Predicted complex interactions
CCL5_HUMAN + CCR5
SUMMARY
- Chemokine
- CCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 100
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm32 | TRP 86 | 2.60x60 | VdWContact |
| SER 1 | NTc.Cm32 | TYR 108 | 3.32x32 | VdWContact |
| SER 1 | NTc.Cm32 | GLU 283 | 7.39x38 | Cationic |
| SER 1 | NTc.Cm32 | GLU 283 | 7.39x38 | VdWContact |
| SER 1 | NTc.Cm32 | MET 287 | 7.43x42 | VdWContact |
| PRO 2 | NTc.Cm31 | TRP 86 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm31 | TYR 108 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm31 | TYR 108 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm31 | PHE 109 | 3.33x33 | Hydrophobic |
| TYR 3 | NTc.Cm30 | PHE 109 | 3.33x33 | Hydrophobic |
| TYR 3 | NTc.Cm30 | ILE 198 | 5.42x43 | Hydrophobic |
| TYR 3 | NTc.Cm30 | ILE 198 | 5.42x43 | VdWContact |
| TYR 3 | NTc.Cm30 | TYR 251 | 6.51x51 | Hydrophobic |
| TYR 3 | NTc.Cm30 | LEU 255 | 6.55x55 | Hydrophobic |
| TYR 3 | NTc.Cm30 | MET 279 | 7.35x34 | Hydrophobic |
| TYR 3 | NTc.Cm30 | GLU 283 | 7.39x38 | HBDonor |
| TYR 3 | NTc.Cm30 | GLU 283 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm29 | TYR 37 | 1.39x39 | HBDonor |
| SER 4 | NTc.Cm29 | TYR 37 | 1.39x39 | VdWContact |
| SER 4 | NTc.Cm29 | GLN 280 | 7.36x35 | HBAcceptor |
| SER 4 | NTc.Cm29 | GLN 280 | 7.36x35 | VdWContact |
| SER 4 | NTc.Cm29 | GLU 283 | 7.39x38 | HBDonor |
| SER 4 | NTc.Cm29 | GLU 283 | 7.39x38 | VdWContact |
| SER 5 | NTc.Cm28 | TRP 86 | 2.60x60 | HBDonor |
| SER 5 | NTc.Cm28 | TRP 86 | 2.60x60 | VdWContact |
| SER 5 | NTc.Cm28 | ALA 90 | 2.64x64 | VdWContact |
| THR 7 | NTc.Cm26 | VAL 25 | 1.27x27 | Hydrophobic |
| THR 7 | NTc.Cm26 | LYS 26 | 1.28x28 | Hydrophobic |
| THR 7 | NTc.Cm26 | LYS 26 | 1.28x28 | VdWContact |
| THR 7 | NTc.Cm26 | ALA 29 | 1.31x31 | Hydrophobic |
| THR 8 | NTc.Cm25 | GLU 172 | - | VdWContact |
| THR 8 | NTc.Cm25 | THR 177 | - | Hydrophobic |
| THR 8 | NTc.Cm25 | THR 177 | - | VdWContact |
| PRO 9 | NTc.Cm24 | PRO 19 | - | Hydrophobic |
| PRO 9 | NTc.Cm24 | PRO 19 | - | VdWContact |
| PRO 9 | NTc.Cm24 | CYS 20 | - | VdWContact |
| PRO 9 | NTc.Cm24 | GLN 21 | - | VdWContact |
| PRO 9 | NTc.Cm24 | GLU 172 | - | VdWContact |
| CYS 10 | NTc.Cm23 | CYS 20 | - | HBAcceptor |
| CYS 10 | NTc.Cm23 | CYS 20 | - | HBDonor |
| CYS 10 | NTc.Cm23 | CYS 20 | - | VdWContact |
| CYS 10 | NTc.Cm23 | LYS 22 | 1.24x24 | Anionic |
| CYS 10 | NTc.Cm23 | LYS 22 | 1.24x24 | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 20 | - | Hydrophobic |
| PHE 12 | NTc.Cm21 | ASN 267 | - | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 269 | 7.25x24 | Hydrophobic |
| PHE 12 | NTc.Cm21 | SER 272 | 7.28x27 | VdWContact |
| ILE 15 | NTc.Cm18 | ILE 12 | - | Hydrophobic |
| LEU 19 | NTc.Cm14 | ILE 12 | - | Hydrophobic |
| LEU 19 | NTc.Cm14 | TYR 14 | - | Hydrophobic |
| LEU 19 | NTc.Cm14 | TYR 14 | - | VdWContact |
| PRO 20 | NTc.Cm13 | ILE 12 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | ILE 12 | - | VdWContact |
| GLU 26 | NTc.Cm7 | LYS 171 | - | Anionic |
| GLU 26 | NTc.Cm7 | GLY 173 | - | VdWContact |
| PHE 28 | NTc.Cm5 | GLU 172 | - | Hydrophobic |
| PHE 28 | NTc.Cm5 | GLU 172 | - | VdWContact |
| TYR 29 | NTc.Cm4 | ARG 168 | - | VdWContact |
| TYR 29 | NTc.Cm4 | GLN 170 | - | HBAcceptor |
| TYR 29 | NTc.Cm4 | GLN 170 | - | VdWContact |
| TYR 29 | NTc.Cm4 | HIS 181 | - | Hydrophobic |
| TYR 29 | NTc.Cm4 | HIS 181 | - | VdWContact |
| THR 30 | NTc.Cm3 | HIS 181 | - | HBAcceptor |
| THR 30 | NTc.Cm3 | HIS 181 | - | VdWContact |
| GLY 32 | NTc.Cm1 | SER 180 | 45.52x52 | HBDonor |
| GLY 32 | NTc.Cm1 | SER 180 | 45.52x52 | VdWContact |
| GLY 32 | NTc.Cm1 | TYR 187 | 5.31x32 | VdWContact |
| GLY 32 | NTc.Cm1 | LYS 191 | 5.35x36 | VdWContact |
| LYS 33 | CX.1 | LYS 191 | 5.35x36 | HBAcceptor |
| LYS 33 | CX.1 | LYS 191 | 5.35x36 | VdWContact |
| LYS 33 | CX.1 | ASN 258 | 6.58x58 | HBAcceptor |
| LYS 33 | CX.1 | ASN 258 | 6.58x58 | VdWContact |
| LYS 33 | CX.1 | ASP 276 | 7.32x31 | Cationic |
| LYS 33 | CX.1 | ASP 276 | 7.32x31 | HBDonor |
| LYS 33 | CX.1 | ASP 276 | 7.32x31 | VdWContact |
| CYS 34 | CX.5 | TYR 187 | 5.31x32 | HBAcceptor |
| CYS 34 | CX.5 | TYR 187 | 5.31x32 | VdWContact |
| CYS 34 | CX.5 | LYS 191 | 5.35x36 | HBAcceptor |
| CYS 34 | CX.5 | LYS 191 | 5.35x36 | VdWContact |
| SER 35 | cxb1.1 | GLN 188 | 5.32x33 | HBAcceptor |
| SER 35 | cxb1.1 | GLN 188 | 5.32x33 | VdWContact |
| SER 35 | cxb1.1 | GLN 261 | 6.61x61 | VdWContact |
| SER 35 | cxb1.1 | ASN 267 | - | HBDonor |
| SER 35 | cxb1.1 | ASN 267 | - | VdWContact |
| PRO 37 | cxb1.5 | TYR 184 | - | Hydrophobic |
| PRO 37 | cxb1.5 | TYR 187 | 5.31x32 | Hydrophobic |
| PRO 37 | cxb1.5 | TYR 187 | 5.31x32 | VdWContact |
| VAL 40 | cxb1.8 | PRO 19 | - | Hydrophobic |
| THR 43 | cxb1.14 | TYR 14 | - | Hydrophobic |
| ARG 47 | B1.2 | TYR 14 | - | VdWContact |
| GLN 48 | B1.3 | PRO 19 | - | Hydrophobic |
| GLN 48 | B1.3 | GLN 21 | - | HBAcceptor |
| GLN 48 | B1.3 | GLN 21 | - | VdWContact |
| VAL 49 | B1.4 | TYR 14 | - | Hydrophobic |
| VAL 49 | B1.4 | TYR 14 | - | VdWContact |
| CYS 50 | B1.5 | SER 17 | - | HBDonor |
| CYS 50 | B1.5 | SER 17 | - | VdWContact |
| CYS 50 | B1.5 | PRO 19 | - | VdWContact |
| PRO 53 | b1b2.4 | TYR 184 | - | Hydrophobic |
| GLU 54 | b1b2.6 | TYR 184 | - | Hydrophobic |
