Predicted complex interactions
CXCL7_HUMAN + CCR5
SUMMARY
- Chemokine
- CXCL7_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 83
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LEU 19 | NTc.Cm44 | LEU 174 | - | Hydrophobic |
| SER 21 | NTc.Cm42 | ILE 23 | 1.25x25 | VdWContact |
| ASP 22 | NTc.Cm41 | HIS 175 | - | HBAcceptor |
| ASP 22 | NTc.Cm41 | HIS 175 | - | Hydrophobic |
| ASP 22 | NTc.Cm41 | HIS 175 | - | VdWContact |
| LEU 23 | NTc.Cm40 | HIS 175 | - | Hydrophobic |
| LEU 23 | NTc.Cm40 | HIS 175 | - | VdWContact |
| TYR 24 | NTc.Cm39 | LYS 26 | 1.28x28 | HBAcceptor |
| TYR 24 | NTc.Cm39 | LYS 26 | 1.28x28 | Hydrophobic |
| TYR 24 | NTc.Cm39 | LYS 26 | 1.28x28 | VdWContact |
| TYR 24 | NTc.Cm39 | GLN 27 | 1.29x29 | Hydrophobic |
| TYR 24 | NTc.Cm39 | GLN 27 | 1.29x29 | VdWContact |
| TYR 24 | NTc.Cm39 | ALA 30 | 1.32x32 | Hydrophobic |
| TYR 24 | NTc.Cm39 | ALA 30 | 1.32x32 | VdWContact |
| ALA 25 | NTc.Cm38 | LYS 26 | 1.28x28 | VdWContact |
| ALA 25 | NTc.Cm38 | THR 177 | - | Hydrophobic |
| ALA 25 | NTc.Cm38 | THR 177 | - | VdWContact |
| GLU 26 | NTc.Cm37 | LYS 26 | 1.28x28 | Anionic |
| GLU 26 | NTc.Cm37 | LYS 26 | 1.28x28 | HBAcceptor |
| GLU 26 | NTc.Cm37 | LYS 26 | 1.28x28 | VdWContact |
| LEU 27 | NTc.Cm36 | LYS 26 | 1.28x28 | VdWContact |
| LEU 27 | NTc.Cm36 | TYR 89 | 2.63x63 | Hydrophobic |
| ARG 28 | NTc.Cm35 | LYS 22 | 1.24x24 | Hydrophobic |
| ARG 28 | NTc.Cm35 | LYS 22 | 1.24x24 | VdWContact |
| ARG 28 | NTc.Cm35 | LEU 275 | 7.31x30 | HBDonor |
| ARG 28 | NTc.Cm35 | LEU 275 | 7.31x30 | VdWContact |
| ARG 28 | NTc.Cm35 | ASP 276 | 7.32x31 | Cationic |
| ARG 28 | NTc.Cm35 | ASP 276 | 7.32x31 | HBDonor |
| ARG 28 | NTc.Cm35 | ASP 276 | 7.32x31 | VdWContact |
| ARG 28 | NTc.Cm35 | MET 279 | 7.35x34 | VdWContact |
| CYS 29 | NTc.Cm34 | LYS 22 | 1.24x24 | HBAcceptor |
| CYS 29 | NTc.Cm34 | LYS 22 | 1.24x24 | VdWContact |
| MET 30 | NTc.Cm33 | PRO 19 | - | Hydrophobic |
| MET 30 | NTc.Cm33 | PRO 19 | - | VdWContact |
| MET 30 | NTc.Cm33 | CYS 20 | - | HBAcceptor |
| MET 30 | NTc.Cm33 | CYS 20 | - | VdWContact |
| MET 30 | NTc.Cm33 | GLN 21 | - | Hydrophobic |
| MET 30 | NTc.Cm33 | GLN 21 | - | VdWContact |
| ILE 32 | NTc.Cm31 | CYS 20 | - | Hydrophobic |
| ILE 32 | NTc.Cm31 | ASN 267 | - | Hydrophobic |
| ILE 32 | NTc.Cm31 | ASN 267 | - | VdWContact |
| ILE 32 | NTc.Cm31 | CYS 269 | 7.25x24 | Hydrophobic |
| ILE 32 | NTc.Cm31 | CYS 269 | 7.25x24 | VdWContact |
| LYS 33 | NTc.Cm30 | THR 16 | - | VdWContact |
| LYS 33 | NTc.Cm30 | SER 17 | - | VdWContact |
| THR 35 | NTc.Cm28 | TYR 14 | - | Hydrophobic |
| THR 35 | NTc.Cm28 | TYR 14 | - | VdWContact |
| GLY 37 | NTc.Cm26 | ILE 12 | - | VdWContact |
| GLY 37 | NTc.Cm26 | TYR 14 | - | HBAcceptor |
| GLY 37 | NTc.Cm26 | TYR 14 | - | VdWContact |
| ILE 38 | NTc.Cm25 | TYR 14 | - | Hydrophobic |
| ILE 38 | NTc.Cm25 | TYR 14 | - | VdWContact |
| LYS 51 | NTc.Cm12 | GLN 170 | - | HBAcceptor |
| LYS 51 | NTc.Cm12 | GLN 170 | - | VdWContact |
| LYS 51 | NTc.Cm12 | HIS 181 | - | HBAcceptor |
| LYS 51 | NTc.Cm12 | HIS 181 | - | VdWContact |
| LYS 51 | NTc.Cm12 | PHE 182 | - | VdWContact |
| LYS 51 | NTc.Cm12 | PRO 183 | - | VdWContact |
| LYS 51 | NTc.Cm12 | TYR 184 | - | HBDonor |
| LYS 51 | NTc.Cm12 | TYR 184 | - | VdWContact |
| GLY 52 | NTc.Cm11 | HIS 181 | - | VdWContact |
| THR 53 | NTc.Cm10 | SER 179 | 45.51x51 | HBDonor |
| THR 53 | NTc.Cm10 | SER 179 | 45.51x51 | VdWContact |
| THR 53 | NTc.Cm10 | SER 180 | 45.52x52 | VdWContact |
| THR 53 | NTc.Cm10 | HIS 181 | - | Hydrophobic |
| THR 53 | NTc.Cm10 | HIS 181 | - | VdWContact |
| ASN 56 | NTc.Cm7 | TYR 187 | 5.31x32 | Hydrophobic |
| ASN 56 | NTc.Cm7 | TYR 187 | 5.31x32 | VdWContact |
| ILE 61 | NTc.Cm2 | PRO 19 | - | Hydrophobic |
| LEU 64 | CX.4 | TYR 14 | - | Hydrophobic |
| ARG 68 | cxb1.5 | ASP 11 | - | Cationic |
| LYS 69 | cxb1.6 | GLU 18 | - | VdWContact |
| LYS 69 | cxb1.6 | PRO 19 | - | Hydrophobic |
| LYS 69 | cxb1.6 | PRO 19 | - | VdWContact |
| ILE 70 | cxb1.8 | TYR 14 | - | Hydrophobic |
| ILE 70 | cxb1.8 | TYR 14 | - | VdWContact |
| ILE 70 | cxb1.8 | SER 17 | - | VdWContact |
| ILE 70 | cxb1.8 | PRO 19 | - | VdWContact |
| CYS 71 | cxb1.10 | SER 17 | - | HBDonor |
| CYS 71 | cxb1.10 | SER 17 | - | VdWContact |
| CYS 71 | cxb1.10 | PRO 19 | - | VdWContact |
| ASP 75 | cxb1.16 | TYR 184 | - | HBAcceptor |
| ASP 75 | cxb1.16 | TYR 184 | - | VdWContact |
