TRP 26 | - | Hydrophobic |
| HIS 25 | NTc.Cm9 | TRP 26 | - | VdWContact |
| PRO 26 | NTc.Cm8 | PHE 22 | - | Hydrophobic |
| LYS 27 | NTc.Cm7 | GLU 23 | - | Cationic |
| LYS 27 | NTc.Cm7 | GLU 23 | - | VdWContact |
| LYS 27 | NTc.Cm7 | ASP 34 | - | Cationic |
| LYS 27 | NTc.Cm7 | ASP 34 | - | HBDonor |
| LYS 27 | NTc.Cm7 | ASP 34 | - | VdWContact |
| PHE 28 | NTc.Cm6 | ASP 34 | - | VdWContact |
| PHE 28 | NTc.Cm6 | SER 35 | - | VdWContact |
| PHE 28 | NTc.Cm6 | PHE 36 | - | Hydrophobic |
| PHE 28 | NTc.Cm6 | PHE 36 | - | VdWContact |
| ILE 29 | NTc.Cm5 | LEU 10 | - | VdWContact |
| GLU 31 | NTc.Cm3 | ARG 7 | - | Anionic |
| GLU 31 | NTc.Cm3 | ARG 7 | - | HBAcceptor |
| GLU 31 | NTc.Cm3 | ARG 7 | - | Hydrophobic |
| GLU 31 | NTc.Cm3 | ARG 7 | - | VdWContact |
| PRO 39 | cxb1.5 | SER 191 | - | VdWContact |
| PRO 39 | cxb1.5 | ILE 198 | - | Hydrophobic |
| PRO 39 | cxb1.5 | ILE 198 | - | VdWContact |
| PRO 39 | cxb1.5 | TYR 199 | - | HBAcceptor |
| PRO 39 | cxb1.5 | TYR 199 | - | VdWContact |
| HIS 40 | cxb1.6 | THR 196 | 45.51x51 | Hydrophobic |
| HIS 40 | cxb1.6 | THR 196 | 45.51x51 | VdWContact |
| HIS 40 | cxb1.6 | ARG 267 | 6.62x62 | HBAcceptor |
| HIS 40 | cxb1.6 | ARG 267 | 6.62x62 | VdWContact |
| ILE 47 | cxb1.16 | PRO 50 | - | Hydrophobic |
| LEU 50 | B1.3 | PHE 36 | - | Hydrophobic |
| LEU 50 | B1.3 | PRO 37 | - | Hydrophobic |
| LEU 50 | B1.3 | PRO 37 | - | VdWContact |
| SER 51 | B1.4 | PHE 36 | - | VdWContact |
| ASP 52 | B1.5 | PHE 36 | - | Hydrophobic |
| ASP 52 | B1.5 | PHE 36 | - | VdWContact |
| ARG 54 | B1.7 | PHE 36 | - | VdWContact |
| ARG 54 | B1.7 | PRO 37 | - | HBDonor |
| ARG 54 | B1.7 | PRO 37 | - | VdWContact |
| ARG 54 | B1.7 | ASP 38 | - | Cationic |
| ARG 54 | B1.7 | LEU 45 | - | VdWContact |
| GLU 55 | b1b2.4 | ALA 49 | - | VdWContact |
| GLU 55 | b1b2.4 | PRO 50 | - | Hydrophobic |
| LEU 56 | b1b2.6 | LEU 45 | - | Hydrophobic |
| LEU 56 | b1b2.6 | LEU 45 | - | VdWContact |
| LEU 56 | b1b2.6 | ALA 48 | - | Hydrophobic |
| CYS 57 | b1b2.7 | ALA 48 | - | HBDonor |
| CYS 57 | b1b2.7 | ALA 48 | - | VdWContact |
| ASN 63 | b1b2.14 | TYR 30 | - | HBAcceptor |
| ASN 63 | b1b2.14 | TYR 30 | - | VdWContact |
| TRP 64 | b1b2.16 | TRP 26 | - | Hydrophobic |
| TRP 64 | b1b2.16 | TRP 26 | - | VdWContact |
| TRP 64 | b1b2.16 | TYR 30 | - | Hydrophobic |
| TRP 64 | b1b2.16 | TYR 30 | - | VdWContact |
| ARG 67 | B2.3 | TRP 26 | - | Hydrophobic |
| ARG 67 | B2.3 | TRP 26 | - | VdWContact |
| ARG 67 | B2.3 | SER 29 | - | HBDonor |
| ARG 67 | B2.3 | TYR 30 | - | VdWContact |
| VAL 68 | B2.4 | TRP 26 | - | Hydrophobic |
| VAL 68 | B2.4 | TRP 26 | - | VdWContact |
| LYS 71 | b2b3.2 | PHE 22 | - | Hydrophobic |
| LYS 71 | b2b3.2 | PHE 22 | - | VdWContact |
| PHE 72 | b2b3.4 | ALA 8 | - | Hydrophobic |
| PHE 72 | b2b3.4 | LEU 10 | - | Hydrophobic |
| PHE 72 | b2b3.4 | LEU 10 | - | VdWContact |
| LEU 73 | b2b3.11 | LEU 5 | - | Hydrophobic |
| LEU 73 | b2b3.11 | LEU 5 | - | VdWContact |
| ARG 75 | B3.1 | LEU 10 | - | VdWContact |
| ARG 75 | B3.1 | SER 11 | - | VdWContact |
| ARG 75 | B3.1 | PRO 12 | - | VdWContact |
| ALA 76 | B3.2 | ALA 8 | - | Hydrophobic |
| ALA 76 | B3.2 | ALA 8 | - | VdWContact |
