Predicted complex interactions
CXCL11_HUMAN + CCR5
SUMMARY
- Chemokine
- CXCL11_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 84
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PHE 1 | NTc.Cm29 | TYR 108 | 3.32x32 | Hydrophobic |
| PHE 1 | NTc.Cm29 | TYR 108 | 3.32x32 | PiStacking |
| PHE 1 | NTc.Cm29 | TYR 108 | 3.32x32 | VdWContact |
| PHE 1 | NTc.Cm29 | PHE 109 | 3.33x33 | Hydrophobic |
| PHE 1 | NTc.Cm29 | PHE 112 | 3.36x36 | Hydrophobic |
| PHE 1 | NTc.Cm29 | PHE 112 | 3.36x36 | PiStacking |
| PHE 1 | NTc.Cm29 | PHE 112 | 3.36x36 | VdWContact |
| PHE 1 | NTc.Cm29 | ILE 198 | 5.42x43 | Hydrophobic |
| PHE 1 | NTc.Cm29 | TRP 248 | 6.48x48 | Hydrophobic |
| PHE 1 | NTc.Cm29 | TRP 248 | 6.48x48 | VdWContact |
| PHE 1 | NTc.Cm29 | TYR 251 | 6.51x51 | Hydrophobic |
| PHE 1 | NTc.Cm29 | TYR 251 | 6.51x51 | PiStacking |
| PHE 1 | NTc.Cm29 | GLU 283 | 7.39x38 | Cationic |
| PHE 1 | NTc.Cm29 | GLU 283 | 7.39x38 | Hydrophobic |
| PHE 1 | NTc.Cm29 | GLU 283 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm28 | TRP 86 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm28 | THR 105 | 3.29x29 | Hydrophobic |
| PRO 2 | NTc.Cm28 | PHE 109 | 3.33x33 | Hydrophobic |
| MET 3 | NTc.Cm27 | TRP 86 | 2.60x60 | Hydrophobic |
| MET 3 | NTc.Cm27 | TRP 86 | 2.60x60 | VdWContact |
| MET 3 | NTc.Cm27 | TYR 89 | 2.63x63 | Hydrophobic |
| MET 3 | NTc.Cm27 | TYR 89 | 2.63x63 | VdWContact |
| MET 3 | NTc.Cm27 | TRP 94 | 23.50x50 | Hydrophobic |
| MET 3 | NTc.Cm27 | TRP 94 | 23.50x50 | VdWContact |
| MET 3 | NTc.Cm27 | CYS 178 | 45.50x50 | Hydrophobic |
| MET 3 | NTc.Cm27 | CYS 178 | 45.50x50 | VdWContact |
| PHE 4 | NTc.Cm26 | MET 279 | 7.35x34 | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLN 280 | 7.36x35 | HBAcceptor |
| PHE 4 | NTc.Cm26 | GLN 280 | 7.36x35 | VdWContact |
| LYS 5 | NTc.Cm25 | TYR 89 | 2.63x63 | CationPi |
| LYS 5 | NTc.Cm25 | TYR 89 | 2.63x63 | Hydrophobic |
| LYS 5 | NTc.Cm25 | TYR 89 | 2.63x63 | VdWContact |
| LYS 5 | NTc.Cm25 | ALA 92 | 2.66x66 | HBDonor |
| LYS 5 | NTc.Cm25 | ALA 92 | 2.66x66 | VdWContact |
| LYS 5 | NTc.Cm25 | GLN 93 | 23.49x49 | VdWContact |
| ARG 6 | NTc.Cm24 | LYS 26 | 1.28x28 | VdWContact |
| ARG 6 | NTc.Cm24 | GLU 172 | - | Cationic |
| ARG 6 | NTc.Cm24 | GLU 172 | - | HBDonor |
| ARG 6 | NTc.Cm24 | GLU 172 | - | VdWContact |
| GLY 7 | NTc.Cm23 | LYS 22 | 1.24x24 | VdWContact |
| GLY 7 | NTc.Cm23 | ASP 276 | 7.32x31 | VdWContact |
| ARG 8 | NTc.Cm22 | LYS 22 | 1.24x24 | HBAcceptor |
| ARG 8 | NTc.Cm22 | LYS 22 | 1.24x24 | VdWContact |
| ARG 8 | NTc.Cm22 | GLN 261 | 6.61x61 | HBDonor |
| ARG 8 | NTc.Cm22 | GLN 261 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm22 | LEU 266 | - | HBDonor |
| ARG 8 | NTc.Cm22 | LEU 266 | - | VdWContact |
| ARG 8 | NTc.Cm22 | SER 271 | 7.27x26 | HBDonor |
| ARG 8 | NTc.Cm22 | SER 271 | 7.27x26 | VdWContact |
| ARG 8 | NTc.Cm22 | SER 272 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 276 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm22 | ASP 276 | 7.32x31 | VdWContact |
| LEU 10 | NTc.Cm20 | PRO 19 | - | Hydrophobic |
| LEU 10 | NTc.Cm20 | CYS 20 | - | HBAcceptor |
| LEU 10 | NTc.Cm20 | CYS 20 | - | VdWContact |
| LEU 10 | NTc.Cm20 | LYS 22 | 1.24x24 | Hydrophobic |
| ILE 12 | NTc.Cm18 | CYS 20 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | ASN 267 | - | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 269 | 7.25x24 | Hydrophobic |
| VAL 16 | NTc.Cm14 | SER 17 | - | VdWContact |
| PRO 32 | CX.5 | HIS 181 | - | HBAcceptor |
| PRO 32 | CX.5 | HIS 181 | - | VdWContact |
| PRO 32 | CX.5 | TYR 184 | - | Hydrophobic |
| PRO 32 | CX.5 | TYR 184 | - | VdWContact |
| SER 33 | cxb1.1 | TYR 187 | 5.31x32 | HBAcceptor |
| SER 33 | cxb1.1 | TYR 187 | 5.31x32 | VdWContact |
| ASN 34 | cxb1.2 | SER 180 | 45.52x52 | HBDonor |
| ASN 34 | cxb1.2 | SER 180 | 45.52x52 | VdWContact |
| ASN 34 | cxb1.2 | PHE 182 | - | VdWContact |
| ASN 34 | cxb1.2 | TYR 187 | 5.31x32 | VdWContact |
| ASP 37 | cxb1.7 | TYR 187 | 5.31x32 | Hydrophobic |
| ASP 37 | cxb1.7 | TYR 187 | 5.31x32 | VdWContact |
| ASP 37 | cxb1.7 | GLN 188 | 5.32x33 | VdWContact |
| ILE 42 | cxb1.15 | PRO 19 | - | Hydrophobic |
| GLN 51 | b1b2.4 | GLU 18 | - | VdWContact |
| GLN 51 | b1b2.4 | PRO 19 | - | Hydrophobic |
| GLN 51 | b1b2.4 | GLN 21 | - | HBAcceptor |
| GLN 51 | b1b2.4 | GLN 21 | - | VdWContact |
| ARG 52 | b1b2.6 | SER 17 | - | VdWContact |
| ARG 52 | b1b2.6 | GLU 18 | - | Cationic |
| ARG 52 | b1b2.6 | GLU 18 | - | HBDonor |
| ARG 52 | b1b2.6 | GLU 18 | - | VdWContact |
| CYS 53 | b1b2.7 | SER 17 | - | HBDonor |
| CYS 53 | b1b2.7 | SER 17 | - | VdWContact |
