Predicted complex interactions
CCL4_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 94
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm33 | TRP 86 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm33 | TRP 86 | 2.60x60 | VdWContact |
| ALA 1 | NTc.Cm33 | THR 105 | 3.29x29 | VdWContact |
| PRO 2 | NTc.Cm32 | TRP 86 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TRP 86 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 108 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 108 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm32 | GLU 283 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm32 | MET 287 | 7.43x42 | Hydrophobic |
| MET 3 | NTc.Cm31 | ILE 198 | 5.42x43 | Hydrophobic |
| MET 3 | NTc.Cm31 | LEU 255 | 6.55x55 | Hydrophobic |
| MET 3 | NTc.Cm31 | LEU 255 | 6.55x55 | VdWContact |
| MET 3 | NTc.Cm31 | MET 279 | 7.35x34 | Hydrophobic |
| MET 3 | NTc.Cm31 | GLU 283 | 7.39x38 | HBDonor |
| MET 3 | NTc.Cm31 | GLU 283 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm30 | GLN 280 | 7.36x35 | VdWContact |
| GLY 4 | NTc.Cm30 | GLU 283 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm30 | GLU 283 | 7.39x38 | VdWContact |
| SER 5 | NTc.Cm29 | TYR 37 | 1.39x39 | VdWContact |
| SER 5 | NTc.Cm29 | TRP 86 | 2.60x60 | VdWContact |
| ASP 6 | NTc.Cm28 | TYR 89 | 2.63x63 | HBAcceptor |
| ASP 6 | NTc.Cm28 | TYR 89 | 2.63x63 | Hydrophobic |
| ASP 6 | NTc.Cm28 | TYR 89 | 2.63x63 | VdWContact |
| ASP 6 | NTc.Cm28 | SER 179 | 45.51x51 | VdWContact |
| PRO 7 | NTc.Cm27 | VAL 25 | 1.27x27 | Hydrophobic |
| PRO 8 | NTc.Cm26 | LYS 22 | 1.24x24 | Hydrophobic |
| PRO 8 | NTc.Cm26 | LYS 22 | 1.24x24 | VdWContact |
| THR 9 | NTc.Cm25 | LYS 22 | 1.24x24 | HBAcceptor |
| THR 9 | NTc.Cm25 | LYS 22 | 1.24x24 | VdWContact |
| THR 9 | NTc.Cm25 | GLU 172 | - | HBDonor |
| THR 9 | NTc.Cm25 | GLU 172 | - | VdWContact |
| THR 9 | NTc.Cm25 | THR 177 | - | Hydrophobic |
| ALA 10 | NTc.Cm24 | PRO 19 | - | Hydrophobic |
| ALA 10 | NTc.Cm24 | PRO 19 | - | VdWContact |
| ALA 10 | NTc.Cm24 | CYS 20 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 20 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 20 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 20 | - | VdWContact |
| CYS 11 | NTc.Cm23 | LYS 22 | 1.24x24 | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 20 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 20 | - | VdWContact |
| PHE 13 | NTc.Cm21 | ASN 267 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 269 | 7.25x24 | Hydrophobic |
| PHE 13 | NTc.Cm21 | SER 272 | 7.28x27 | VdWContact |
| SER 14 | NTc.Cm20 | THR 16 | - | HBDonor |
| SER 14 | NTc.Cm20 | THR 16 | - | VdWContact |
| LEU 20 | NTc.Cm14 | TYR 14 | - | Hydrophobic |
| LEU 20 | NTc.Cm14 | TYR 14 | - | VdWContact |
| ASP 27 | NTc.Cm7 | LYS 171 | - | Anionic |
| TYR 29 | NTc.Cm5 | GLU 172 | - | Hydrophobic |
| GLU 30 | NTc.Cm4 | ARG 168 | - | Anionic |
| GLU 30 | NTc.Cm4 | ARG 168 | - | HBAcceptor |
| GLU 30 | NTc.Cm4 | ARG 168 | - | VdWContact |
| GLU 30 | NTc.Cm4 | GLN 170 | - | HBAcceptor |
| GLU 30 | NTc.Cm4 | GLN 170 | - | VdWContact |
| GLU 30 | NTc.Cm4 | HIS 181 | - | Hydrophobic |
| GLU 30 | NTc.Cm4 | HIS 181 | - | VdWContact |
| SER 33 | NTc.Cm1 | SER 180 | 45.52x52 | HBDonor |
| SER 33 | NTc.Cm1 | SER 180 | 45.52x52 | VdWContact |
| SER 33 | NTc.Cm1 | HIS 181 | - | VdWContact |
| SER 33 | NTc.Cm1 | PHE 182 | - | HBAcceptor |
| SER 33 | NTc.Cm1 | PHE 182 | - | VdWContact |
| SER 33 | NTc.Cm1 | TYR 187 | 5.31x32 | VdWContact |
| SER 33 | NTc.Cm1 | LYS 191 | 5.35x36 | VdWContact |
| LEU 34 | CX.1 | LYS 191 | 5.35x36 | HBAcceptor |
| LEU 34 | CX.1 | LYS 191 | 5.35x36 | VdWContact |
| CYS 35 | CX.5 | TYR 187 | 5.31x32 | HBAcceptor |
| CYS 35 | CX.5 | TYR 187 | 5.31x32 | VdWContact |
| CYS 35 | CX.5 | LYS 191 | 5.35x36 | HBAcceptor |
| CYS 35 | CX.5 | LYS 191 | 5.35x36 | VdWContact |
| SER 36 | cxb1.1 | GLN 188 | 5.32x33 | HBAcceptor |
| SER 36 | cxb1.1 | GLN 188 | 5.32x33 | VdWContact |
| SER 36 | cxb1.1 | ASN 267 | - | HBDonor |
| SER 36 | cxb1.1 | ASN 267 | - | VdWContact |
| PRO 38 | cxb1.5 | TYR 184 | - | Hydrophobic |
| PRO 38 | cxb1.5 | TYR 187 | 5.31x32 | Hydrophobic |
| PRO 38 | cxb1.5 | TYR 187 | 5.31x32 | VdWContact |
| VAL 41 | cxb1.8 | PRO 19 | - | Hydrophobic |
| ARG 46 | cxb1.16 | ILE 9 | - | VdWContact |
| ARG 46 | cxb1.16 | ASP 11 | - | Cationic |
| ARG 46 | cxb1.16 | ASP 11 | - | HBDonor |
| ARG 46 | cxb1.16 | ASP 11 | - | VdWContact |
| LYS 48 | B1.2 | TYR 15 | - | VdWContact |
| LYS 48 | B1.2 | GLU 18 | - | Cationic |
| LYS 48 | B1.2 | GLU 18 | - | HBDonor |
| LYS 48 | B1.2 | GLU 18 | - | VdWContact |
| GLN 49 | B1.3 | PRO 19 | - | Hydrophobic |
| GLN 49 | B1.3 | GLN 21 | - | HBAcceptor |
| GLN 49 | B1.3 | GLN 21 | - | VdWContact |
| VAL 50 | B1.4 | TYR 14 | - | Hydrophobic |
| CYS 51 | B1.5 | SER 17 | - | HBDonor |
| CYS 51 | B1.5 | SER 17 | - | VdWContact |
| CYS 51 | B1.5 | PRO 19 | - | VdWContact |
| PRO 54 | b1b2.4 | TYR 184 | - | Hydrophobic |
