Predicted complex interactions
CXCL13_HUMAN + CCR5
SUMMARY
- Chemokine
- CXCL13_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 88
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm32 | THR 105 | 3.29x29 | Hydrophobic |
| VAL 1 | NTc.Cm32 | THR 105 | 3.29x29 | VdWContact |
| VAL 1 | NTc.Cm32 | TYR 108 | 3.32x32 | Hydrophobic |
| VAL 1 | NTc.Cm32 | TYR 108 | 3.32x32 | VdWContact |
| VAL 1 | NTc.Cm32 | PHE 109 | 3.33x33 | Hydrophobic |
| VAL 1 | NTc.Cm32 | PHE 109 | 3.33x33 | VdWContact |
| VAL 1 | NTc.Cm32 | GLU 283 | 7.39x38 | Cationic |
| VAL 1 | NTc.Cm32 | GLU 283 | 7.39x38 | HBDonor |
| VAL 1 | NTc.Cm32 | GLU 283 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 37 | 1.39x39 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 37 | 1.39x39 | VdWContact |
| LEU 2 | NTc.Cm31 | TRP 86 | 2.60x60 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TRP 86 | 2.60x60 | VdWContact |
| LEU 2 | NTc.Cm31 | GLU 283 | 7.39x38 | Hydrophobic |
| LEU 2 | NTc.Cm31 | GLU 283 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm31 | MET 287 | 7.43x42 | Hydrophobic |
| LEU 2 | NTc.Cm31 | MET 287 | 7.43x42 | VdWContact |
| GLU 3 | NTc.Cm30 | ASN 258 | 6.58x58 | HBAcceptor |
| GLU 3 | NTc.Cm30 | ASN 258 | 6.58x58 | VdWContact |
| GLU 3 | NTc.Cm30 | MET 279 | 7.35x34 | Hydrophobic |
| GLU 3 | NTc.Cm30 | MET 279 | 7.35x34 | VdWContact |
| GLU 3 | NTc.Cm30 | GLU 283 | 7.39x38 | HBDonor |
| GLU 3 | NTc.Cm30 | GLU 283 | 7.39x38 | VdWContact |
| VAL 4 | NTc.Cm29 | ALA 29 | 1.31x31 | Hydrophobic |
| VAL 4 | NTc.Cm29 | LEU 33 | 1.35x35 | Hydrophobic |
| VAL 4 | NTc.Cm29 | GLN 280 | 7.36x35 | Hydrophobic |
| VAL 4 | NTc.Cm29 | GLN 280 | 7.36x35 | VdWContact |
| TYR 5 | NTc.Cm28 | TRP 86 | 2.60x60 | HBDonor |
| TYR 5 | NTc.Cm28 | TRP 86 | 2.60x60 | Hydrophobic |
| TYR 5 | NTc.Cm28 | TRP 86 | 2.60x60 | VdWContact |
| TYR 5 | NTc.Cm28 | TYR 89 | 2.63x63 | Hydrophobic |
| TYR 5 | NTc.Cm28 | TYR 89 | 2.63x63 | PiStacking |
| TYR 5 | NTc.Cm28 | TYR 89 | 2.63x63 | VdWContact |
| TYR 5 | NTc.Cm28 | ALA 90 | 2.64x64 | Hydrophobic |
| TYR 5 | NTc.Cm28 | ALA 90 | 2.64x64 | VdWContact |
| TYR 6 | NTc.Cm27 | SER 180 | 45.52x52 | HBAcceptor |
| TYR 6 | NTc.Cm27 | SER 180 | 45.52x52 | VdWContact |
| THR 7 | NTc.Cm26 | LYS 22 | 1.24x24 | VdWContact |
| THR 7 | NTc.Cm26 | VAL 25 | 1.27x27 | Hydrophobic |
| THR 7 | NTc.Cm26 | ASP 276 | 7.32x31 | Hydrophobic |
| THR 7 | NTc.Cm26 | ASP 276 | 7.32x31 | VdWContact |
| LEU 9 | NTc.Cm24 | GLU 172 | - | VdWContact |
| LEU 9 | NTc.Cm24 | SER 179 | 45.51x51 | VdWContact |
| ARG 10 | NTc.Cm23 | LYS 22 | 1.24x24 | Hydrophobic |
| ARG 10 | NTc.Cm23 | LYS 22 | 1.24x24 | VdWContact |
| ARG 10 | NTc.Cm23 | ASN 258 | 6.58x58 | VdWContact |
| ARG 10 | NTc.Cm23 | SER 272 | 7.28x27 | HBDonor |
| ARG 10 | NTc.Cm23 | SER 272 | 7.28x27 | VdWContact |
| ARG 10 | NTc.Cm23 | ASP 276 | 7.32x31 | Cationic |
| ARG 10 | NTc.Cm23 | ASP 276 | 7.32x31 | VdWContact |
| ARG 12 | NTc.Cm21 | PRO 19 | - | Hydrophobic |
| ARG 12 | NTc.Cm21 | PRO 19 | - | VdWContact |
| ARG 12 | NTc.Cm21 | CYS 20 | - | HBAcceptor |
| ARG 12 | NTc.Cm21 | CYS 20 | - | VdWContact |
| VAL 14 | NTc.Cm19 | CYS 20 | - | Hydrophobic |
| VAL 14 | NTc.Cm19 | ASN 267 | - | VdWContact |
| VAL 14 | NTc.Cm19 | ASN 268 | 7.24x23 | VdWContact |
| VAL 14 | NTc.Cm19 | CYS 269 | 7.25x24 | Hydrophobic |
| GLN 15 | NTc.Cm18 | THR 16 | - | VdWContact |
| VAL 19 | NTc.Cm14 | ILE 12 | - | Hydrophobic |
| VAL 19 | NTc.Cm14 | ILE 12 | - | VdWContact |
| VAL 19 | NTc.Cm14 | TYR 14 | - | Hydrophobic |
| ILE 21 | NTc.Cm12 | TYR 14 | - | Hydrophobic |
| ARG 34 | CX.4 | TYR 184 | - | CationPi |
| ARG 34 | CX.4 | TYR 184 | - | VdWContact |
| ASN 36 | cxb1.1 | SER 179 | 45.51x51 | HBDonor |
| ASN 36 | cxb1.1 | SER 179 | 45.51x51 | VdWContact |
| ASN 36 | cxb1.1 | SER 180 | 45.52x52 | VdWContact |
| ASN 36 | cxb1.1 | HIS 181 | - | HBDonor |
| ASN 36 | cxb1.1 | HIS 181 | - | VdWContact |
| ASN 36 | cxb1.1 | TYR 187 | 5.31x32 | HBAcceptor |
| ASN 36 | cxb1.1 | TYR 187 | 5.31x32 | VdWContact |
| PRO 39 | cxb1.6 | TYR 184 | - | VdWContact |
| PRO 39 | cxb1.6 | TYR 187 | 5.31x32 | Hydrophobic |
| PRO 39 | cxb1.6 | TYR 187 | 5.31x32 | VdWContact |
| ILE 44 | cxb1.14 | PRO 19 | - | Hydrophobic |
| LYS 47 | B1.1 | TYR 14 | - | CationPi |
| LYS 47 | B1.1 | TYR 14 | - | VdWContact |
| ILE 52 | B1.6 | GLU 18 | - | Hydrophobic |
| ILE 52 | B1.6 | GLU 18 | - | VdWContact |
| ILE 52 | B1.6 | PRO 19 | - | Hydrophobic |
| ILE 52 | B1.6 | PRO 19 | - | VdWContact |
| VAL 53 | B1.7 | TYR 14 | - | Hydrophobic |
| VAL 53 | B1.7 | TYR 14 | - | VdWContact |
| VAL 53 | B1.7 | SER 17 | - | VdWContact |
| CYS 54 | b1b2.4 | SER 17 | - | HBDonor |
| CYS 54 | b1b2.4 | SER 17 | - | VdWContact |
| CYS 54 | b1b2.4 | PRO 19 | - | VdWContact |
