Predicted complex interactions
CCL25_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 87
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | TRP 86 | 2.60x60 | Hydrophobic |
| GLN 1 | NTc.Cm29 | TRP 86 | 2.60x60 | VdWContact |
| GLN 1 | NTc.Cm29 | TYR 108 | 3.32x32 | Hydrophobic |
| GLN 1 | NTc.Cm29 | TYR 108 | 3.32x32 | VdWContact |
| GLN 1 | NTc.Cm29 | GLU 283 | 7.39x38 | Cationic |
| GLN 1 | NTc.Cm29 | GLU 283 | 7.39x38 | HBDonor |
| GLN 1 | NTc.Cm29 | GLU 283 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm27 | LYS 26 | 1.28x28 | Hydrophobic |
| VAL 3 | NTc.Cm27 | TYR 89 | 2.63x63 | Hydrophobic |
| VAL 3 | NTc.Cm27 | TYR 89 | 2.63x63 | VdWContact |
| PHE 4 | NTc.Cm26 | LYS 22 | 1.24x24 | Hydrophobic |
| PHE 4 | NTc.Cm26 | LYS 22 | 1.24x24 | VdWContact |
| PHE 4 | NTc.Cm26 | VAL 25 | 1.27x27 | Hydrophobic |
| PHE 4 | NTc.Cm26 | LYS 26 | 1.28x28 | VdWContact |
| PHE 4 | NTc.Cm26 | ASP 276 | 7.32x31 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ASP 276 | 7.32x31 | VdWContact |
| PHE 4 | NTc.Cm26 | MET 279 | 7.35x34 | Hydrophobic |
| PHE 4 | NTc.Cm26 | MET 279 | 7.35x34 | VdWContact |
| PHE 4 | NTc.Cm26 | GLN 280 | 7.36x35 | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLN 280 | 7.36x35 | VdWContact |
| GLU 5 | NTc.Cm25 | LYS 22 | 1.24x24 | VdWContact |
| GLU 5 | NTc.Cm25 | GLU 172 | - | VdWContact |
| GLU 5 | NTc.Cm25 | THR 177 | - | HBAcceptor |
| GLU 5 | NTc.Cm25 | THR 177 | - | Hydrophobic |
| GLU 5 | NTc.Cm25 | THR 177 | - | VdWContact |
| GLU 5 | NTc.Cm25 | SER 179 | 45.51x51 | HBAcceptor |
| GLU 5 | NTc.Cm25 | SER 179 | 45.51x51 | VdWContact |
| ASP 6 | NTc.Cm24 | CYS 20 | - | VdWContact |
| ASP 6 | NTc.Cm24 | GLN 21 | - | VdWContact |
| ASP 6 | NTc.Cm24 | LYS 22 | 1.24x24 | HBAcceptor |
| ASP 6 | NTc.Cm24 | LYS 22 | 1.24x24 | VdWContact |
| ASP 6 | NTc.Cm24 | LYS 26 | 1.28x28 | Anionic |
| CYS 7 | NTc.Cm23 | CYS 20 | - | HBAcceptor |
| CYS 7 | NTc.Cm23 | CYS 20 | - | HBDonor |
| CYS 7 | NTc.Cm23 | CYS 20 | - | VdWContact |
| CYS 7 | NTc.Cm23 | LYS 22 | 1.24x24 | Anionic |
| LEU 9 | NTc.Cm21 | CYS 20 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | ASN 267 | - | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 269 | 7.25x24 | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 269 | 7.25x24 | VdWContact |
| HIS 12 | NTc.Cm18 | THR 16 | - | VdWContact |
| VAL 19 | NTc.Cm11 | ILE 12 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | TYR 14 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | TYR 14 | - | VdWContact |
| ARG 27 | NTc.Cm3 | GLU 172 | - | Cationic |
| ARG 27 | NTc.Cm3 | GLU 172 | - | HBDonor |
| ARG 27 | NTc.Cm3 | GLU 172 | - | VdWContact |
| GLU 30 | CX.1 | ARG 168 | - | Anionic |
| GLU 30 | CX.1 | ARG 168 | - | HBAcceptor |
| GLU 30 | CX.1 | ARG 168 | - | VdWContact |
| GLU 30 | CX.1 | HIS 181 | - | VdWContact |
| VAL 31 | CX.5 | PHE 182 | - | HBAcceptor |
| VAL 31 | CX.5 | PHE 182 | - | Hydrophobic |
| VAL 31 | CX.5 | PHE 182 | - | VdWContact |
| VAL 31 | CX.5 | TYR 187 | 5.31x32 | Hydrophobic |
| VAL 31 | CX.5 | TYR 187 | 5.31x32 | VdWContact |
| VAL 31 | CX.5 | LYS 191 | 5.35x36 | Hydrophobic |
| VAL 31 | CX.5 | LYS 191 | 5.35x36 | VdWContact |
| SER 32 | cxb1.1 | SER 180 | 45.52x52 | VdWContact |
| SER 32 | cxb1.1 | LYS 191 | 5.35x36 | HBAcceptor |
| SER 32 | cxb1.1 | LYS 191 | 5.35x36 | VdWContact |
| GLY 33 | cxb1.2 | ASN 258 | 6.58x58 | HBAcceptor |
| GLY 33 | cxb1.2 | ASN 258 | 6.58x58 | VdWContact |
| SER 34 | cxb1.5 | LYS 22 | 1.24x24 | HBAcceptor |
| SER 34 | cxb1.5 | LYS 22 | 1.24x24 | VdWContact |
| ASN 36 | cxb1.8 | LYS 191 | 5.35x36 | HBAcceptor |
| ASN 36 | cxb1.8 | LYS 191 | 5.35x36 | VdWContact |
| ASN 36 | cxb1.8 | ASN 258 | 6.58x58 | HBDonor |
| ASN 36 | cxb1.8 | ASN 258 | 6.58x58 | VdWContact |
| ASN 36 | cxb1.8 | GLN 261 | 6.61x61 | HBDonor |
| ASN 36 | cxb1.8 | GLN 261 | 6.61x61 | VdWContact |
| PRO 38 | cxb1.11 | TYR 184 | - | Hydrophobic |
| PRO 38 | cxb1.11 | TYR 184 | - | VdWContact |
| PRO 38 | cxb1.11 | TYR 187 | 5.31x32 | Hydrophobic |
| ILE 41 | cxb1.16 | PRO 19 | - | Hydrophobic |
| ARG 49 | b1b2.1 | ASP 11 | - | Cationic |
| ARG 49 | b1b2.1 | ASP 11 | - | HBDonor |
| ARG 49 | b1b2.1 | ASP 11 | - | VdWContact |
| ARG 49 | b1b2.1 | GLU 18 | - | Cationic |
| LYS 50 | b1b2.2 | GLU 18 | - | VdWContact |
| LYS 50 | b1b2.2 | PRO 19 | - | Hydrophobic |
| VAL 51 | b1b2.3 | SER 17 | - | VdWContact |
| CYS 52 | b1b2.4 | SER 17 | - | HBDonor |
| CYS 52 | b1b2.4 | SER 17 | - | VdWContact |
| PRO 55 | b1b2.7 | TYR 184 | - | Hydrophobic |
| LYS 56 | b1b2.9 | TYR 184 | - | Hydrophobic |
| LYS 56 | b1b2.9 | TYR 184 | - | VdWContact |
