Predicted complex interactions
CCL19_HUMAN + CCR6
SUMMARY
- Chemokine
- CCL19_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR6 View partner entry
- Partner description
- UniProt: P51684; Gene: ccr6_human; Family: Chemokine
- Interactions detected
- 95
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm28 | GLU 302 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm28 | GLU 302 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm28 | GLU 302 | 7.39x38 | VdWContact |
| THR 2 | NTc.Cm27 | HIS 106 | 2.64x64 | Hydrophobic |
| ASN 3 | NTc.Cm26 | THR 191 | - | HBAcceptor |
| ASN 3 | NTc.Cm26 | THR 191 | - | VdWContact |
| ASN 3 | NTc.Cm26 | VAL 196 | - | Hydrophobic |
| ASN 3 | NTc.Cm26 | VAL 196 | - | VdWContact |
| ASN 3 | NTc.Cm26 | GLU 198 | 45.51x51 | Hydrophobic |
| ASN 3 | NTc.Cm26 | GLU 198 | 45.51x51 | VdWContact |
| ASP 4 | NTc.Cm25 | LYS 298 | 7.35x34 | Anionic |
| ASP 4 | NTc.Cm25 | LYS 298 | 7.35x34 | HBAcceptor |
| ASP 4 | NTc.Cm25 | LYS 298 | 7.35x34 | Hydrophobic |
| ASP 4 | NTc.Cm25 | LYS 298 | 7.35x34 | VdWContact |
| ALA 5 | NTc.Cm24 | LEU 38 | - | Hydrophobic |
| ALA 5 | NTc.Cm24 | LEU 38 | - | VdWContact |
| ALA 5 | NTc.Cm24 | VAL 41 | 1.27x27 | Hydrophobic |
| ALA 5 | NTc.Cm24 | ARG 42 | 1.28x28 | HBAcceptor |
| ALA 5 | NTc.Cm24 | ARG 42 | 1.28x28 | Hydrophobic |
| ALA 5 | NTc.Cm24 | ARG 42 | 1.28x28 | VdWContact |
| GLU 6 | NTc.Cm23 | LEU 38 | - | VdWContact |
| GLU 6 | NTc.Cm23 | THR 191 | - | HBAcceptor |
| GLU 6 | NTc.Cm23 | THR 191 | - | VdWContact |
| GLU 6 | NTc.Cm23 | GLN 192 | - | HBAcceptor |
| GLU 6 | NTc.Cm23 | GLN 192 | - | VdWContact |
| ASP 7 | NTc.Cm22 | LEU 35 | - | Hydrophobic |
| ASP 7 | NTc.Cm22 | CYS 36 | - | VdWContact |
| ASP 7 | NTc.Cm22 | SER 37 | - | VdWContact |
| ASP 7 | NTc.Cm22 | LEU 38 | - | HBAcceptor |
| ASP 7 | NTc.Cm22 | LEU 38 | - | VdWContact |
| ASP 7 | NTc.Cm22 | ARG 42 | 1.28x28 | Anionic |
| ASP 7 | NTc.Cm22 | ARG 42 | 1.28x28 | HBAcceptor |
| ASP 7 | NTc.Cm22 | ARG 42 | 1.28x28 | VdWContact |
| ASP 7 | NTc.Cm22 | GLN 192 | - | HBAcceptor |
| ASP 7 | NTc.Cm22 | GLN 192 | - | HBDonor |
| ASP 7 | NTc.Cm22 | GLN 192 | - | VdWContact |
| CYS 8 | NTc.Cm21 | LEU 35 | - | VdWContact |
| CYS 8 | NTc.Cm21 | CYS 36 | - | HBAcceptor |
| CYS 8 | NTc.Cm21 | CYS 36 | - | HBDonor |
| CYS 8 | NTc.Cm21 | CYS 36 | - | VdWContact |
| LEU 10 | NTc.Cm19 | CYS 36 | - | Hydrophobic |
| LEU 10 | NTc.Cm19 | ASN 285 | - | HBAcceptor |
| LEU 10 | NTc.Cm19 | ASN 285 | - | VdWContact |
| LEU 10 | NTc.Cm19 | ARG 286 | - | Hydrophobic |
| LEU 10 | NTc.Cm19 | ARG 286 | - | VdWContact |
| LEU 10 | NTc.Cm19 | CYS 288 | 7.25x24 | Hydrophobic |
| LEU 10 | NTc.Cm19 | CYS 288 | 7.25x24 | VdWContact |
| LEU 10 | NTc.Cm19 | GLU 291 | 7.28x27 | Hydrophobic |
| LEU 10 | NTc.Cm19 | GLU 291 | 7.28x27 | VdWContact |
| SER 11 | NTc.Cm18 | GLU 32 | - | VdWContact |
| THR 13 | NTc.Cm16 | TYR 27 | - | HBAcceptor |
| THR 13 | NTc.Cm16 | MET 33 | - | VdWContact |
| LYS 15 | NTc.Cm14 | TYR 27 | - | Hydrophobic |
| ILE 17 | NTc.Cm12 | TYR 27 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | TYR 27 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | TYR 27 | - | VdWContact |
| TYR 20 | NTc.Cm9 | PHE 19 | - | Hydrophobic |
| TYR 20 | NTc.Cm9 | PHE 19 | - | VdWContact |
| ILE 21 | NTc.Cm8 | TYR 27 | - | Hydrophobic |
| LEU 28 | NTc.Cm1 | LEU 35 | - | Hydrophobic |
| LEU 28 | NTc.Cm1 | GLN 192 | - | Hydrophobic |
| ILE 30 | CX.5 | PRO 207 | 5.31x32 | Hydrophobic |
| ILE 30 | CX.5 | ILE 208 | 5.32x33 | Hydrophobic |
| LYS 31 | cxb1.1 | GLN 202 | - | Hydrophobic |
| ASP 32 | cxb1.2 | THR 191 | - | Hydrophobic |
| ASP 32 | cxb1.2 | THR 191 | - | VdWContact |
| ARG 35 | cxb1.8 | ALA 279 | 6.60x60 | HBDonor |
| ARG 35 | cxb1.8 | ALA 279 | 6.60x60 | VdWContact |
| ARG 35 | cxb1.8 | ASN 280 | 6.61x61 | VdWContact |
| ARG 35 | cxb1.8 | LEU 281 | 6.62x62 | HBDonor |
| ARG 35 | cxb1.8 | LEU 281 | 6.62x62 | VdWContact |
| ARG 35 | cxb1.8 | GLY 282 | 6.63x63 | VdWContact |
| ARG 35 | cxb1.8 | LYS 283 | 6.64x64 | VdWContact |
| ARG 35 | cxb1.8 | ARG 286 | - | VdWContact |
| VAL 36 | cxb1.9 | MET 284 | 6.65x65 | Hydrophobic |
| VAL 36 | cxb1.9 | MET 284 | 6.65x65 | VdWContact |
| VAL 40 | cxb1.15 | LEU 35 | - | Hydrophobic |
| VAL 40 | cxb1.15 | LEU 35 | - | VdWContact |
| ARG 47 | B1.6 | VAL 29 | - | VdWContact |
| ARG 47 | B1.6 | LEU 34 | - | Hydrophobic |
| GLN 48 | B1.7 | LEU 34 | - | VdWContact |
| GLN 48 | B1.7 | LEU 35 | - | HBAcceptor |
| GLN 48 | B1.7 | LEU 35 | - | Hydrophobic |
| GLN 48 | B1.7 | LEU 35 | - | VdWContact |
| LEU 49 | b1b2.4 | TYR 27 | - | Hydrophobic |
| LEU 49 | b1b2.4 | VAL 29 | - | Hydrophobic |
| LEU 49 | b1b2.4 | MET 33 | - | VdWContact |
| LEU 49 | b1b2.4 | LEU 34 | - | Hydrophobic |
| CYS 50 | b1b2.6 | MET 33 | - | HBDonor |
| CYS 50 | b1b2.6 | MET 33 | - | VdWContact |
| CYS 50 | b1b2.6 | LEU 35 | - | VdWContact |
| ARG 60 | B2.2 | TYR 18 | - | CationPi |
| ARG 64 | B2.6 | PHE 19 | - | VdWContact |
| MET 72 | B3.4 | PHE 8 | - | Hydrophobic |
| MET 72 | B3.4 | PHE 8 | - | VdWContact |
