Predicted complex interactions
CXCL9_HUMAN + CCR5
SUMMARY
- Chemokine
- CXCL9_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 110
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 1 | NTc.Cm30 | TRP 86 | 2.60x60 | Hydrophobic |
| THR 1 | NTc.Cm30 | THR 105 | 3.29x29 | Hydrophobic |
| THR 1 | NTc.Cm30 | GLU 283 | 7.39x38 | Cationic |
| PRO 2 | NTc.Cm29 | TRP 86 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm29 | TYR 108 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm29 | GLU 283 | 7.39x38 | Hydrophobic |
| PRO 2 | NTc.Cm29 | GLU 283 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm29 | MET 287 | 7.43x42 | Hydrophobic |
| VAL 3 | NTc.Cm28 | TRP 86 | 2.60x60 | Hydrophobic |
| VAL 3 | NTc.Cm28 | TRP 86 | 2.60x60 | VdWContact |
| VAL 3 | NTc.Cm28 | TYR 89 | 2.63x63 | Hydrophobic |
| VAL 3 | NTc.Cm28 | TYR 89 | 2.63x63 | VdWContact |
| VAL 3 | NTc.Cm28 | ALA 90 | 2.64x64 | Hydrophobic |
| VAL 4 | NTc.Cm27 | TYR 89 | 2.63x63 | Hydrophobic |
| VAL 4 | NTc.Cm27 | TYR 89 | 2.63x63 | VdWContact |
| VAL 4 | NTc.Cm27 | CYS 178 | 45.50x50 | VdWContact |
| ARG 5 | NTc.Cm26 | VAL 25 | 1.27x27 | VdWContact |
| ARG 5 | NTc.Cm26 | ASP 276 | 7.32x31 | HBDonor |
| ARG 5 | NTc.Cm26 | ASP 276 | 7.32x31 | VdWContact |
| ARG 5 | NTc.Cm26 | GLN 277 | 7.33x32 | VdWContact |
| ARG 5 | NTc.Cm26 | GLN 280 | 7.36x35 | HBDonor |
| ARG 5 | NTc.Cm26 | GLN 280 | 7.36x35 | VdWContact |
| LYS 6 | NTc.Cm25 | TYR 187 | 5.31x32 | HBDonor |
| LYS 6 | NTc.Cm25 | TYR 187 | 5.31x32 | VdWContact |
| ARG 8 | NTc.Cm23 | LYS 22 | 1.24x24 | Hydrophobic |
| ARG 8 | NTc.Cm23 | LYS 22 | 1.24x24 | VdWContact |
| ARG 8 | NTc.Cm23 | SER 272 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm23 | ASN 273 | 7.29x28 | HBDonor |
| ARG 8 | NTc.Cm23 | ASN 273 | 7.29x28 | VdWContact |
| ARG 8 | NTc.Cm23 | ASP 276 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm23 | ASP 276 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm23 | ASP 276 | 7.32x31 | VdWContact |
| CYS 9 | NTc.Cm22 | LYS 22 | 1.24x24 | HBAcceptor |
| CYS 9 | NTc.Cm22 | LYS 22 | 1.24x24 | VdWContact |
| SER 10 | NTc.Cm21 | PRO 19 | - | VdWContact |
| SER 10 | NTc.Cm21 | CYS 20 | - | HBAcceptor |
| SER 10 | NTc.Cm21 | CYS 20 | - | HBDonor |
| SER 10 | NTc.Cm21 | CYS 20 | - | VdWContact |
| SER 10 | NTc.Cm21 | LYS 22 | 1.24x24 | VdWContact |
| ILE 12 | NTc.Cm19 | CYS 20 | - | Hydrophobic |
| ILE 12 | NTc.Cm19 | CYS 20 | - | VdWContact |
| ILE 12 | NTc.Cm19 | LYS 22 | 1.24x24 | VdWContact |
| ILE 12 | NTc.Cm19 | ASN 267 | - | VdWContact |
| ILE 12 | NTc.Cm19 | CYS 269 | 7.25x24 | Hydrophobic |
| ILE 12 | NTc.Cm19 | CYS 269 | 7.25x24 | VdWContact |
| SER 13 | NTc.Cm18 | SER 17 | - | HBAcceptor |
| SER 13 | NTc.Cm18 | SER 17 | - | VdWContact |
| THR 14 | NTc.Cm17 | TYR 15 | - | VdWContact |
| ASN 15 | NTc.Cm16 | TYR 15 | - | VdWContact |
| ASN 15 | NTc.Cm16 | THR 16 | - | VdWContact |
| ASN 15 | NTc.Cm16 | SER 17 | - | VdWContact |
| GLN 16 | NTc.Cm15 | TYR 15 | - | Hydrophobic |
| GLN 16 | NTc.Cm15 | TYR 15 | - | VdWContact |
| GLY 17 | NTc.Cm14 | ASN 13 | - | VdWContact |
| GLY 17 | NTc.Cm14 | TYR 14 | - | VdWContact |
| GLY 17 | NTc.Cm14 | TYR 15 | - | VdWContact |
| GLY 17 | NTc.Cm14 | THR 16 | - | VdWContact |
| THR 18 | NTc.Cm13 | ASP 11 | - | Hydrophobic |
| THR 18 | NTc.Cm13 | ASP 11 | - | VdWContact |
| THR 18 | NTc.Cm13 | ILE 12 | - | VdWContact |
| THR 18 | NTc.Cm13 | ASN 13 | - | VdWContact |
| THR 18 | NTc.Cm13 | TYR 14 | - | VdWContact |
| ILE 19 | NTc.Cm12 | ILE 12 | - | HBAcceptor |
| ILE 19 | NTc.Cm12 | ILE 12 | - | HBDonor |
| ILE 19 | NTc.Cm12 | ILE 12 | - | VdWContact |
| ILE 19 | NTc.Cm12 | TYR 14 | - | Hydrophobic |
| ILE 19 | NTc.Cm12 | THR 16 | - | Hydrophobic |
| HIS 20 | NTc.Cm11 | ILE 9 | - | Hydrophobic |
| HIS 20 | NTc.Cm11 | ILE 9 | - | VdWContact |
| HIS 20 | NTc.Cm11 | ASP 11 | - | Hydrophobic |
| HIS 20 | NTc.Cm11 | ASP 11 | - | VdWContact |
| GLN 22 | NTc.Cm9 | ILE 9 | - | Hydrophobic |
| GLN 22 | NTc.Cm9 | ILE 9 | - | VdWContact |
| PRO 32 | CX.4 | TYR 184 | - | Hydrophobic |
| PRO 34 | cxb1.1 | GLU 172 | - | VdWContact |
| PRO 34 | cxb1.1 | SER 179 | 45.51x51 | VdWContact |
| PRO 34 | cxb1.1 | HIS 181 | - | Hydrophobic |
| PRO 34 | cxb1.1 | HIS 181 | - | VdWContact |
| GLU 37 | cxb1.6 | TYR 187 | 5.31x32 | HBAcceptor |
| GLU 37 | cxb1.6 | TYR 187 | 5.31x32 | Hydrophobic |
| GLU 37 | cxb1.6 | TYR 187 | 5.31x32 | VdWContact |
| GLU 37 | cxb1.6 | LYS 191 | 5.35x36 | Anionic |
| GLU 37 | cxb1.6 | LYS 191 | 5.35x36 | HBAcceptor |
| GLU 37 | cxb1.6 | LYS 191 | 5.35x36 | VdWContact |
| ILE 42 | cxb1.14 | PRO 19 | - | Hydrophobic |
| GLN 50 | B1.6 | PRO 19 | - | Hydrophobic |
| GLN 50 | B1.6 | PRO 19 | - | VdWContact |
| THR 51 | B1.7 | THR 16 | - | Hydrophobic |
| THR 51 | B1.7 | THR 16 | - | VdWContact |
| THR 51 | B1.7 | SER 17 | - | HBDonor |
| THR 51 | B1.7 | SER 17 | - | VdWContact |
| THR 51 | B1.7 | PRO 19 | - | VdWContact |
| CYS 52 | b1b2.4 | TYR 15 | - | VdWContact |
| CYS 52 | b1b2.4 | SER 17 | - | HBDonor |
| CYS 52 | b1b2.4 | SER 17 | - | VdWContact |
| CYS 52 | b1b2.4 | PRO 19 | - | VdWContact |
| LEU 53 | b1b2.6 | TYR 14 | - | Hydrophobic |
| LEU 53 | b1b2.6 | TYR 14 | - | VdWContact |
| ASN 54 | b1b2.7 | TYR 14 | - | HBDonor |
| ASN 54 | b1b2.7 | TYR 14 | - | Hydrophobic |
| ASN 54 | b1b2.7 | TYR 14 | - | VdWContact |
| SER 57 | b1b2.10 | TYR 14 | - | VdWContact |
| ASP 59 | b1b2.13 | ILE 12 | - | Hydrophobic |
| ASP 59 | b1b2.13 | ILE 12 | - | VdWContact |
| VAL 60 | b1b2.14 | TYR 14 | - | Hydrophobic |
| VAL 60 | b1b2.14 | TYR 14 | - | VdWContact |
| LEU 63 | B2.2 | ILE 12 | - | Hydrophobic |
| LEU 63 | B2.2 | ILE 12 | - | VdWContact |
| LYS 66 | B2.5 | TYR 10 | - | CationPi |
| LYS 66 | B2.5 | TYR 10 | - | VdWContact |
