Predicted complex interactions
CXCL1_HUMAN + CCR5
SUMMARY
- Chemokine
- CXCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 74
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm42 | TRP 86 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm42 | TRP 86 | 2.60x60 | VdWContact |
| ALA 1 | NTc.Cm42 | TYR 108 | 3.32x32 | CationPi |
| ALA 1 | NTc.Cm42 | TYR 108 | 3.32x32 | Hydrophobic |
| ALA 1 | NTc.Cm42 | TYR 108 | 3.32x32 | VdWContact |
| ALA 1 | NTc.Cm42 | GLU 283 | 7.39x38 | Cationic |
| ALA 1 | NTc.Cm42 | GLU 283 | 7.39x38 | HBDonor |
| ALA 1 | NTc.Cm42 | GLU 283 | 7.39x38 | VdWContact |
| SER 2 | NTc.Cm41 | TRP 86 | 2.60x60 | VdWContact |
| SER 2 | NTc.Cm41 | TYR 89 | 2.63x63 | VdWContact |
| VAL 3 | NTc.Cm40 | GLU 283 | 7.39x38 | HBDonor |
| VAL 3 | NTc.Cm40 | GLU 283 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm39 | TYR 89 | 2.63x63 | Hydrophobic |
| ALA 4 | NTc.Cm39 | TYR 89 | 2.63x63 | VdWContact |
| THR 5 | NTc.Cm38 | ASP 276 | 7.32x31 | Hydrophobic |
| THR 5 | NTc.Cm38 | ASP 276 | 7.32x31 | VdWContact |
| THR 5 | NTc.Cm38 | GLN 280 | 7.36x35 | HBAcceptor |
| THR 5 | NTc.Cm38 | GLN 280 | 7.36x35 | VdWContact |
| GLU 6 | NTc.Cm37 | GLU 172 | - | VdWContact |
| GLU 6 | NTc.Cm37 | THR 177 | - | HBAcceptor |
| GLU 6 | NTc.Cm37 | THR 177 | - | Hydrophobic |
| GLU 6 | NTc.Cm37 | THR 177 | - | VdWContact |
| GLU 6 | NTc.Cm37 | SER 179 | 45.51x51 | HBAcceptor |
| GLU 6 | NTc.Cm37 | SER 179 | 45.51x51 | VdWContact |
| LEU 7 | NTc.Cm36 | LYS 22 | 1.24x24 | Hydrophobic |
| LEU 7 | NTc.Cm36 | LYS 22 | 1.24x24 | VdWContact |
| LEU 7 | NTc.Cm36 | LYS 26 | 1.28x28 | Hydrophobic |
| LEU 7 | NTc.Cm36 | LYS 26 | 1.28x28 | VdWContact |
| ARG 8 | NTc.Cm35 | LYS 22 | 1.24x24 | VdWContact |
| ARG 8 | NTc.Cm35 | ASN 258 | 6.58x58 | HBDonor |
| ARG 8 | NTc.Cm35 | ASN 258 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm35 | GLN 261 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm35 | SER 272 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm35 | LEU 275 | 7.31x30 | VdWContact |
| ARG 8 | NTc.Cm35 | ASP 276 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm35 | ASP 276 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm35 | ASP 276 | 7.32x31 | VdWContact |
| GLN 10 | NTc.Cm33 | PRO 19 | - | Hydrophobic |
| GLN 10 | NTc.Cm33 | PRO 19 | - | VdWContact |
| GLN 10 | NTc.Cm33 | CYS 20 | - | HBAcceptor |
| GLN 10 | NTc.Cm33 | CYS 20 | - | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 20 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | ASN 267 | - | VdWContact |
| LEU 12 | NTc.Cm31 | ASN 268 | 7.24x23 | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 269 | 7.25x24 | Hydrophobic |
| LEU 12 | NTc.Cm31 | CYS 269 | 7.25x24 | VdWContact |
| GLN 13 | NTc.Cm30 | THR 16 | - | VdWContact |
| LEU 15 | NTc.Cm28 | ILE 12 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | TYR 14 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | TYR 14 | - | VdWContact |
| LEU 15 | NTc.Cm28 | SER 17 | - | VdWContact |
| ILE 18 | NTc.Cm25 | TYR 14 | - | Hydrophobic |
| ILE 18 | NTc.Cm25 | TYR 14 | - | VdWContact |
| PRO 31 | NTc.Cm12 | TYR 184 | - | Hydrophobic |
| PRO 31 | NTc.Cm12 | TYR 184 | - | VdWContact |
| PRO 33 | NTc.Cm10 | HIS 181 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | HIS 181 | - | VdWContact |
| PRO 33 | NTc.Cm10 | TYR 187 | 5.31x32 | VdWContact |
| HIS 34 | NTc.Cm9 | SER 179 | 45.51x51 | HBDonor |
| HIS 34 | NTc.Cm9 | SER 179 | 45.51x51 | VdWContact |
| ALA 36 | NTc.Cm7 | TYR 184 | - | Hydrophobic |
| ALA 36 | NTc.Cm7 | TYR 184 | - | VdWContact |
| ALA 36 | NTc.Cm7 | TYR 187 | 5.31x32 | Hydrophobic |
| ALA 36 | NTc.Cm7 | TYR 187 | 5.31x32 | VdWContact |
| GLN 37 | NTc.Cm6 | TYR 184 | - | VdWContact |
| ILE 41 | NTc.Cm2 | PRO 19 | - | Hydrophobic |
| LEU 44 | CX.4 | TYR 14 | - | Hydrophobic |
| ARG 48 | cxb1.5 | TYR 15 | - | VdWContact |
| LYS 49 | cxb1.6 | GLU 18 | - | VdWContact |
| LYS 49 | cxb1.6 | PRO 19 | - | Hydrophobic |
| ALA 50 | cxb1.8 | TYR 14 | - | Hydrophobic |
| ALA 50 | cxb1.8 | SER 17 | - | VdWContact |
| CYS 51 | cxb1.10 | SER 17 | - | HBDonor |
| CYS 51 | cxb1.10 | SER 17 | - | VdWContact |
