Predicted complex interactions
CXCL14_HUMAN + CCR5
SUMMARY
- Chemokine
- CXCL14_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 108
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm36 | LYS 191 | 5.35x36 | VdWContact |
| SER 1 | NTc.Cm36 | ASN 258 | 6.58x58 | VdWContact |
| SER 1 | NTc.Cm36 | THR 259 | 6.59x59 | VdWContact |
| SER 1 | NTc.Cm36 | GLN 261 | 6.61x61 | HBDonor |
| SER 1 | NTc.Cm36 | GLN 261 | 6.61x61 | VdWContact |
| LYS 2 | NTc.Cm35 | TYR 187 | 5.31x32 | VdWContact |
| LYS 2 | NTc.Cm35 | LYS 191 | 5.35x36 | HBAcceptor |
| LYS 2 | NTc.Cm35 | LYS 191 | 5.35x36 | Hydrophobic |
| LYS 2 | NTc.Cm35 | LYS 191 | 5.35x36 | VdWContact |
| LYS 2 | NTc.Cm35 | ASN 258 | 6.58x58 | HBDonor |
| LYS 2 | NTc.Cm35 | ASN 258 | 6.58x58 | VdWContact |
| CYS 3 | NTc.Cm34 | TYR 187 | 5.31x32 | Hydrophobic |
| CYS 3 | NTc.Cm34 | TYR 187 | 5.31x32 | VdWContact |
| CYS 3 | NTc.Cm34 | GLN 188 | 5.32x33 | VdWContact |
| LYS 4 | NTc.Cm33 | GLU 262 | 6.62x62 | Cationic |
| LYS 4 | NTc.Cm33 | GLU 262 | 6.62x62 | HBDonor |
| LYS 4 | NTc.Cm33 | GLU 262 | 6.62x62 | Hydrophobic |
| LYS 4 | NTc.Cm33 | GLU 262 | 6.62x62 | VdWContact |
| SER 6 | NTc.Cm31 | ASN 267 | - | VdWContact |
| SER 6 | NTc.Cm31 | ASN 268 | 7.24x23 | VdWContact |
| SER 6 | NTc.Cm31 | CYS 269 | 7.25x24 | VdWContact |
| ARG 7 | NTc.Cm30 | GLU 262 | 6.62x62 | Cationic |
| ARG 7 | NTc.Cm30 | ASN 267 | - | HBDonor |
| ARG 7 | NTc.Cm30 | ASN 267 | - | VdWContact |
| LYS 8 | NTc.Cm29 | TYR 15 | - | Hydrophobic |
| LYS 8 | NTc.Cm29 | TYR 15 | - | VdWContact |
| LYS 8 | NTc.Cm29 | SER 17 | - | HBAcceptor |
| LYS 8 | NTc.Cm29 | SER 17 | - | VdWContact |
| GLY 9 | NTc.Cm28 | TYR 14 | - | VdWContact |
| GLY 9 | NTc.Cm28 | TYR 15 | - | VdWContact |
| GLY 9 | NTc.Cm28 | THR 16 | - | VdWContact |
| GLY 9 | NTc.Cm28 | SER 17 | - | VdWContact |
| PRO 10 | NTc.Cm27 | THR 16 | - | VdWContact |
| PRO 10 | NTc.Cm27 | SER 17 | - | VdWContact |
| PRO 10 | NTc.Cm27 | GLU 18 | - | VdWContact |
| PRO 10 | NTc.Cm27 | PRO 19 | - | VdWContact |
| LYS 11 | NTc.Cm26 | ASP 11 | - | Cationic |
| LYS 11 | NTc.Cm26 | ASP 11 | - | HBDonor |
| LYS 11 | NTc.Cm26 | ASP 11 | - | VdWContact |
| LYS 11 | NTc.Cm26 | THR 16 | - | Hydrophobic |
| LYS 11 | NTc.Cm26 | THR 16 | - | VdWContact |
| ILE 12 | NTc.Cm25 | TYR 14 | - | Hydrophobic |
| ILE 12 | NTc.Cm25 | TYR 14 | - | VdWContact |
| TYR 14 | NTc.Cm23 | TYR 10 | - | Hydrophobic |
| TYR 14 | NTc.Cm23 | ILE 12 | - | Hydrophobic |
| TYR 14 | NTc.Cm23 | ILE 12 | - | VdWContact |
| MET 22 | NTc.Cm15 | TYR 184 | - | VdWContact |
| LYS 23 | NTc.Cm14 | TYR 184 | - | Hydrophobic |
| LYS 23 | NTc.Cm14 | TYR 184 | - | VdWContact |
| PRO 24 | NTc.Cm13 | TYR 184 | - | Hydrophobic |
| PRO 24 | NTc.Cm13 | TYR 184 | - | VdWContact |
| PRO 24 | NTc.Cm13 | TYR 187 | 5.31x32 | Hydrophobic |
| PRO 24 | NTc.Cm13 | TYR 187 | 5.31x32 | VdWContact |
| LYS 25 | NTc.Cm12 | TYR 187 | 5.31x32 | Hydrophobic |
| TYR 26 | NTc.Cm11 | TYR 187 | 5.31x32 | Hydrophobic |
| TYR 26 | NTc.Cm11 | TYR 187 | 5.31x32 | VdWContact |
| PRO 27 | NTc.Cm10 | HIS 181 | - | Hydrophobic |
| PRO 27 | NTc.Cm10 | HIS 181 | - | VdWContact |
| PRO 27 | NTc.Cm10 | PHE 182 | - | VdWContact |
| PRO 27 | NTc.Cm10 | PRO 183 | - | VdWContact |
| PRO 27 | NTc.Cm10 | TYR 187 | 5.31x32 | VdWContact |
| HIS 28 | NTc.Cm9 | SER 180 | 45.52x52 | VdWContact |
| HIS 28 | NTc.Cm9 | PHE 182 | - | Hydrophobic |
| HIS 28 | NTc.Cm9 | PHE 182 | - | VdWContact |
| HIS 28 | NTc.Cm9 | TYR 187 | 5.31x32 | Hydrophobic |
| HIS 28 | NTc.Cm9 | TYR 187 | 5.31x32 | VdWContact |
| HIS 28 | NTc.Cm9 | LYS 191 | 5.35x36 | Hydrophobic |
| HIS 28 | NTc.Cm9 | LYS 191 | 5.35x36 | VdWContact |
| CYS 29 | NTc.Cm8 | TYR 184 | - | VdWContact |
| CYS 29 | NTc.Cm8 | TYR 187 | 5.31x32 | Hydrophobic |
| CYS 29 | NTc.Cm8 | TYR 187 | 5.31x32 | VdWContact |
| CYS 29 | NTc.Cm8 | GLN 188 | 5.32x33 | VdWContact |
| GLU 30 | NTc.Cm7 | GLN 188 | 5.32x33 | HBAcceptor |
| GLU 30 | NTc.Cm7 | GLN 188 | 5.32x33 | VdWContact |
| GLU 30 | NTc.Cm7 | PHE 189 | 5.33x34 | HBAcceptor |
| GLU 30 | NTc.Cm7 | PHE 189 | 5.33x34 | VdWContact |
| LYS 32 | NTc.Cm5 | TYR 184 | - | Hydrophobic |
| LYS 32 | NTc.Cm5 | TYR 184 | - | VdWContact |
| MET 33 | NTc.Cm4 | TYR 184 | - | HBAcceptor |
| MET 33 | NTc.Cm4 | TYR 184 | - | HBDonor |
| MET 33 | NTc.Cm4 | TYR 184 | - | VdWContact |
| ILE 36 | NTc.Cm1 | TYR 14 | - | Hydrophobic |
| ILE 36 | NTc.Cm1 | TYR 14 | - | VdWContact |
| ARG 43 | cxb1.6 | GLU 18 | - | Cationic |
| ARG 43 | cxb1.6 | GLU 18 | - | HBDonor |
| ARG 43 | cxb1.6 | GLU 18 | - | VdWContact |
| TYR 44 | cxb1.8 | GLU 18 | - | Hydrophobic |
| TYR 44 | cxb1.8 | GLU 18 | - | VdWContact |
| GLN 47 | cxb1.14 | PRO 19 | - | Hydrophobic |
| GLN 47 | cxb1.14 | PRO 19 | - | VdWContact |
| GLN 47 | cxb1.14 | GLN 21 | - | HBAcceptor |
| GLN 47 | cxb1.14 | GLN 21 | - | VdWContact |
| HIS 49 | cxb1.16 | PRO 19 | - | Hydrophobic |
| HIS 49 | cxb1.16 | PRO 19 | - | VdWContact |
| LEU 51 | B1.2 | TYR 14 | - | Hydrophobic |
| LEU 51 | B1.2 | TYR 14 | - | VdWContact |
| SER 57 | b1b2.4 | ASN 13 | - | VdWContact |
| SER 57 | b1b2.4 | TYR 14 | - | VdWContact |
| ARG 60 | b1b2.8 | ILE 12 | - | Hydrophobic |
| PHE 61 | b1b2.9 | ILE 12 | - | Hydrophobic |
| PHE 61 | b1b2.9 | ILE 12 | - | VdWContact |
| PHE 61 | b1b2.9 | TYR 14 | - | Hydrophobic |
| PHE 61 | b1b2.9 | TYR 14 | - | VdWContact |
| TRP 64 | b1b2.13 | TYR 10 | - | Hydrophobic |
| TRP 64 | b1b2.13 | TYR 10 | - | PiStacking |
| TRP 64 | b1b2.13 | TYR 10 | - | VdWContact |
| TRP 68 | B2.1 | SER 7 | - | HBDonor |
| TRP 68 | B2.1 | SER 7 | - | VdWContact |
