Predicted complex interactions
CXCL5_HUMAN + CCR5
SUMMARY
- Chemokine
- CXCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 93
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm48 | THR 105 | 3.29x29 | VdWContact |
| ALA 1 | NTc.Cm48 | PHE 109 | 3.33x33 | VdWContact |
| ALA 1 | NTc.Cm48 | THR 167 | 4.64x65 | VdWContact |
| GLY 2 | NTc.Cm47 | TRP 86 | 2.60x60 | VdWContact |
| PRO 3 | NTc.Cm46 | TRP 86 | 2.60x60 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TRP 86 | 2.60x60 | VdWContact |
| PRO 3 | NTc.Cm46 | TYR 108 | 3.32x32 | Hydrophobic |
| PRO 3 | NTc.Cm46 | GLU 283 | 7.39x38 | Hydrophobic |
| PRO 3 | NTc.Cm46 | GLU 283 | 7.39x38 | VdWContact |
| PRO 3 | NTc.Cm46 | MET 287 | 7.43x42 | Hydrophobic |
| PRO 3 | NTc.Cm46 | MET 287 | 7.43x42 | VdWContact |
| ALA 4 | NTc.Cm45 | MET 279 | 7.35x34 | Hydrophobic |
| ALA 4 | NTc.Cm45 | GLU 283 | 7.39x38 | HBDonor |
| ALA 4 | NTc.Cm45 | GLU 283 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm44 | LEU 33 | 1.35x35 | Hydrophobic |
| ALA 5 | NTc.Cm44 | GLN 280 | 7.36x35 | HBAcceptor |
| ALA 5 | NTc.Cm44 | GLN 280 | 7.36x35 | Hydrophobic |
| ALA 5 | NTc.Cm44 | GLN 280 | 7.36x35 | VdWContact |
| ALA 5 | NTc.Cm44 | GLU 283 | 7.39x38 | HBDonor |
| ALA 5 | NTc.Cm44 | GLU 283 | 7.39x38 | VdWContact |
| ALA 6 | NTc.Cm43 | TRP 86 | 2.60x60 | Hydrophobic |
| ALA 6 | NTc.Cm43 | TYR 89 | 2.63x63 | Hydrophobic |
| VAL 7 | NTc.Cm42 | TYR 89 | 2.63x63 | Hydrophobic |
| VAL 7 | NTc.Cm42 | TYR 89 | 2.63x63 | VdWContact |
| LEU 8 | NTc.Cm41 | ASP 276 | 7.32x31 | Hydrophobic |
| LEU 8 | NTc.Cm41 | MET 279 | 7.35x34 | Hydrophobic |
| LEU 8 | NTc.Cm41 | MET 279 | 7.35x34 | VdWContact |
| ARG 9 | NTc.Cm40 | LYS 26 | 1.28x28 | Hydrophobic |
| ARG 9 | NTc.Cm40 | LYS 26 | 1.28x28 | VdWContact |
| ARG 9 | NTc.Cm40 | ALA 90 | 2.64x64 | HBDonor |
| ARG 9 | NTc.Cm40 | ALA 90 | 2.64x64 | VdWContact |
| ARG 9 | NTc.Cm40 | ALA 91 | 2.65x65 | HBDonor |
| ARG 9 | NTc.Cm40 | ALA 91 | 2.65x65 | VdWContact |
| ARG 9 | NTc.Cm40 | ALA 92 | 2.66x66 | VdWContact |
| GLU 10 | NTc.Cm39 | GLU 172 | - | VdWContact |
| GLU 10 | NTc.Cm39 | THR 177 | - | HBAcceptor |
| GLU 10 | NTc.Cm39 | THR 177 | - | Hydrophobic |
| GLU 10 | NTc.Cm39 | THR 177 | - | VdWContact |
| LEU 11 | NTc.Cm38 | LYS 22 | 1.24x24 | Hydrophobic |
| LEU 11 | NTc.Cm38 | LYS 22 | 1.24x24 | VdWContact |
| LEU 11 | NTc.Cm38 | VAL 25 | 1.27x27 | Hydrophobic |
| LEU 11 | NTc.Cm38 | LYS 26 | 1.28x28 | Hydrophobic |
| LEU 11 | NTc.Cm38 | ASP 276 | 7.32x31 | Hydrophobic |
| LEU 11 | NTc.Cm38 | ASP 276 | 7.32x31 | VdWContact |
| ARG 12 | NTc.Cm37 | LYS 22 | 1.24x24 | HBAcceptor |
| ARG 12 | NTc.Cm37 | LYS 22 | 1.24x24 | VdWContact |
| ARG 12 | NTc.Cm37 | ASN 258 | 6.58x58 | HBDonor |
| ARG 12 | NTc.Cm37 | ASN 258 | 6.58x58 | VdWContact |
| ARG 12 | NTc.Cm37 | GLN 261 | 6.61x61 | HBDonor |
| ARG 12 | NTc.Cm37 | GLN 261 | 6.61x61 | VdWContact |
| ARG 12 | NTc.Cm37 | SER 272 | 7.28x27 | VdWContact |
| ARG 12 | NTc.Cm37 | LEU 275 | 7.31x30 | VdWContact |
| ARG 12 | NTc.Cm37 | ASP 276 | 7.32x31 | Cationic |
| ARG 12 | NTc.Cm37 | ASP 276 | 7.32x31 | HBDonor |
| ARG 12 | NTc.Cm37 | ASP 276 | 7.32x31 | VdWContact |
| VAL 14 | NTc.Cm35 | PRO 19 | - | Hydrophobic |
| VAL 14 | NTc.Cm35 | PRO 19 | - | VdWContact |
| VAL 14 | NTc.Cm35 | CYS 20 | - | HBAcceptor |
| VAL 14 | NTc.Cm35 | CYS 20 | - | VdWContact |
| LEU 16 | NTc.Cm33 | CYS 20 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | ASN 267 | - | VdWContact |
| LEU 16 | NTc.Cm33 | ASN 268 | 7.24x23 | VdWContact |
| LEU 16 | NTc.Cm33 | CYS 269 | 7.25x24 | Hydrophobic |
| GLN 17 | NTc.Cm32 | SER 17 | - | VdWContact |
| THR 19 | NTc.Cm30 | TYR 14 | - | Hydrophobic |
| THR 19 | NTc.Cm30 | THR 16 | - | VdWContact |
| THR 19 | NTc.Cm30 | SER 17 | - | HBAcceptor |
| THR 19 | NTc.Cm30 | SER 17 | - | HBDonor |
| THR 19 | NTc.Cm30 | SER 17 | - | VdWContact |
| GLY 21 | NTc.Cm28 | TYR 14 | - | VdWContact |
| ILE 35 | NTc.Cm14 | TYR 184 | - | Hydrophobic |
| ILE 35 | NTc.Cm14 | TYR 184 | - | VdWContact |
| GLY 36 | NTc.Cm13 | TYR 187 | 5.31x32 | VdWContact |
| PRO 37 | NTc.Cm12 | SER 179 | 45.51x51 | VdWContact |
| PRO 37 | NTc.Cm12 | SER 180 | 45.52x52 | VdWContact |
| PRO 37 | NTc.Cm12 | HIS 181 | - | Hydrophobic |
| PRO 37 | NTc.Cm12 | HIS 181 | - | VdWContact |
| PRO 37 | NTc.Cm12 | TYR 187 | 5.31x32 | HBAcceptor |
| PRO 37 | NTc.Cm12 | TYR 187 | 5.31x32 | VdWContact |
| SER 40 | NTc.Cm9 | TYR 184 | - | VdWContact |
| SER 40 | NTc.Cm9 | TYR 187 | 5.31x32 | VdWContact |
| LYS 41 | NTc.Cm8 | GLU 262 | 6.62x62 | Cationic |
| VAL 45 | NTc.Cm4 | PRO 19 | - | Hydrophobic |
| LYS 52 | cxb1.1 | GLU 18 | - | Cationic |
| LYS 52 | cxb1.1 | GLU 18 | - | HBDonor |
| LYS 52 | cxb1.1 | GLU 18 | - | VdWContact |
| GLU 53 | cxb1.2 | GLU 18 | - | VdWContact |
| GLU 53 | cxb1.2 | PRO 19 | - | Hydrophobic |
| GLU 53 | cxb1.2 | PRO 19 | - | VdWContact |
| ILE 54 | cxb1.5 | THR 16 | - | Hydrophobic |
| ILE 54 | cxb1.5 | THR 16 | - | VdWContact |
| CYS 55 | cxb1.6 | SER 17 | - | HBDonor |
| CYS 55 | cxb1.6 | SER 17 | - | VdWContact |
