Predicted complex interactions
CX3CL1_HUMAN + CCR5
SUMMARY
- Chemokine
- CX3CL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 91
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm37 | PHE 109 | 3.33x33 | VdWContact |
| GLN 1 | NTc.Cm37 | SER 179 | 45.51x51 | VdWContact |
| GLN 1 | NTc.Cm37 | SER 180 | 45.52x52 | HBAcceptor |
| GLN 1 | NTc.Cm37 | SER 180 | 45.52x52 | VdWContact |
| HIS 2 | NTc.Cm36 | TYR 37 | 1.39x39 | Hydrophobic |
| HIS 2 | NTc.Cm36 | TYR 37 | 1.39x39 | VdWContact |
| HIS 2 | NTc.Cm36 | TRP 86 | 2.60x60 | Hydrophobic |
| HIS 2 | NTc.Cm36 | TRP 86 | 2.60x60 | PiStacking |
| HIS 2 | NTc.Cm36 | TYR 108 | 3.32x32 | Hydrophobic |
| HIS 2 | NTc.Cm36 | GLU 283 | 7.39x38 | VdWContact |
| HIS 2 | NTc.Cm36 | MET 287 | 7.43x42 | Hydrophobic |
| HIS 2 | NTc.Cm36 | MET 287 | 7.43x42 | VdWContact |
| HIS 3 | NTc.Cm35 | LEU 255 | 6.55x55 | Hydrophobic |
| HIS 3 | NTc.Cm35 | MET 279 | 7.35x34 | Hydrophobic |
| HIS 3 | NTc.Cm35 | GLU 283 | 7.39x38 | HBDonor |
| HIS 3 | NTc.Cm35 | GLU 283 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm34 | GLU 283 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm34 | GLU 283 | 7.39x38 | VdWContact |
| VAL 5 | NTc.Cm33 | LEU 33 | 1.35x35 | Hydrophobic |
| VAL 5 | NTc.Cm33 | TYR 37 | 1.39x39 | Hydrophobic |
| VAL 5 | NTc.Cm33 | TRP 86 | 2.60x60 | Hydrophobic |
| VAL 5 | NTc.Cm33 | TYR 89 | 2.63x63 | Hydrophobic |
| VAL 5 | NTc.Cm33 | ALA 90 | 2.64x64 | Hydrophobic |
| VAL 5 | NTc.Cm33 | ALA 90 | 2.64x64 | VdWContact |
| THR 6 | NTc.Cm32 | LYS 26 | 1.28x28 | VdWContact |
| LYS 7 | NTc.Cm31 | TYR 89 | 2.63x63 | HBDonor |
| LYS 7 | NTc.Cm31 | TYR 89 | 2.63x63 | Hydrophobic |
| LYS 7 | NTc.Cm31 | TYR 89 | 2.63x63 | VdWContact |
| LYS 7 | NTc.Cm31 | ALA 90 | 2.64x64 | VdWContact |
| LYS 7 | NTc.Cm31 | ALA 92 | 2.66x66 | VdWContact |
| LYS 7 | NTc.Cm31 | THR 177 | - | Hydrophobic |
| LYS 7 | NTc.Cm31 | THR 177 | - | VdWContact |
| CYS 8 | NTc.Cm30 | LYS 26 | 1.28x28 | VdWContact |
| ASN 9 | NTc.Cm29 | GLN 21 | - | VdWContact |
| ASN 9 | NTc.Cm29 | LYS 22 | 1.24x24 | HBAcceptor |
| ASN 9 | NTc.Cm29 | LYS 22 | 1.24x24 | VdWContact |
| ASN 9 | NTc.Cm29 | ILE 23 | 1.25x25 | Hydrophobic |
| ASN 9 | NTc.Cm29 | LYS 26 | 1.28x28 | VdWContact |
| ILE 10 | NTc.Cm28 | PRO 19 | - | Hydrophobic |
| ILE 10 | NTc.Cm28 | PRO 19 | - | VdWContact |
| ILE 10 | NTc.Cm28 | CYS 20 | - | VdWContact |
| ILE 10 | NTc.Cm28 | GLN 21 | - | VdWContact |
| THR 11 | NTc.Cm27 | CYS 20 | - | HBAcceptor |
| THR 11 | NTc.Cm27 | CYS 20 | - | HBDonor |
| THR 11 | NTc.Cm27 | CYS 20 | - | VdWContact |
| THR 11 | NTc.Cm27 | LYS 22 | 1.24x24 | Hydrophobic |
| THR 11 | NTc.Cm27 | LYS 22 | 1.24x24 | VdWContact |
| SER 13 | NTc.Cm25 | ASN 267 | - | HBDonor |
| SER 13 | NTc.Cm25 | ASN 267 | - | VdWContact |
| LYS 14 | NTc.Cm24 | THR 16 | - | VdWContact |
| THR 16 | NTc.Cm22 | TYR 14 | - | VdWContact |
| THR 16 | NTc.Cm22 | SER 17 | - | VdWContact |
| LYS 18 | NTc.Cm20 | TYR 14 | - | HBAcceptor |
| LYS 18 | NTc.Cm20 | TYR 14 | - | VdWContact |
| ILE 19 | NTc.Cm19 | TYR 14 | - | Hydrophobic |
| ILE 19 | NTc.Cm19 | TYR 14 | - | VdWContact |
| GLN 31 | NTc.Cm7 | GLU 172 | - | VdWContact |
| ALA 32 | NTc.Cm6 | GLN 170 | - | VdWContact |
| ALA 32 | NTc.Cm6 | GLU 172 | - | VdWContact |
| ALA 32 | NTc.Cm6 | HIS 181 | - | HBAcceptor |
| ALA 32 | NTc.Cm6 | HIS 181 | - | Hydrophobic |
| ALA 32 | NTc.Cm6 | HIS 181 | - | VdWContact |
| SER 33 | NTc.Cm5 | GLU 172 | - | HBDonor |
| SER 33 | NTc.Cm5 | GLU 172 | - | VdWContact |
| SER 33 | NTc.Cm5 | SER 179 | 45.51x51 | VdWContact |
| GLY 35 | NTc.Cm3 | TYR 187 | 5.31x32 | VdWContact |
| LYS 36 | NTc.Cm2 | TYR 187 | 5.31x32 | Hydrophobic |
| ARG 37 | NTc.Cm1 | TYR 184 | - | Hydrophobic |
| ARG 37 | NTc.Cm1 | TYR 184 | - | VdWContact |
| ILE 40 | CX.3 | PRO 19 | - | Hydrophobic |
| ARG 47 | cxb1.8 | TYR 15 | - | CationPi |
| ARG 47 | cxb1.8 | TYR 15 | - | VdWContact |
| ARG 47 | cxb1.8 | GLU 18 | - | Cationic |
| ARG 47 | cxb1.8 | GLU 18 | - | HBDonor |
| ARG 47 | cxb1.8 | GLU 18 | - | VdWContact |
| LEU 48 | cxb1.10 | PRO 19 | - | Hydrophobic |
| LEU 48 | cxb1.10 | PRO 19 | - | VdWContact |
| PHE 49 | cxb1.11 | TYR 14 | - | Hydrophobic |
| PHE 49 | cxb1.11 | TYR 14 | - | VdWContact |
| PHE 49 | cxb1.11 | GLU 18 | - | Hydrophobic |
| CYS 50 | cxb1.14 | SER 17 | - | HBDonor |
| CYS 50 | cxb1.14 | SER 17 | - | VdWContact |
| CYS 50 | cxb1.14 | PRO 19 | - | VdWContact |
| ASP 52 | cxb1.16 | TYR 184 | - | VdWContact |
| PRO 53 | B1.1 | TYR 184 | - | Hydrophobic |
| PRO 53 | B1.1 | TYR 184 | - | VdWContact |
| LYS 54 | B1.2 | TYR 184 | - | CationPi |
| LYS 54 | B1.2 | TYR 184 | - | HBDonor |
| LYS 54 | B1.2 | TYR 184 | - | Hydrophobic |
| LYS 54 | B1.2 | TYR 184 | - | VdWContact |
| LYS 54 | B1.2 | SER 185 | - | VdWContact |
