Predicted complex interactions
CXCL6_HUMAN + CCR5
SUMMARY
- Chemokine
- CXCL6_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 82
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm48 | TYR 37 | 1.39x39 | HBDonor |
| GLY 1 | NTc.Cm48 | TYR 37 | 1.39x39 | VdWContact |
| GLY 1 | NTc.Cm48 | GLU 283 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm48 | GLU 283 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm48 | GLU 283 | 7.39x38 | VdWContact |
| GLY 1 | NTc.Cm48 | MET 287 | 7.43x42 | VdWContact |
| PRO 2 | NTc.Cm47 | TRP 86 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm47 | TRP 86 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm47 | TYR 108 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm47 | TYR 108 | 3.32x32 | VdWContact |
| VAL 3 | NTc.Cm46 | PHE 109 | 3.33x33 | Hydrophobic |
| VAL 3 | NTc.Cm46 | TYR 251 | 6.51x51 | Hydrophobic |
| VAL 3 | NTc.Cm46 | LEU 255 | 6.55x55 | Hydrophobic |
| VAL 3 | NTc.Cm46 | GLU 283 | 7.39x38 | HBDonor |
| VAL 3 | NTc.Cm46 | GLU 283 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm45 | GLN 280 | 7.36x35 | VdWContact |
| SER 4 | NTc.Cm45 | GLU 283 | 7.39x38 | HBDonor |
| SER 4 | NTc.Cm45 | GLU 283 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm44 | TYR 89 | 2.63x63 | HBAcceptor |
| ALA 5 | NTc.Cm44 | TYR 89 | 2.63x63 | Hydrophobic |
| ALA 5 | NTc.Cm44 | TYR 89 | 2.63x63 | VdWContact |
| VAL 6 | NTc.Cm43 | CYS 178 | 45.50x50 | VdWContact |
| VAL 6 | NTc.Cm43 | SER 179 | 45.51x51 | VdWContact |
| LEU 7 | NTc.Cm42 | ASN 258 | 6.58x58 | VdWContact |
| LEU 7 | NTc.Cm42 | MET 279 | 7.35x34 | Hydrophobic |
| LEU 7 | NTc.Cm42 | MET 279 | 7.35x34 | VdWContact |
| THR 8 | NTc.Cm41 | LYS 26 | 1.28x28 | VdWContact |
| THR 8 | NTc.Cm41 | ALA 29 | 1.31x31 | Hydrophobic |
| THR 8 | NTc.Cm41 | GLN 280 | 7.36x35 | VdWContact |
| GLU 9 | NTc.Cm40 | THR 177 | - | HBAcceptor |
| GLU 9 | NTc.Cm40 | THR 177 | - | Hydrophobic |
| GLU 9 | NTc.Cm40 | THR 177 | - | VdWContact |
| GLU 9 | NTc.Cm40 | SER 179 | 45.51x51 | HBAcceptor |
| GLU 9 | NTc.Cm40 | SER 179 | 45.51x51 | VdWContact |
| LEU 10 | NTc.Cm39 | LYS 22 | 1.24x24 | Hydrophobic |
| LEU 10 | NTc.Cm39 | LYS 22 | 1.24x24 | VdWContact |
| ARG 11 | NTc.Cm38 | LYS 22 | 1.24x24 | HBAcceptor |
| ARG 11 | NTc.Cm38 | LYS 22 | 1.24x24 | VdWContact |
| ARG 11 | NTc.Cm38 | ASN 258 | 6.58x58 | HBDonor |
| ARG 11 | NTc.Cm38 | ASN 258 | 6.58x58 | VdWContact |
| ARG 11 | NTc.Cm38 | GLN 261 | 6.61x61 | VdWContact |
| ARG 11 | NTc.Cm38 | LEU 266 | - | HBDonor |
| ARG 11 | NTc.Cm38 | LEU 266 | - | VdWContact |
| ARG 11 | NTc.Cm38 | SER 272 | 7.28x27 | VdWContact |
| ARG 11 | NTc.Cm38 | LEU 275 | 7.31x30 | VdWContact |
| ARG 11 | NTc.Cm38 | ASP 276 | 7.32x31 | Cationic |
| THR 13 | NTc.Cm36 | PRO 19 | - | VdWContact |
| THR 13 | NTc.Cm36 | CYS 20 | - | HBAcceptor |
| THR 13 | NTc.Cm36 | CYS 20 | - | VdWContact |
| LEU 15 | NTc.Cm34 | CYS 20 | - | Hydrophobic |
| LEU 15 | NTc.Cm34 | ASN 267 | - | VdWContact |
| LEU 15 | NTc.Cm34 | CYS 269 | 7.25x24 | Hydrophobic |
| ARG 16 | NTc.Cm33 | SER 17 | - | VdWContact |
| VAL 17 | NTc.Cm32 | SER 17 | - | VdWContact |
| THR 18 | NTc.Cm31 | TYR 14 | - | Hydrophobic |
| THR 18 | NTc.Cm31 | THR 16 | - | VdWContact |
| THR 18 | NTc.Cm31 | SER 17 | - | HBAcceptor |
| THR 18 | NTc.Cm31 | SER 17 | - | HBDonor |
| THR 18 | NTc.Cm31 | SER 17 | - | VdWContact |
| ARG 20 | NTc.Cm29 | TYR 14 | - | Hydrophobic |
| ARG 20 | NTc.Cm29 | TYR 14 | - | VdWContact |
| ALA 34 | NTc.Cm15 | TYR 184 | - | Hydrophobic |
| GLY 35 | NTc.Cm14 | TYR 187 | 5.31x32 | VdWContact |
| PRO 36 | NTc.Cm13 | SER 179 | 45.51x51 | VdWContact |
| PRO 36 | NTc.Cm13 | SER 180 | 45.52x52 | VdWContact |
| PRO 36 | NTc.Cm13 | HIS 181 | - | Hydrophobic |
| PRO 36 | NTc.Cm13 | HIS 181 | - | VdWContact |
| PRO 36 | NTc.Cm13 | TYR 187 | 5.31x32 | HBAcceptor |
| PRO 36 | NTc.Cm13 | TYR 187 | 5.31x32 | VdWContact |
| GLN 37 | NTc.Cm12 | GLU 172 | - | HBDonor |
| GLN 37 | NTc.Cm12 | GLU 172 | - | VdWContact |
| SER 39 | NTc.Cm10 | TYR 184 | - | VdWContact |
| SER 39 | NTc.Cm10 | TYR 187 | 5.31x32 | VdWContact |
| LYS 40 | NTc.Cm9 | TYR 184 | - | VdWContact |
| VAL 44 | NTc.Cm5 | PRO 19 | - | Hydrophobic |
| GLN 52 | cxb1.1 | GLU 18 | - | VdWContact |
| GLN 52 | cxb1.1 | PRO 19 | - | Hydrophobic |
| GLN 52 | cxb1.1 | PRO 19 | - | VdWContact |
| VAL 53 | cxb1.2 | THR 16 | - | Hydrophobic |
| VAL 53 | cxb1.2 | THR 16 | - | VdWContact |
| CYS 54 | cxb1.5 | SER 17 | - | HBDonor |
| CYS 54 | cxb1.5 | SER 17 | - | VdWContact |
