Predicted complex interactions
XCL1_HUMAN + CCR5
SUMMARY
- Chemokine
- XCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR5 View partner entry
- Partner description
- UniProt: P51681; Gene: ccr5_human; Family: Chemokine
- Interactions detected
- 74
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm30 | TRP 86 | 2.60x60 | Hydrophobic |
| VAL 1 | NTc.Cm30 | TRP 86 | 2.60x60 | VdWContact |
| VAL 1 | NTc.Cm30 | THR 105 | 3.29x29 | Hydrophobic |
| VAL 1 | NTc.Cm30 | TYR 108 | 3.32x32 | Hydrophobic |
| VAL 1 | NTc.Cm30 | TYR 108 | 3.32x32 | VdWContact |
| VAL 1 | NTc.Cm30 | GLU 283 | 7.39x38 | Cationic |
| VAL 1 | NTc.Cm30 | GLU 283 | 7.39x38 | VdWContact |
| SER 3 | NTc.Cm28 | GLU 283 | 7.39x38 | HBDonor |
| SER 3 | NTc.Cm28 | GLU 283 | 7.39x38 | VdWContact |
| GLU 4 | NTc.Cm27 | LYS 26 | 1.28x28 | Anionic |
| GLU 4 | NTc.Cm27 | TYR 89 | 2.63x63 | Hydrophobic |
| GLU 4 | NTc.Cm27 | TYR 89 | 2.63x63 | VdWContact |
| GLU 4 | NTc.Cm27 | THR 177 | - | HBAcceptor |
| GLU 4 | NTc.Cm27 | THR 177 | - | VdWContact |
| VAL 5 | NTc.Cm26 | VAL 25 | 1.27x27 | Hydrophobic |
| VAL 5 | NTc.Cm26 | VAL 25 | 1.27x27 | VdWContact |
| VAL 5 | NTc.Cm26 | ASP 276 | 7.32x31 | Hydrophobic |
| ASP 7 | NTc.Cm24 | ASN 24 | 1.26x26 | VdWContact |
| LYS 8 | NTc.Cm23 | GLU 172 | - | Cationic |
| LYS 8 | NTc.Cm23 | GLU 172 | - | HBDonor |
| LYS 8 | NTc.Cm23 | GLU 172 | - | VdWContact |
| ARG 9 | NTc.Cm22 | GLU 18 | - | Cationic |
| ARG 9 | NTc.Cm22 | PRO 19 | - | Hydrophobic |
| ARG 9 | NTc.Cm22 | PRO 19 | - | VdWContact |
| ARG 9 | NTc.Cm22 | CYS 20 | - | VdWContact |
| THR 10 | NTc.Cm21 | CYS 20 | - | HBAcceptor |
| THR 10 | NTc.Cm21 | CYS 20 | - | HBDonor |
| THR 10 | NTc.Cm21 | CYS 20 | - | VdWContact |
| THR 10 | NTc.Cm21 | LYS 22 | 1.24x24 | VdWContact |
| VAL 12 | NTc.Cm19 | CYS 20 | - | Hydrophobic |
| VAL 12 | NTc.Cm19 | CYS 20 | - | VdWContact |
| VAL 12 | NTc.Cm19 | ASN 267 | - | VdWContact |
| VAL 12 | NTc.Cm19 | SER 272 | 7.28x27 | VdWContact |
| SER 13 | NTc.Cm18 | THR 16 | - | HBDonor |
| SER 13 | NTc.Cm18 | THR 16 | - | VdWContact |
| THR 15 | NTc.Cm16 | TYR 14 | - | VdWContact |
| THR 15 | NTc.Cm16 | SER 17 | - | VdWContact |
| GLN 17 | NTc.Cm14 | ASN 13 | - | HBAcceptor |
| GLN 17 | NTc.Cm14 | ASN 13 | - | VdWContact |
| GLN 17 | NTc.Cm14 | TYR 14 | - | Hydrophobic |
| ARG 18 | NTc.Cm13 | TYR 14 | - | HBAcceptor |
| ARG 18 | NTc.Cm13 | TYR 14 | - | VdWContact |
| LEU 19 | NTc.Cm12 | TYR 14 | - | Hydrophobic |
| LEU 19 | NTc.Cm12 | TYR 14 | - | VdWContact |
| ARG 23 | NTc.Cm8 | ASP 11 | - | Cationic |
| ILE 29 | NTc.Cm2 | TYR 184 | - | Hydrophobic |
| ILE 29 | NTc.Cm2 | TYR 184 | - | VdWContact |
| GLU 31 | CX.4 | TYR 187 | 5.31x32 | Hydrophobic |
| GLY 32 | CX.5 | TYR 187 | 5.31x32 | VdWContact |
| GLY 32 | CX.5 | LYS 191 | 5.35x36 | HBAcceptor |
| GLY 32 | CX.5 | LYS 191 | 5.35x36 | VdWContact |
| SER 33 | cxb1.1 | LYS 191 | 5.35x36 | HBAcceptor |
| SER 33 | cxb1.1 | LYS 191 | 5.35x36 | VdWContact |
| ARG 35 | cxb1.5 | TYR 184 | - | CationPi |
| ARG 35 | cxb1.5 | TYR 184 | - | VdWContact |
| ARG 35 | cxb1.5 | TYR 187 | 5.31x32 | Hydrophobic |
| ARG 35 | cxb1.5 | TYR 187 | 5.31x32 | VdWContact |
| ILE 38 | cxb1.8 | PRO 19 | - | Hydrophobic |
| ILE 38 | cxb1.8 | PRO 19 | - | VdWContact |
| ARG 43 | cxb1.16 | ASP 11 | - | Cationic |
| ARG 43 | cxb1.16 | ASP 11 | - | HBDonor |
| ARG 43 | cxb1.16 | ASP 11 | - | VdWContact |
| LEU 45 | B1.2 | TYR 14 | - | Hydrophobic |
| LEU 45 | B1.2 | TYR 15 | - | Hydrophobic |
| LYS 46 | B1.3 | GLU 18 | - | Hydrophobic |
| LYS 46 | B1.3 | GLU 18 | - | VdWContact |
| LYS 46 | B1.3 | PRO 19 | - | Hydrophobic |
| VAL 47 | B1.4 | TYR 14 | - | Hydrophobic |
| VAL 47 | B1.4 | SER 17 | - | VdWContact |
| CYS 48 | B1.5 | SER 17 | - | HBDonor |
| CYS 48 | B1.5 | SER 17 | - | VdWContact |
| CYS 48 | B1.5 | PRO 19 | - | VdWContact |
| PRO 51 | b1b2.4 | TYR 184 | - | Hydrophobic |
| PRO 51 | b1b2.4 | TYR 184 | - | VdWContact |
