Predicted complex interactions
CXCL4_HUMAN + CCR5
SUMMARY
- Chemokine
- CXCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 63
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLU 4 | NTc.Cm37 | ASN 24 | 1.26x26 | HBAcceptor |
| GLU 4 | NTc.Cm37 | ASN 24 | 1.26x26 | VdWContact |
| GLU 4 | NTc.Cm37 | LYS 26 | 1.28x28 | Hydrophobic |
| ASP 5 | NTc.Cm36 | GLU 172 | - | Hydrophobic |
| ASP 5 | NTc.Cm36 | GLU 172 | - | VdWContact |
| LEU 8 | NTc.Cm33 | LYS 22 | 1.24x24 | Hydrophobic |
| LEU 8 | NTc.Cm33 | ILE 23 | 1.25x25 | VdWContact |
| LEU 8 | NTc.Cm33 | VAL 25 | 1.27x27 | Hydrophobic |
| LEU 8 | NTc.Cm33 | ASP 276 | 7.32x31 | Hydrophobic |
| GLN 9 | NTc.Cm32 | LYS 22 | 1.24x24 | VdWContact |
| GLN 9 | NTc.Cm32 | ASN 258 | 6.58x58 | VdWContact |
| GLN 9 | NTc.Cm32 | GLN 261 | 6.61x61 | HBAcceptor |
| GLN 9 | NTc.Cm32 | GLN 261 | 6.61x61 | VdWContact |
| GLN 9 | NTc.Cm32 | SER 272 | 7.28x27 | HBAcceptor |
| GLN 9 | NTc.Cm32 | SER 272 | 7.28x27 | HBDonor |
| GLN 9 | NTc.Cm32 | SER 272 | 7.28x27 | VdWContact |
| GLN 9 | NTc.Cm32 | LEU 275 | 7.31x30 | VdWContact |
| GLN 9 | NTc.Cm32 | ASP 276 | 7.32x31 | HBDonor |
| GLN 9 | NTc.Cm32 | ASP 276 | 7.32x31 | VdWContact |
| CYS 10 | NTc.Cm31 | LYS 22 | 1.24x24 | VdWContact |
| LEU 11 | NTc.Cm30 | PRO 19 | - | Hydrophobic |
| LEU 11 | NTc.Cm30 | CYS 20 | - | HBAcceptor |
| LEU 11 | NTc.Cm30 | CYS 20 | - | VdWContact |
| LEU 11 | NTc.Cm30 | LYS 22 | 1.24x24 | Hydrophobic |
| VAL 13 | NTc.Cm28 | CYS 20 | - | VdWContact |
| VAL 13 | NTc.Cm28 | ASN 267 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | ASN 267 | - | VdWContact |
| LYS 14 | NTc.Cm27 | THR 16 | - | VdWContact |
| LYS 14 | NTc.Cm27 | ASN 267 | - | VdWContact |
| THR 16 | NTc.Cm25 | TYR 14 | - | Hydrophobic |
| GLN 18 | NTc.Cm23 | ILE 12 | - | VdWContact |
| VAL 19 | NTc.Cm22 | TYR 14 | - | Hydrophobic |
| VAL 19 | NTc.Cm22 | TYR 14 | - | VdWContact |
| ARG 20 | NTc.Cm21 | ILE 9 | - | VdWContact |
| HIS 23 | NTc.Cm18 | ILE 9 | - | Hydrophobic |
| HIS 23 | NTc.Cm18 | ILE 9 | - | VdWContact |
| HIS 23 | NTc.Cm18 | TYR 10 | - | Hydrophobic |
| HIS 23 | NTc.Cm18 | TYR 10 | - | PiStacking |
| PRO 34 | NTc.Cm7 | SER 179 | 45.51x51 | VdWContact |
| PRO 34 | NTc.Cm7 | SER 180 | 45.52x52 | VdWContact |
| PRO 34 | NTc.Cm7 | HIS 181 | - | Hydrophobic |
| PRO 34 | NTc.Cm7 | HIS 181 | - | VdWContact |
| PRO 34 | NTc.Cm7 | TYR 187 | 5.31x32 | HBAcceptor |
| PRO 34 | NTc.Cm7 | TYR 187 | 5.31x32 | VdWContact |
| PRO 37 | NTc.Cm4 | TYR 187 | 5.31x32 | Hydrophobic |
| PRO 37 | NTc.Cm4 | TYR 187 | 5.31x32 | VdWContact |
| ILE 42 | CX.4 | PRO 19 | - | Hydrophobic |
| LEU 45 | cxb1.2 | TYR 14 | - | Hydrophobic |
| ARG 49 | cxb1.10 | TYR 15 | - | CationPi |
| ARG 49 | cxb1.10 | TYR 15 | - | HBDonor |
| ARG 49 | cxb1.10 | TYR 15 | - | VdWContact |
| ARG 49 | cxb1.10 | GLU 18 | - | Cationic |
| ARG 49 | cxb1.10 | GLU 18 | - | VdWContact |
| LYS 50 | cxb1.11 | PRO 19 | - | Hydrophobic |
| LYS 50 | cxb1.11 | PRO 19 | - | VdWContact |
| ILE 51 | cxb1.14 | TYR 14 | - | Hydrophobic |
| ILE 51 | cxb1.14 | TYR 14 | - | VdWContact |
| ILE 51 | cxb1.14 | SER 17 | - | VdWContact |
| ILE 51 | cxb1.14 | PRO 19 | - | VdWContact |
| CYS 52 | cxb1.15 | SER 17 | - | HBDonor |
| CYS 52 | cxb1.15 | SER 17 | - | VdWContact |
| CYS 52 | cxb1.15 | PRO 19 | - | VdWContact |
| GLN 56 | B1.3 | TYR 184 | - | VdWContact |
