Predicted complex interactions
CCL27_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL27_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 79
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PHE 1 | NTc.Cm32 | THR 105 | 3.29x29 | Hydrophobic |
| PHE 1 | NTc.Cm32 | THR 105 | 3.29x29 | VdWContact |
| PHE 1 | NTc.Cm32 | TYR 108 | 3.32x32 | Hydrophobic |
| PHE 1 | NTc.Cm32 | PHE 109 | 3.33x33 | Hydrophobic |
| PHE 1 | NTc.Cm32 | PHE 109 | 3.33x33 | VdWContact |
| PHE 1 | NTc.Cm32 | GLU 283 | 7.39x38 | Cationic |
| PHE 1 | NTc.Cm32 | GLU 283 | 7.39x38 | HBDonor |
| PHE 1 | NTc.Cm32 | GLU 283 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm31 | SER 180 | 45.52x52 | VdWContact |
| LEU 3 | NTc.Cm30 | ASP 276 | 7.32x31 | Hydrophobic |
| PRO 4 | NTc.Cm29 | LYS 26 | 1.28x28 | VdWContact |
| PRO 4 | NTc.Cm29 | TYR 89 | 2.63x63 | Hydrophobic |
| PRO 4 | NTc.Cm29 | TYR 89 | 2.63x63 | VdWContact |
| PRO 4 | NTc.Cm29 | THR 177 | - | Hydrophobic |
| PRO 4 | NTc.Cm29 | THR 177 | - | VdWContact |
| PRO 5 | NTc.Cm28 | LYS 26 | 1.28x28 | HBAcceptor |
| PRO 5 | NTc.Cm28 | LYS 26 | 1.28x28 | Hydrophobic |
| PRO 5 | NTc.Cm28 | LYS 26 | 1.28x28 | VdWContact |
| SER 6 | NTc.Cm27 | LYS 26 | 1.28x28 | HBAcceptor |
| SER 6 | NTc.Cm27 | LYS 26 | 1.28x28 | VdWContact |
| THR 7 | NTc.Cm26 | LYS 22 | 1.24x24 | HBAcceptor |
| THR 7 | NTc.Cm26 | LYS 22 | 1.24x24 | VdWContact |
| THR 7 | NTc.Cm26 | ILE 23 | 1.25x25 | Hydrophobic |
| ALA 8 | NTc.Cm25 | PRO 19 | - | Hydrophobic |
| ALA 8 | NTc.Cm25 | CYS 20 | - | VdWContact |
| CYS 9 | NTc.Cm24 | CYS 20 | - | HBAcceptor |
| CYS 9 | NTc.Cm24 | CYS 20 | - | HBDonor |
| CYS 9 | NTc.Cm24 | CYS 20 | - | VdWContact |
| CYS 9 | NTc.Cm24 | LYS 22 | 1.24x24 | Hydrophobic |
| CYS 9 | NTc.Cm24 | LYS 22 | 1.24x24 | VdWContact |
| THR 11 | NTc.Cm22 | CYS 20 | - | Hydrophobic |
| THR 11 | NTc.Cm22 | ASN 267 | - | VdWContact |
| GLN 12 | NTc.Cm21 | ASN 267 | - | HBDonor |
| GLN 12 | NTc.Cm21 | ASN 267 | - | VdWContact |
| TYR 14 | NTc.Cm19 | ILE 12 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | ILE 12 | - | VdWContact |
| TYR 14 | NTc.Cm19 | TYR 14 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | TYR 14 | - | VdWContact |
| ARG 15 | NTc.Cm18 | GLU 262 | 6.62x62 | Cationic |
| LEU 18 | NTc.Cm15 | TYR 14 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | TYR 14 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | TYR 14 | - | VdWContact |
| GLU 33 | CX.1 | ARG 168 | - | Anionic |
| GLU 33 | CX.1 | ARG 168 | - | HBAcceptor |
| GLU 33 | CX.1 | ARG 168 | - | VdWContact |
| GLU 33 | CX.1 | HIS 181 | - | HBAcceptor |
| GLU 33 | CX.1 | HIS 181 | - | VdWContact |
| ALA 34 | CX.5 | TYR 187 | 5.31x32 | Hydrophobic |
| ALA 34 | CX.5 | TYR 187 | 5.31x32 | VdWContact |
| ASP 35 | cxb1.1 | SER 179 | 45.51x51 | VdWContact |
| ASP 35 | cxb1.1 | SER 180 | 45.52x52 | VdWContact |
| ASP 35 | cxb1.1 | HIS 181 | - | Hydrophobic |
| ASP 35 | cxb1.1 | HIS 181 | - | VdWContact |
| GLY 36 | cxb1.2 | SER 179 | 45.51x51 | HBDonor |
| GLY 36 | cxb1.2 | SER 179 | 45.51x51 | VdWContact |
| HIS 39 | cxb1.7 | LYS 191 | 5.35x36 | VdWContact |
| HIS 39 | cxb1.7 | ASN 258 | 6.58x58 | HBAcceptor |
| HIS 39 | cxb1.7 | ASN 258 | 6.58x58 | VdWContact |
| HIS 39 | cxb1.7 | GLN 261 | 6.61x61 | VdWContact |
| GLN 41 | cxb1.10 | TYR 184 | - | Hydrophobic |
| GLN 41 | cxb1.10 | TYR 184 | - | VdWContact |
| VAL 44 | cxb1.15 | PRO 19 | - | Hydrophobic |
| ARG 50 | B1.2 | ASP 11 | - | Cationic |
| ARG 50 | B1.2 | ASP 11 | - | HBDonor |
| ARG 50 | B1.2 | ASP 11 | - | VdWContact |
| ARG 50 | B1.2 | GLU 18 | - | Cationic |
| ARG 50 | B1.2 | GLU 18 | - | VdWContact |
| SER 51 | B1.3 | GLU 18 | - | VdWContact |
| SER 51 | B1.3 | PRO 19 | - | VdWContact |
| ILE 52 | B1.4 | TYR 14 | - | Hydrophobic |
| ILE 52 | B1.4 | TYR 14 | - | VdWContact |
| ILE 52 | B1.4 | SER 17 | - | VdWContact |
| CYS 53 | B1.5 | SER 17 | - | HBDonor |
| CYS 53 | B1.5 | SER 17 | - | VdWContact |
| PRO 56 | b1b2.4 | TYR 184 | - | Hydrophobic |
| PRO 56 | b1b2.4 | TYR 184 | - | VdWContact |
| GLN 57 | b1b2.6 | TYR 184 | - | VdWContact |
| MET 87 | H.5 | TYR 184 | - | Hydrophobic |
| MET 87 | H.5 | TYR 184 | - | VdWContact |
