Predicted complex interactions
CCL3_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL3_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 100
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm33 | TYR 251 | 6.51x51 | HBDonor |
| SER 1 | NTc.Cm33 | TYR 251 | 6.51x51 | VdWContact |
| SER 1 | NTc.Cm33 | GLU 283 | 7.39x38 | Cationic |
| SER 1 | NTc.Cm33 | GLU 283 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm32 | TRP 86 | 2.60x60 | Hydrophobic |
| LEU 2 | NTc.Cm32 | TRP 86 | 2.60x60 | VdWContact |
| LEU 2 | NTc.Cm32 | THR 105 | 3.29x29 | Hydrophobic |
| LEU 2 | NTc.Cm32 | TYR 108 | 3.32x32 | Hydrophobic |
| LEU 2 | NTc.Cm32 | TYR 108 | 3.32x32 | VdWContact |
| LEU 2 | NTc.Cm32 | GLU 283 | 7.39x38 | VdWContact |
| ALA 3 | NTc.Cm31 | GLN 280 | 7.36x35 | Hydrophobic |
| ALA 3 | NTc.Cm31 | GLN 280 | 7.36x35 | VdWContact |
| ALA 3 | NTc.Cm31 | GLU 283 | 7.39x38 | HBDonor |
| ALA 3 | NTc.Cm31 | GLU 283 | 7.39x38 | Hydrophobic |
| ALA 3 | NTc.Cm31 | GLU 283 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm30 | TYR 37 | 1.39x39 | Hydrophobic |
| ALA 4 | NTc.Cm30 | TRP 86 | 2.60x60 | Hydrophobic |
| ALA 4 | NTc.Cm30 | TYR 89 | 2.63x63 | Hydrophobic |
| ALA 4 | NTc.Cm30 | ALA 90 | 2.64x64 | Hydrophobic |
| ASP 5 | NTc.Cm29 | TYR 89 | 2.63x63 | HBAcceptor |
| ASP 5 | NTc.Cm29 | TYR 89 | 2.63x63 | Hydrophobic |
| ASP 5 | NTc.Cm29 | TYR 89 | 2.63x63 | VdWContact |
| ASP 5 | NTc.Cm29 | CYS 178 | 45.50x50 | VdWContact |
| ASP 5 | NTc.Cm29 | SER 179 | 45.51x51 | VdWContact |
| THR 6 | NTc.Cm28 | VAL 25 | 1.27x27 | Hydrophobic |
| THR 6 | NTc.Cm28 | LYS 26 | 1.28x28 | Hydrophobic |
| THR 6 | NTc.Cm28 | LYS 26 | 1.28x28 | VdWContact |
| THR 6 | NTc.Cm28 | ASP 276 | 7.32x31 | Hydrophobic |
| THR 6 | NTc.Cm28 | GLN 280 | 7.36x35 | HBAcceptor |
| THR 6 | NTc.Cm28 | GLN 280 | 7.36x35 | VdWContact |
| PRO 7 | NTc.Cm27 | LYS 22 | 1.24x24 | Hydrophobic |
| PRO 7 | NTc.Cm27 | LYS 22 | 1.24x24 | VdWContact |
| PRO 7 | NTc.Cm27 | LYS 26 | 1.28x28 | VdWContact |
| THR 8 | NTc.Cm26 | LYS 22 | 1.24x24 | HBAcceptor |
| THR 8 | NTc.Cm26 | LYS 22 | 1.24x24 | VdWContact |
| THR 8 | NTc.Cm26 | LYS 26 | 1.28x28 | Hydrophobic |
| THR 8 | NTc.Cm26 | LYS 26 | 1.28x28 | VdWContact |
| THR 8 | NTc.Cm26 | GLU 172 | - | HBDonor |
| THR 8 | NTc.Cm26 | GLU 172 | - | Hydrophobic |
| THR 8 | NTc.Cm26 | GLU 172 | - | VdWContact |
| THR 8 | NTc.Cm26 | THR 177 | - | Hydrophobic |
| ALA 9 | NTc.Cm25 | PRO 19 | - | Hydrophobic |
| ALA 9 | NTc.Cm25 | PRO 19 | - | VdWContact |
| ALA 9 | NTc.Cm25 | CYS 20 | - | VdWContact |
| CYS 10 | NTc.Cm24 | CYS 20 | - | HBAcceptor |
| CYS 10 | NTc.Cm24 | CYS 20 | - | HBDonor |
| CYS 10 | NTc.Cm24 | CYS 20 | - | VdWContact |
| CYS 10 | NTc.Cm24 | LYS 22 | 1.24x24 | Anionic |
| CYS 10 | NTc.Cm24 | LYS 22 | 1.24x24 | VdWContact |
| PHE 12 | NTc.Cm22 | CYS 20 | - | Hydrophobic |
| PHE 12 | NTc.Cm22 | CYS 20 | - | VdWContact |
| PHE 12 | NTc.Cm22 | ASN 267 | - | VdWContact |
| PHE 12 | NTc.Cm22 | CYS 269 | 7.25x24 | Hydrophobic |
| PHE 12 | NTc.Cm22 | SER 272 | 7.28x27 | VdWContact |
| SER 13 | NTc.Cm21 | THR 16 | - | HBDonor |
| SER 13 | NTc.Cm21 | THR 16 | - | VdWContact |
| ILE 19 | NTc.Cm15 | TYR 14 | - | Hydrophobic |
| ILE 19 | NTc.Cm15 | TYR 14 | - | VdWContact |
| ASP 26 | NTc.Cm7 | LYS 171 | - | Anionic |
| PHE 28 | NTc.Cm5 | GLU 172 | - | Hydrophobic |
| GLU 29 | NTc.Cm4 | ARG 168 | - | Anionic |
| GLU 29 | NTc.Cm4 | ARG 168 | - | HBAcceptor |
| GLU 29 | NTc.Cm4 | ARG 168 | - | VdWContact |
| GLU 29 | NTc.Cm4 | GLN 170 | - | HBAcceptor |
| GLU 29 | NTc.Cm4 | GLN 170 | - | VdWContact |
| GLU 29 | NTc.Cm4 | HIS 181 | - | HBAcceptor |
| GLU 29 | NTc.Cm4 | HIS 181 | - | Hydrophobic |
| GLU 29 | NTc.Cm4 | HIS 181 | - | VdWContact |
| SER 32 | NTc.Cm1 | SER 180 | 45.52x52 | HBDonor |
| SER 32 | NTc.Cm1 | SER 180 | 45.52x52 | VdWContact |
| SER 32 | NTc.Cm1 | HIS 181 | - | HBDonor |
| SER 32 | NTc.Cm1 | HIS 181 | - | VdWContact |
| SER 32 | NTc.Cm1 | PHE 182 | - | HBAcceptor |
| SER 32 | NTc.Cm1 | PHE 182 | - | VdWContact |
| SER 32 | NTc.Cm1 | TYR 187 | 5.31x32 | VdWContact |
| SER 32 | NTc.Cm1 | LYS 191 | 5.35x36 | VdWContact |
| GLN 33 | CX.1 | LYS 191 | 5.35x36 | HBAcceptor |
| GLN 33 | CX.1 | LYS 191 | 5.35x36 | VdWContact |
| CYS 34 | CX.5 | TYR 187 | 5.31x32 | VdWContact |
| CYS 34 | CX.5 | LYS 191 | 5.35x36 | HBAcceptor |
| CYS 34 | CX.5 | LYS 191 | 5.35x36 | VdWContact |
| SER 35 | cxb1.1 | GLN 261 | 6.61x61 | VdWContact |
| SER 35 | cxb1.1 | ASN 267 | - | HBDonor |
| SER 35 | cxb1.1 | ASN 267 | - | VdWContact |
| LYS 36 | cxb1.2 | ASN 267 | - | VdWContact |
| PRO 37 | cxb1.5 | TYR 184 | - | Hydrophobic |
| PRO 37 | cxb1.5 | TYR 187 | 5.31x32 | Hydrophobic |
| PRO 37 | cxb1.5 | TYR 187 | 5.31x32 | VdWContact |
| ILE 40 | cxb1.8 | PRO 19 | - | Hydrophobic |
| ARG 47 | B1.2 | ASP 11 | - | Cationic |
| ARG 47 | B1.2 | ASP 11 | - | HBDonor |
| ARG 47 | B1.2 | ASP 11 | - | VdWContact |
| GLN 48 | B1.3 | PRO 19 | - | Hydrophobic |
| GLN 48 | B1.3 | GLN 21 | - | HBAcceptor |
| GLN 48 | B1.3 | GLN 21 | - | VdWContact |
| VAL 49 | B1.4 | TYR 14 | - | Hydrophobic |
| CYS 50 | B1.5 | SER 17 | - | HBDonor |
| CYS 50 | B1.5 | SER 17 | - | VdWContact |
| CYS 50 | B1.5 | PRO 19 | - | VdWContact |
| PRO 53 | b1b2.4 | TYR 184 | - | Hydrophobic |
