Predicted complex interactions
CXCL16_HUMAN + CCR5
SUMMARY
- Chemokine
- CXCL16_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 64
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASN 1 | NTc.Cm56 | TYR 37 | 1.39x39 | VdWContact |
| ASN 1 | NTc.Cm56 | TRP 86 | 2.60x60 | Hydrophobic |
| ASN 1 | NTc.Cm56 | TRP 86 | 2.60x60 | VdWContact |
| ASN 1 | NTc.Cm56 | TYR 108 | 3.32x32 | Hydrophobic |
| ASN 1 | NTc.Cm56 | GLU 283 | 7.39x38 | HBDonor |
| ASN 1 | NTc.Cm56 | GLU 283 | 7.39x38 | VdWContact |
| ASN 1 | NTc.Cm56 | MET 287 | 7.43x42 | Hydrophobic |
| GLU 2 | NTc.Cm55 | MET 279 | 7.35x34 | Hydrophobic |
| GLU 2 | NTc.Cm55 | GLU 283 | 7.39x38 | HBDonor |
| GLU 2 | NTc.Cm55 | GLU 283 | 7.39x38 | VdWContact |
| GLY 3 | NTc.Cm54 | GLN 280 | 7.36x35 | HBAcceptor |
| GLY 3 | NTc.Cm54 | GLN 280 | 7.36x35 | VdWContact |
| GLY 3 | NTc.Cm54 | GLU 283 | 7.39x38 | HBDonor |
| GLY 3 | NTc.Cm54 | GLU 283 | 7.39x38 | VdWContact |
| VAL 5 | NTc.Cm52 | TYR 89 | 2.63x63 | Hydrophobic |
| VAL 5 | NTc.Cm52 | CYS 178 | 45.50x50 | VdWContact |
| THR 6 | NTc.Cm51 | VAL 25 | 1.27x27 | Hydrophobic |
| THR 6 | NTc.Cm51 | ASP 276 | 7.32x31 | Hydrophobic |
| THR 6 | NTc.Cm51 | ASP 276 | 7.32x31 | VdWContact |
| THR 6 | NTc.Cm51 | GLN 280 | 7.36x35 | Hydrophobic |
| THR 6 | NTc.Cm51 | GLN 280 | 7.36x35 | VdWContact |
| GLY 7 | NTc.Cm50 | LYS 26 | 1.28x28 | HBAcceptor |
| GLY 7 | NTc.Cm50 | LYS 26 | 1.28x28 | VdWContact |
| SER 8 | NTc.Cm49 | LYS 26 | 1.28x28 | VdWContact |
| CYS 9 | NTc.Cm48 | GLU 172 | - | HBDonor |
| CYS 9 | NTc.Cm48 | GLU 172 | - | VdWContact |
| TYR 10 | NTc.Cm47 | SER 180 | 45.52x52 | VdWContact |
| TYR 10 | NTc.Cm47 | HIS 181 | - | HBAcceptor |
| TYR 10 | NTc.Cm47 | HIS 181 | - | Hydrophobic |
| TYR 10 | NTc.Cm47 | HIS 181 | - | VdWContact |
| TYR 10 | NTc.Cm47 | TYR 187 | 5.31x32 | Hydrophobic |
| ARG 14 | NTc.Cm43 | GLY 173 | - | HBDonor |
| ARG 14 | NTc.Cm43 | GLY 173 | - | VdWContact |
| ARG 34 | NTc.Cm23 | GLU 262 | 6.62x62 | Cationic |
| ARG 34 | NTc.Cm23 | GLU 262 | 6.62x62 | HBDonor |
| ARG 34 | NTc.Cm23 | GLU 262 | 6.62x62 | VdWContact |
| TYR 36 | NTc.Cm21 | PRO 19 | - | Hydrophobic |
| TYR 36 | NTc.Cm21 | PRO 19 | - | VdWContact |
| TYR 36 | NTc.Cm21 | CYS 20 | - | HBAcceptor |
| TYR 36 | NTc.Cm21 | CYS 20 | - | VdWContact |
| HIS 37 | NTc.Cm20 | CYS 20 | - | Hydrophobic |
| HIS 37 | NTc.Cm20 | CYS 20 | - | VdWContact |
| HIS 37 | NTc.Cm20 | LYS 22 | 1.24x24 | VdWContact |
| ARG 38 | NTc.Cm19 | PRO 19 | - | Hydrophobic |
| ARG 38 | NTc.Cm19 | PRO 19 | - | VdWContact |
| ARG 38 | NTc.Cm19 | GLN 21 | - | Hydrophobic |
| LEU 40 | NTc.Cm17 | ILE 23 | 1.25x25 | Hydrophobic |
| LEU 40 | NTc.Cm17 | HIS 175 | - | Hydrophobic |
| TYR 41 | NTc.Cm16 | GLY 173 | - | VdWContact |
| TYR 41 | NTc.Cm16 | LEU 174 | - | Hydrophobic |
| TYR 41 | NTc.Cm16 | LEU 174 | - | VdWContact |
| TYR 41 | NTc.Cm16 | HIS 175 | - | Hydrophobic |
| TYR 41 | NTc.Cm16 | HIS 175 | - | VdWContact |
| TYR 42 | NTc.Cm15 | GLU 172 | - | Hydrophobic |
| TYR 42 | NTc.Cm15 | GLU 172 | - | VdWContact |
| SER 49 | NTc.Cm8 | TYR 184 | - | VdWContact |
| SER 49 | NTc.Cm8 | TYR 187 | 5.31x32 | VdWContact |
| TRP 50 | NTc.Cm7 | TYR 184 | - | Hydrophobic |
| TRP 50 | NTc.Cm7 | TYR 184 | - | PiStacking |
| TRP 50 | NTc.Cm7 | TYR 184 | - | VdWContact |
| MET 65 | cxb1.8 | PRO 19 | - | Hydrophobic |
| MET 65 | cxb1.8 | PRO 19 | - | VdWContact |
| LEU 70 | cxb1.16 | TYR 14 | - | VdWContact |
| LYS 71 | B1.1 | TYR 14 | - | Hydrophobic |
